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Vomiting clinical trials

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NCT ID: NCT00930332 Terminated - Pain Clinical Trials

Methadone Hydrochloride as First-Line Therapy in Treating Patients With Chronic Neuropathic Cancer Pain

Start date: June 17, 2010
Phase: Phase 1
Study type: Interventional

RATIONALE: Methadone hydrochloride may reduce chronic neuropathic pain in patients with cancer. PURPOSE: This phase I trial is studying the side effects and best dose of methadone hydrochloride as first-line therapy in treating patients with chronic neuropathic cancer pain.

NCT ID: NCT00903396 Terminated - Colorectal Cancer Clinical Trials

Palonosetron Hydrochloride in Preventing Nausea and Vomiting Caused by Radiation Therapy in Patients With Primary Abdominal Cancer

Start date: September 2009
Phase: Phase 2
Study type: Interventional

RATIONALE: Palonosetron hydrochloride may prevent nausea and vomiting caused by radiation therapy. It is not yet known whether palonosetron hydrochloride is more effective than a placebo in preventing nausea and vomiting. PURPOSE: This randomized phase II trial is studying the side effects of palonosetron hydrochloride and to see how well it works in preventing nausea and vomiting caused by radiation therapy in patients with primary abdominal cancer.

NCT ID: NCT00900068 Terminated - Breast Cancer Clinical Trials

Blood Samples From Patients on a Clinical Trial to CINV During HSCT

Start date: August 2008
Phase: N/A
Study type: Observational

RATIONALE: Studying samples of blood in the laboratory from patients with cancer may help doctors learn more about nausea and vomiting caused by cancer treatment. PURPOSE: This laboratory study is looking at blood samples from patients with cancer who were treated on a clinical trial to control nausea and vomiting during donor stem cell transplant.

NCT ID: NCT00895245 Terminated - Nausea and Vomiting Clinical Trials

Fosaprepitant Dimeglumine, Palonosetron Hydrochloride, and Dexamethasone in Preventing Nausea and Vomiting Caused by Cisplatin in Patients With Stage III or Stage IV Head and Neck Cancer Undergoing Chemotherapy and Radiation Therapy

Start date: February 2009
Phase: Phase 2
Study type: Interventional

RATIONALE: Fosaprepitant dimeglumine, palonosetron hydrochloride, and dexamethasone may help lessen or prevent nausea and vomiting caused by cisplatin in patients with head and neck cancer undergoing chemotherapy and radiation therapy. PURPOSE: This phase II trial is studying how well fosaprepitant dimeglumine together with palonosetron hydrochloride and dexamethasone works in preventing nausea and vomiting caused by cisplatin in patients with stage III or stage IV head and neck cancer undergoing chemotherapy and radiation therapy.

NCT ID: NCT00888329 Terminated - Clinical trials for Postoperative Nausea and Vomiting

Aprepitant for Prevention of Postoperative Nausea and Vomiting in Elective Hysterectomy

Start date: July 2007
Phase: Phase 4
Study type: Interventional

The purpose of the study is to determine whether 40 mg aprepitant administered before surgery is effective for preventing vomiting in the first 24 hours after surgery in women undergoing elective hysterectomy.

NCT ID: NCT00869973 Terminated - Emesis Clinical Trials

Aprepitant in the Prevention of Delayed Emesis Induced by Cyclophosphamide Plus Anthracyclines in Breast Cancer Patients

Start date: September 2009
Phase: Phase 3
Study type: Interventional

The aim of the study is to compare efficacy and tolerability of aprepitant versus dexamethasone in the prevention of delayed emesis induced by moderately emetogenic chemotherapy (cyclophosphamide plus anthracyclines) in breast cancer patients.

NCT ID: NCT00869310 Terminated - Emesis Clinical Trials

Aprepitant in the Prevention of Cisplatin-induced Delayed Emesis

Start date: September 2009
Phase: Phase 3
Study type: Interventional

The aim of the study is to compare efficacy and tolerability of aprepitant plus dexamethasone versus metoclopramide plus dexamethasone in the prevention of cisplatin-induced delayed emesis in patients that received aprepitant, palonosetron and dexamethasone before chemotherapy administration for the prevention of acute emesis.

NCT ID: NCT00861523 Terminated - Clinical trials for Hyperemesis Gravidarum

Does Thiamine Help Vomiting and Nausea in Pregnancy?

Start date: February 2009
Phase: Phase 3
Study type: Interventional

There are different treatments for nausea and vomiting in pregnancy. According to the ACOG recommendations, promethazine is the first line of parenteral treatment after oral treatment had failed. Thiamine is given to prevent wernicke encephalopathy. This research try to find out whether thiamine helps the vomiting and nausea as well, by comparing the response to thiamine and promethazine in women who suffer from nausea and vomiting in pregnancy.

NCT ID: NCT00818259 Terminated - Clinical trials for Chemotherapy-Induced Nausea and Vomiting

A Study of MK-0869 (Aprepitant) and MK-0517 (Fosaprepitant) in Pediatric Participants Receiving Chemotherapy (MK-0869-134)

Start date: February 5, 2009
Phase: Phase 1
Study type: Interventional

This study will determine the appropriate dosing regimen of aprepitant and fosaprepitant for the prevention of chemotherapy-induced nausea and vomiting in pediatric participants from 0 months to 17 years of age.

NCT ID: NCT00761254 Terminated - Nausea Clinical Trials

Domperidone for Relief of Gastrointestinal Disorders

Start date: August 2008
Phase: N/A
Study type: Interventional

The purpose of this study is to make Domperidone available to patients with gastrointestinal disorders who have failed standard therapy and who might benefit from it.