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NCT ID: NCT00344695 Completed - Nicotine Dependence Clinical Trials

Bupropion Treatment for Youth Smoking Cessation

Start date: n/a
Phase: Phase 3
Study type: Interventional

The purpose of this study is to 1) evaluate the safety and efficacy of two doses of bupropion SR (150mg/day and 300mg/day) when compared to placebo, as an aid to smoking cessation in adolescents and 2) to examine which factors, such as medication adherence, nicotine dependence, and motivation to quit, affect treatment outcome.

NCT ID: NCT00344734 Completed - Clinical trials for Congestive Heart Failure

Effects of Acute L-NMMA Treatment on Renal Hemodynamics and Vasoactive Hormones in Patients With Congestive Heart Failure

Start date: n/a
Phase: Phase 1
Study type: Interventional

The study tests the hypothesis that nitric oxide availability is changed in congestive heart failure with regard to the regulation of renal hemodynamics, renal sodium excretion and release of vasoactive hormones. The study tests these hypotheses by comparing the effects of systemic nitric oxide inhibition with L-NMMA in congestive heart failure patients with healthy subjects on renal hemodynamics, blood pressure and plasma levels of vasoactive hormones.

NCT ID: NCT00344916 Completed - Liver Cirrhosis Clinical Trials

Phase 1 Study of L-NMMA in Patients With Liver Cirrhosis

Start date: n/a
Phase: Phase 1
Study type: Interventional

Phase 1 study of the effects of nitric oxide inhibition with L-NMMA in patients with liver cirrhosis and healthy controls. It is hypothesized that nitric oxide availability is increased in liver cirrhosis.

NCT ID: NCT00345137 Completed - Glomerulonephritis Clinical Trials

Effects of Systemic NO-Inhibition on Renal Hemodynamics in Patiens With Polycystic Kidney Disease and Chronic Glomerulonephritis

Start date: n/a
Phase: Phase 1
Study type: Interventional

The study tests the hypothesis that systemic and renal nitric oxide availability is changed in polycystic kidney disease and chronic glomerulonephritis.

NCT ID: NCT00345150 Completed - Hypertension Clinical Trials

Effects of Inhibition of NO-Synthesis on Renal Hemodynamics and Sodium Excretion in Patients With Essential Hypertension and Healthy Controls

Start date: n/a
Phase: Phase 1
Study type: Interventional

The study tests the hypothesis that systemic and renal nitric oxide synthesis is changed in essential hypertension by investigating the effects of a non selective nitric oxide inhibitor on renal hemodynamics and sodium excretion in patients with essential hypertension. The results are compared with a group of healthy subjects.

NCT ID: NCT00347503 Completed - Cataract Clinical Trials

Aqueous Concentrations and PGE2 Inhibition of Ketorolac 0.4% vs. Bromfenac 0.09% in Cataract Patients

Start date: n/a
Phase: Phase 4
Study type: Interventional

Evaluation of the aqueous concentrations of 2 topical NSAIDS as well as the PGE2 inhibition in human patients.

NCT ID: NCT00347802 Completed - Glaucoma Clinical Trials

Diurnal Curves With Bimatoprost 0.03% Versus Travoprost 0.004%

Start date: n/a
Phase: Phase 4
Study type: Interventional

To compare the diurnal curves in patients using bimatoprost 0.03% versus travoprost 0.004% for the treatment of glaucoma or ocular hypertension.

NCT ID: NCT00347841 Completed - Glaucoma Clinical Trials

Efficacy of Bimatoprost 0.03% in Patients Who Are Low-Responders to Latanoprost

Start date: n/a
Phase: Phase 4
Study type: Interventional

To evaluate the IOP-lowering efficacy of bimatoprost 0.03% in patients found to be low-responders to latanoprost therapy.

NCT ID: NCT00348023 Completed - Glaucoma Clinical Trials

Bimatoprost Monotherapy vs. Dual Therapy With Travoprost and Timolol in Patients With Glaucoma and Ocular Hypertension

Start date: n/a
Phase: Phase 4
Study type: Interventional

Evaluate the IOP-lowering efficacy and quality of life in patients using bimatoprost 0.03% monotherapy versus dual therapy with travoprost 0.004% and timolol 0.5% for the treatment of glaucoma or ocular hypertension.

NCT ID: NCT00348062 Completed - Glaucoma Clinical Trials

A Multicenter Evaluation of Methods to Reduce Hyperemia Associated With Bimatoprost Therapy for Glaucoma or Ocular Hypertension

Start date: n/a
Phase: Phase 4
Study type: Interventional

Evaluate the incidence of hyperemia in patients using bimatoprost and to determine if simple interventions reduce its incidence and to assess the value of detailed instruction in increasing patient compliance and willingness to continue bimatoprost therapy, despite the occurrence of hyperemia.