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Prostatic Neoplasms clinical trials

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NCT ID: NCT03404648 Not yet recruiting - Clinical trials for Prostate Adenocarcinoma

Staging Prostate Cancer With Hybrid C11-Choline PET/MR and mpMRI

Start date: February 2018
Phase: Phase 3
Study type: Interventional

The purpose of this study is to find out if a PET/MR scan in combination with standard MRI and CT scans can improve the early detection and treatment of patients with prostate cancer.

NCT ID: NCT03403595 Recruiting - Clinical trials for Metastatic Castration-resistant Prostate Cancer

177Lu-EB-PSMA617 in Patients With Metastatic Castration-resistant Prostate Cancer

Start date: December 1, 2017
Phase: Phase 1
Study type: Interventional

This is an open-label, non-controlled, non-randomized study to assess the safety and measure image-based absorbed dose of 177Lu-EB-PSMA-617 in patients with metastatic castration-resistant prostate cancer (mCRPC) who will undergo radioliagnd therapy using 177Lu-EB-PSMA-617. All patients underwent whole-body 68Ga-PSMA PET/CT for selection and accepted intravenous injection with single dose 0.80-1.1 GBq (21.5-30 mCi) of 177Lu-EB-PSMA-617 within one week, then monitored at 2, 24, 72, 120 and 168 h after 177Lu-EB-PSMA617 administration with serial whole body planar and SPECT/CT imaging.

NCT ID: NCT03397160 Recruiting - Prostate Cancer Clinical Trials

Pioneering Advances in Care and Education (PACE)

PACE
Start date: October 10, 2017
Phase: N/A
Study type: Interventional

This clinical trial evaluates the use of novel decision support educational materials and services using health coaches. The study includes men newly diagnosed with low-risk prostate cancer. A 160 men will be recruited. Half of the men will receive a call from a health coach before their initial consultation visit with their urologist to review their treatment concerns and questions. The other half will receive usual care provided by the urologist, such as educational materials and services provided by the urologist.

NCT ID: NCT03397030 Recruiting - Prostatic Neoplasm Clinical Trials

Impact of Exercise on Prognostic Biomarkers Related to Prostate Cancer

Start date: January 5, 2017
Phase: N/A
Study type: Interventional

The goal of this study is to demonstrate the impact of a home based exercise program versus wait-list control to modulate circulating prognostic biomarkers in men with prostate cancer under active surveillance.

NCT ID: NCT03396874 Not yet recruiting - Prostate Cancer Clinical Trials

Gallium-68 PSMA-11 PET in Patients With Biochemical Recurrence

Start date: January 2018
Phase: Phase 2
Study type: Interventional

This study evaluates the value of Gallium-68 labeled PSMA (68Ga-PSMA) for PET/CT imaging of prostate cancer recurrence. 68Ga-PSMA is a radioactive molecule, which binds to prostate cancer cells. Together with a PET/CT scanner, the distribution of 68Ga-PSMA can be determined in the body. To test this new drug, participants will receive an intravenous injection of Ga-68-PSMA and then have a PET/CT scan. The scan results will be made available to study participants and treating physicians.

NCT ID: NCT03396848 Recruiting - Prostate Cancer Clinical Trials

Sexual Health and Rehabilitation eClinic (SHAReClinic)

Start date: August 23, 2017
Phase: N/A
Study type: Interventional

In addressing the need for effective post treatment support for men (and their partners) following treatment for prostate cancer, the investigators will employ an innovative SHAReClinic (Sexual health and Rehabilitation eClinic Program) that emphasizes: 1) a bio-medical component (erectile rehabilitation), focused on the long term return of erectile functioning firm enough for penetration with or without erectile agents/devices; and 2) a psychological component (intimacy maintenance), involving the maintenance or restoration of couples' intimacy. Through comparison research, the eClinic will be analyzed and made comparable in quality to the programs offered currently at leading institutions in major metropolitan areas, thus providing personalized, comprehensive cancer care to all Canadians.

NCT ID: NCT03392428 Not yet recruiting - Metastatic Cancer Clinical Trials

A Trial of 177Lu-PSMA617 Theranostic Versus Cabazitaxel in Progressive Metastatic Castration Resistant Prostate Cancer

TheraP
Start date: January 2018
Phase: Phase 2
Study type: Interventional

This open label, randomised, stratified, 2-arm, multicentre, phase 2 trial aims to determine the activity and safety of Lu-PSMA vs cabazitaxel in men with progressive metastatic castration resistant prostate cancer

NCT ID: NCT03392233 Recruiting - Breast Cancer Clinical Trials

Stereotactic Body Radiation Therapy for Spinal Metastases in Favorite Tumors

Start date: August 18, 2017
Phase: Phase 2
Study type: Interventional

Stereotactic Body Radiation Therapy(SBRT) for spinal metastases has been proved a good results in pain relieve and local control, However,the longterm of efficacy and safety of this regimen is unclear.The purpose of the study is to evaluate the longterm outcome of this therapeutic regimen in selective patients who will be survival more than 2 years.

NCT ID: NCT03392181 Not yet recruiting - Prostate Cancer Clinical Trials

PET/MRI for the Staging of Newly Diagnosed Prostate Cancer

Start date: January 20, 2018
Phase: Phase 2
Study type: Interventional

The purpose of this study is to gain understanding of how PET-MR (positron emission tomography-magnetic resonance imaging) using the substance 18F-DCFPyL (PyL) may help in diagnosing prostate cancer and in determining the stage of prostate cancer before surgery.

NCT ID: NCT03390127 Recruiting - Prostatic Neoplasms Clinical Trials

Effect of PEEP on Arterial Oxygen Partial Pressure in Elderly Patients With Lithotomy Position Using LMA Supremeā„¢

Start date: January 5, 2018
Phase: N/A
Study type: Interventional

The purpose of the present study is to compare the effect of PEEP on arterial oxygen partial pressure in elderly patients undergoing urologic surgery using LMA supremeā„¢ in a lithotomy position.