Clinical Trials Logo

Walking, Difficulty clinical trials

View clinical trials related to Walking, Difficulty.

Filter by:

NCT ID: NCT06247553 Recruiting - Stroke Clinical Trials

To Develop a Walking Exercise Program for Non-ambulatory Stroke Survivors

Start date: February 2, 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to test a gait (walking) training program in non-ambulatory (unable to walk) chronic stroke survivors. The main question it aims to answer is: • Will gait training improve the cardiovascular system in non-ambulatory chronic stroke survivors better than a sitting leg cycling exercise? Participants will walk on a treadmill with a partial body-weight support system and the gait training device. Researchers will compare with a leg-cycling exercise to see if there are significant differences in resting heart rate, systolic blood pressure (SBP), and A1c levels in the blood.

NCT ID: NCT06165016 Recruiting - Aging Clinical Trials

Far Red Light to Improve Functioning in PAD

LIGHT PAD
Start date: February 14, 2024
Phase: N/A
Study type: Interventional

The LIGHT PAD Trial is a Phase II multi-centered randomized clinical trial to collect preliminary data to test whether daily far red light treatment of the lower extremities in people with PAD improves six-minute walk distance, lower extremity perfusion, and ischemia-related damage in gastrocnemius muscle at four-month follow-up, compared to a sham control. Participants will complete 10 minutes of twice daily home treatment with either far red light or a sham light for four months.

NCT ID: NCT06137456 Completed - Clinical trials for Spinal Cord Injuries

First Report of a New Exoskeleton in Incomplete Spinal Cord Injury

Start date: January 1, 2022
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to compare the effects of exoskeletal robotic therapy and conventional exercise therapy in incomplete spinal cord injury (SCI). The main questions it aims to answer are: - Is exoskeletal robotic therapy effective in improving functional ambulation in SCI? - Is exoskeletal robotic therapy effective in enhancing Activities of Daily Living in SCI? Participants treated with either: - Exoskeletal robotic therapy along with conventional exercise therapy, or - Only conventional exercise therapy.

NCT ID: NCT06137443 Completed - Clinical trials for Spinal Cord Injuries

Enhancing Balance and Mobility in Incomplete Spinal Cord Injury

Start date: January 1, 2022
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to compare the effects of balance therapy with an overground gait trainer in incomplete spinal cord injury (SCI). The main questions it aims to answer are: - Is balance therapy with an overground gait trainer effective in improving functional ambulation in SCI? - Is balance therapy with an overground gait trainer effective in enhancing Activities of Daily Living in SCI? Participants treated with either: • Overground gait trainer along with conventional exercise therapy

NCT ID: NCT06113965 Recruiting - Stroke Clinical Trials

Neural Operant Conditioning

Start date: May 31, 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to learn if operant conditioning can reduce spasticity in order to improve walking in stroke patient. The main questions it aims to answer are: - Can participants self-regulate reflex excitability - Can participants self-regulate reflex, reduce spasticity and improve walking Participants will undergo surface stimulation to evoke spinal reflexes and will be asked to control these reflexes therefore reducing spasticity. Researchers will compare result to able bodied participants to see if [insert effects]

NCT ID: NCT06107556 Not yet recruiting - Stroke Clinical Trials

Agonist and Antagonist Muscle Activations in the Lower Limbs During Walking After Central Nervous System Injury

NEUROGAIT
Start date: October 19, 2023
Phase:
Study type: Observational

The retrospective study investigates the part of responsibility of neuromuscular disorders associated with chronic hemiparesis in walking impairment.

NCT ID: NCT06073028 Completed - Parkinson Disease Clinical Trials

Model-based Cueing-as-needed for Walking in Parkinson's Disease

GAITPARK
Start date: February 1, 2021
Phase: N/A
Study type: Interventional

Correcting of the lack of regularity in steps is a key component of gait rehabilitation in Parkinson's disease. The proposal is to introduce adaptive spatial auditory cueing (ASAC) based on verbal instruction "lengthen the step" automatically delivered when the stride length decreased below a predetermined threshold. The present study compared the effect of usual rhythmic auditory cueing versus ASAC used during a walking training in Parkinson's disease.

NCT ID: NCT06059872 Recruiting - Stroke Clinical Trials

Biomarkers of Reaction To HIIT Exercise

BReaTHE
Start date: January 1, 2024
Phase: N/A
Study type: Interventional

Stroke survivors with lower limb disability can improve their walking speed with high-intensity interval training (HIIT) rehabilitation therapy. However, some individuals may not respond to HIIT even when fully adherent to the program. To address this, the investigators propose to build a predictive model that identifies if a Veteran with chronic subcortical stroke will improve their walking speed with HIIT by incorporating blood lactate as an early predictor of exercise response, and inhibitory neurotransmitter gamma-aminobutyric acid (GABA) and regional cerebral blood flow (CBF) as predictors of the brain's potential to respond, while also taking into consideration other factors such as comorbidities, demographics, and fitness levels.

NCT ID: NCT06032065 Recruiting - Aging Clinical Trials

Sequential Multiple Assessment Randomized Trial of Exercise for PAD: SMART Exercise for PAD (SMART PAD)

Start date: September 8, 2023
Phase: Phase 3
Study type: Interventional

Supervised exercise therapy (SET), consisting of treadmill exercise conducted three times weekly at a center while supervised by healthcare personnel, is first line therapy for people disabled by lower extremity peripheral artery disease (PAD). However, travelling three times/week to a center for SET is burdensome. Compared to SET, home-based exercise is more accessible and less burdensome. Yet, evidence-based guidelines recommend SET over home-based exercise for PAD. Walking exercise is first line therapy to improve walking distance for PAD, but it does not eliminate ischemic leg symptoms in most people with PAD. The investigators' work and that of others showed that nitrate-rich beetroot juice, which increases plasma nitrite, limb perfusion, and skeletal muscle function, significantly improved exercise tolerance and reduced non-response to exercise in people with and without PAD. The investigators will use a 2 x 2 factorial design to address two major barriers to achieving benefits from exercise therapy for PAD: First, guideline recommendations for supervised exercise therapy (SET) as first line therapy for PAD. Second, the inability of exercise therapy to eliminate PAD-related disability in most people with PAD. Participants will be randomized to one of four groups for 12 weeks: Supervised treadmill exercise + nitrate rich beetroot juice; supervised treadmill exercise + placebo, home-based walking exercise + nitrate rich beetroot juice, home-based walking exercise + placebo.

NCT ID: NCT06003868 Completed - Cerebral Palsy Clinical Trials

Investigation of the Effect of Hippotherapy Simulator in Children With Spastic Diplegia and Cerebral Palsy

Start date: September 1, 2023
Phase: N/A
Study type: Interventional

The aim of the study is to examine the effect of hippotherapy simulator on trunk control, balance and gait in children with spastic diplegia cerebral palsy and its relationship with quality of life.