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Body Weight clinical trials

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NCT ID: NCT00498394 Completed - Obesity Clinical Trials

Effects of a Ketogenic Diet on Body Weight and Cardiovascular Risk Factors

Start date: June 2000
Phase: Phase 1
Study type: Interventional

This pilot study is a randomized, controlled clinical trial to compare anthropometric and metabolic changes associated with six months of weight management by means of a very low carbohydrate diet or a calorically-restricted low fat diet. We hypothesized that the low fat diet would be associated with more weight loss and improvement of cardiovascular risk factors than the low carbohydrate diet.

NCT ID: NCT00489593 Completed - Weight Loss Clinical Trials

Olanzapine in Patients With Advanced Cancer and Weight Loss

Start date: October 2006
Phase: Phase 1
Study type: Interventional

The goal of this clinical research study is to find the highest tolerable dose of the drug Olanzapine that can be given to patients with advanced cancer who are experiencing weight loss. Researchers want to find out if Olanzapine can help decrease weight loss in patients who are experiencing it because of cancer. How this drug affects performance status, cancer-related symptoms, and nutritional status in patients with advanced cancer will also be studied.

NCT ID: NCT00456911 Completed - Primary Prevention Clinical Trials

Family Dietary Coaching to Improve Nutritional Intakes and Body Weight Control

ELPAS
Start date: March 2005
Phase: N/A
Study type: Interventional

We hypothesize that Family Dietary Coaching for one school year will allow a nutritional shift towards following recommendations and improve health indicators in free-living children and adults.

NCT ID: NCT00451399 Completed - Weight Gain Clinical Trials

Efficacy of Lifestyle Interventions and Metformin for the Treatment of Antipsychotic-Induced Weight Gain

Start date: October 2004
Phase: Phase 4
Study type: Interventional

Lifestyle intervention and certain medications have been shown to be effective for antipsychotic-induced weight gain, but no controlled studies have compared psychological and pharmacological therapies. We conducted a randomized, placebo-controlled study to test the efficacy of lifestyle intervention and metformin alone and in combination for antipsychotic-induced weight gain.

NCT ID: NCT00422058 Completed - Obesity Clinical Trials

The Effect of Liraglutide on Body Weight in Obese Subjects Without Diabetes

Start date: January 10, 2007
Phase: Phase 2
Study type: Interventional

This trial is conducted in Europe. The purpose of the 20-week trial is to investigate the efficacy of liraglutide to induce body weight loss and the purpose of the extension is to evaluate the long term safety and tolerability of liraglutide. Trial has the following trial periods: A 20-week randomised, double-blind, placebo-controlled, six-armed parallel-group, multi-centre, multinational trial with an open label orlistat comparator arm followed by an 84 week extension period.

NCT ID: NCT00409305 Completed - Obesity Clinical Trials

The Effect of Betahistine on Body Weight in Obese Subjects

Start date: January 2007
Phase: Phase 2
Study type: Interventional

The purpose of this study is to examine the effect that betahistine has on body weight in obese subjects.

NCT ID: NCT00402077 Completed - Obesity Clinical Trials

A Study to Examine the Safety, Tolerability, and Body Weight Effect of Pramlintide Alone and in Combination With Oral Antiobesity Agents in Overweight and Obese Subjects

Start date: November 2006
Phase: Phase 2
Study type: Interventional

This study will examine the safety, tolerability, and body weight effect of subcutaneous pramlintide alone and in various combinations with the oral antiobesity agents sibutramine or phentermine in overweight and obese subjects.

NCT ID: NCT00394095 Completed - Bipolar Disorder Clinical Trials

Topiramate vs. Placebo in Preventing Weight Gain in Bipolar Disorder Treated With Olanzapine

Start date: December 2006
Phase: Phase 4
Study type: Interventional

The primary objective of this study is to examine the efficacy of topiramate in combination with olanzapine for the prevention of weight gain in youth with bipolar disorder. The secondary objective is to examine the tolerability of topiramate in combination with olanzapine for the prevention of weight gain in youth with bipolar disorder.

NCT ID: NCT00392925 Completed - Obesity Clinical Trials

A Study to Evaluate the Effect on Body Weight of Leptin Administered in Conjunction With Pramlintide in Overweight and Obese Subjects

Start date: October 2006
Phase: Phase 2
Study type: Interventional

This study will evaluate the safety, tolerability, and effect on body weight of leptin, injected subcutaneously, in combination with pramlintide, injected subcutaneously.

NCT ID: NCT00363376 Completed - Weight Gain Clinical Trials

A Study of Zonisamide to Prevent Olanzapine-Associated Weight Gain

Start date: January 2008
Phase: Phase 3
Study type: Interventional

The specific aim of this study is to evaluate the efficacy, tolerability, and safety of zonisamide therapy in the prevention of weight gain associated with olanzapine treatment for psychotic or bipolar disorders.