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NCT ID: NCT02217826 Completed - Healthy Clinical Trials

Single Dose Pharmacodynamic and Pharmacokinetic Study of DG3173

Start date: n/a
Phase: Phase 1
Study type: Interventional

In this single-dose, randomized, 5-way cross-over study, healthy volunteers were treated with the highest approved dose of octreotide, three different doses of Somatoprim (DG3173) and placebo control. The main purpose of the study was to investigate the effects of each treatment on the control of plasma glucose as well as the secretion of insulin and glucagon following a standard meal.

NCT ID: NCT02223416 Completed - Healthy Clinical Trials

A Study Aimed at Assessing the Pharmacokinetic Properties of RGB-10 and Forsteo

Start date: n/a
Phase: Phase 1
Study type: Interventional

Pharmacokinetic properties, safety and tolerability of RGB-10 and Forsteo will be compared in healthy female volunteers.

NCT ID: NCT02230657 Completed - Clinical trials for Osteoarthritis of the Hip

A Prospective, Randomized Trial Comparing Same Day Discharge and Overnight Hospital Stay Among Total Hip Arthroplasties Done by the Direct Anterior Approach

Start date: n/a
Phase: N/A
Study type: Interventional

The purpose of this study is to identify differences in satisfaction, pain and length of stay between patients undergoing hip replacement who are discharged from the hospital on the day of surgery compared to patients who stay one night in the hospital.

NCT ID: NCT02327754 Completed - Clinical trials for Diabetic Nephropathy

Effect of Topiroxostat on Urinary Albumin Excretion Early Stage Diabetic Nephropathy and Hyperuricemia With or Without Gout

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Start date: n/a
Phase: Phase 2
Study type: Interventional

The purpose of this study is to investigate the effect of topiroxostat on urinary albumin excretion and the safety in patients with early stage diabetic nephropathy and hyperuricemia with or without gout. Participants are randomized to placebo (n=20) or topiroxostat (n=40) for 28 weeks. The investigational drugs for this study are supplied by FUJI YAKUHIN CO., LTD.

NCT ID: NCT02385396 Completed - Infertility Clinical Trials

Myo-inositol Therapy on the Dynamics of Embryo Development in Patients Suffering From PCOS Undergoing ICSI Treatment

Start date: n/a
Phase: Phase 2
Study type: Interventional

The purpose of this study is to analyse the activity of myo-inositol on pregnancy rate, embryo development dynamics and oestradiol and progesterone concentration in blood serum and Superoxide Dismutase (SOD) and catalase concentration in follicular fluid of patients with Polycystic Ovary Syndrome (PCOS) undergoing Intracytoplasmic Sperm Injection (ICSI).

NCT ID: NCT02389569 Completed - Dental Caries Clinical Trials

Clinical Study of Biosilicate Under Resin Composite Restorations in Caries Affected Teeth

Start date: n/a
Phase: N/A
Study type: Interventional

This study aimed to evaluate the clinical performance of a novel vitro-ceramic biomaterial (Biosilicate®) as treatment of caries-affected dentin in posterior resin restorations. A total of 94 restorations of 66 participants were selected and assigned at random into four groups: 1 (Biosilicate / Two-step etch and rinse system), 2 (Control / Two-step etch and rinse system), 3 (Biosilicate / Two-step self-etching system) and 4 (Control / Two-step self-etching system). Two operators carried out the adhesive protocols and restored the cavities with a nano-hybrid resin composite (IPS Empress, Ivoclar) using the incremental technique. Participants were recalled at one week, 6, 12 and 18 months for clinical evaluation performed by two blinders and calibrated examiners according FDI criteria.

NCT ID: NCT02434835 Completed - Clinical trials for Healthy Male Subject

Study of Absorption, Metabolism and Excretion Following a Single Oral Dose of [14C]KWA-0711 to Healthy Male Subjects

Start date: n/a
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the absorption, metabolism and excretion following a single oral dose of [14C]KWA-0711 to healthy male subjects.

NCT ID: NCT02503163 Completed - Clinical trials for Dry Eye With Sjögren's Syndrome

A Long-term Study of KCT-0809 in Dry Eye Patients With Sjögren's Syndrome

Start date: n/a
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate of the long-term safety and efficacy of KCT-0809 in dry eye patients with Sjögren's syndrome.

NCT ID: NCT02503189 Completed - Clinical trials for Dry Eye With Sjögren's Syndrome

A Phase III Study of KCT-0809 in Dry Eye Patients With Sjögren's Syndrome

Start date: n/a
Phase: Phase 3
Study type: Interventional

The purpose of this study is to investigate the superiority of KCT-0809 to placebo, and to evaluate safety in dry eye patients with Sjögren's syndrome

NCT ID: NCT02511418 Completed - Hypertension Clinical Trials

Renal Hemodynamic Effects of the HMG-CoA Reductase Inhibitors in Normal Volunteers and in Patients With Chronic Renal Failure

Start date: n/a
Phase: N/A
Study type: Interventional

This study was done to determine whether Simvastatin (a medication commonly used to treat patients with high cholesterol levels in the blood increases blood flow to the kidneys and improves renal function in normal volunteers and patients with impaired renal function secondary to polycystic kidney diseases.