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NCT number NCT03455270
Study type Interventional
Source G1 Therapeutics, Inc.
Contact G1 Therapeutics Clinical Contact
Phone 919-213-9835
Status Not yet recruiting
Phase Phase 1
Start date May 2018
Completion date May 2022

Clinical Trial Summary

This is a study to investigate the potential clinical benefit of G1T48 as an oral selective estrogen receptor degrader (SERD) in patients with estrogen receptor-positive, HER2-negative metastatic breast cancer.

The study is an open-label design, consisting of 2 parts: dose-finding portion (Part 1), and expansion portion (Part 2). Both parts include 3 study phases: Screening Phase, Treatment Phase, and Survival Follow-up Phase. The Treatment Phase begins on the day of first dose with study treatment and completes at the Post-Treatment Visit. Approximately, 96 patients will be enrolled in the study.

Clinical Trial Description


Study Design

Related Conditions & MeSH terms

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