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NCT ID: NCT00208507 Completed - Joint Diseases Clinical Trials

28 mm Ceramic-on-Ceramic Acetabular Cup Total Hip Replacement Study

Start date: April 1, 2003
Phase: N/A
Study type: Interventional

The study is designed to evaluate artificial hips with a 28 mm ceramic head and a ceramic liner to determine whether they perform as well as artificial hips with a 28 mm ceramic head and a polyethylene liner.

NCT ID: NCT00572416 Completed - Breast Cancer Clinical Trials

Fatigue in Breast Cancer: A Behavioral Sleep Intervention

Start date: April 1, 2003
Phase: N/A
Study type: Interventional

1. This randomized clinical trial compares a four component behavioral sleep intervention group to an attention control healthy eating group 2. The behavioral sleep intervention is designed to reduce fatigue in women with stages I-IIIA breast cancer receiving anthracycline-based chemotherapy 3. The intervention uses an Individual Sleep Promotion Plan to promote daytime activity and nighttime sleep,and to decrease physchological and symptom distress 4. The healthy eating group receives equal time and attention and information on healthy eating 5. All participants receive a research nurse visit 2 days prior to each chemotherapy treatment, and 30, 60, 90 days after the last treatment, and one-year after the first treatment. 6. Adherence to the intervention is calculated at each time 7. Reliable and valid instruments are used, including wrist actigraphy

NCT ID: NCT00622336 Completed - Multiple Myeloma Clinical Trials

A Companion Study for Studies THAL-MM-003, CC-5013-MM-009, and CC-5013-MM-010 for Subjects With Multiple Myeloma

Start date: April 1, 2003
Phase: Phase 3
Study type: Interventional

The study evaluated the safety of Lenalidomide monotherapy in participants with advanced multiple myeloma who had discontinued treatment with combination thalidomide plus high-dose dexamethasone or high-dose dexamethasone alone in studies Thal-MM-003, CC-5013-MM-009 and CC-5013-MM-010 due to the development of documented disease progression or the inability to tolerate the lowest dosing regimen per previous protocol of thalidomide and/or high-dose dexamethasone without grade 3 or 4 toxicity.

NCT ID: NCT00651274 Completed - Atherosclerosis Clinical Trials

Comparison of Co-administration of Ezetimibe Plus Simvastatin Versus Simvastatin Alone in Primary Hypercholesterolemia (P03476)

Start date: April 1, 2003
Phase: Phase 4
Study type: Interventional

This study will assess whether the daily co-administration of ezetimibe 10 mg with ongoing treatment of simvastatin 20 mg will be more effective than treatment with simvastatin 20 mg alone in further reducing LDL-C concentrations.

NCT ID: NCT00783354 Completed - Urticaria Clinical Trials

A Comparison of Aerius Continuous Treatment Versus Aerius PRN for Chronic Idiopathic Urticaria (Study P03147)

ATTITUD
Start date: April 1, 2003
Phase: Phase 4
Study type: Interventional

This double-blind pilot study was conducted to establish the best way of using desloratadine treatment to protect quality of life of chronic idiopathic urticaria (CIU) patients, after an initial 4-weeks of daily treatment: prolonging systematic daily treatment or as needed (PRN; in the case of symptoms).

NCT ID: NCT00953719 Completed - Clinical trials for Non-inflammatory Degenerative Joint Disease

36 mm Ceramic-on-Ceramic Acetabular Cup Total Hip Replacement

Start date: April 1, 2003
Phase: N/A
Study type: Interventional

This study is a supplement to the 28 mm Ceramic-on-Ceramic study which was designed to evaluate artificial hips with a 28 mm ceramic head and liner to determine whether they perform as well as artificial hips with a 28 mm ceramic head and a polyethylene liner. This arm of the study is designed to compare a 36 mm ceramic head and sleeve with a subset of the control (28mm ceramic head and a polyethylene sleeve) from the original study (G030075) (NCT#00208507) with additional follow-up, to determine if they perform as well.

NCT ID: NCT03151616 Completed - Aged Clinical Trials

Anticholinergic Risk Scale and Resource Use After Elective Noncardiac Surgery

Start date: April 1, 2003
Phase: N/A
Study type: Observational

This study investigates the association of preoperative anticholinergic medication exposure with healthcare resource utilization in a population-based sample of older patients enrolled in a universal pharmacare program

NCT ID: NCT00106301 Completed - Prostatic Neoplasms Clinical Trials

Continuation Trial Evaluating the Tolerability and Activity of FK228 in Patients That Completed Prior Study With FK228

Start date: April 1, 2004
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the safety and tolerability of extended treatment with FK228 in patients with metastatic renal cell carcinoma or hormone refractory prostate cancer who have at least demonstrated stable disease on prior Fujisawa sponsored FK228 clinical trials.

NCT ID: NCT00157157 Completed - Hemophilia A Clinical Trials

Efficacy and Safety Study of a Recombinant Protein-Free Manufactured Factor VIII (rAHF-PFM) in Previously Untreated Hemophilia A Patients

Start date: April 1, 2004
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate whether Antihemophilic factor, recombinant, manufactured protein-free (rAHF-PFM) is effective and safe in the treatment of hemophilia A patients who have not been treated with factor VIII (FVIII) before.

NCT ID: NCT00159029 Completed - Alpha Thalassemia Clinical Trials

Genetics of Alpha Thalassemia in Israeli Ethnic Groups

Start date: April 1, 2004
Phase: N/A
Study type: Observational

Alpha thalassemia causes mild anemia and is found in many ethnic groups. Usually it is found in regions where malaria is endemic. We have found that alpha thalassemia is common in Ashkenazim, whose countries of origin are in temperate climates. We are analyzing the alpha globin genes of individuals of many ethnic groups and will compare to try to define the origin of thalassemia in these individuals of European extraction.