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Urolithiasis clinical trials

View clinical trials related to Urolithiasis.

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NCT ID: NCT01792765 Completed - Urolithiasis Clinical Trials

Management of Ureteral Calculi Using Ultrasound Guidance: A Radiation Free Approach

Start date: October 2011
Phase: N/A
Study type: Interventional

Kidney stones are very common, and can inflict a significant degree of pain and renal damage. Some stones become obstructed in the ureter, the tube that drains the kidney. In order to remove these stones, an Urologist and their team use fluoroscopic guidance to do so, this involves continuous X-ray. Flouroscopy delivers a significant dose of radiation to the patient, as well as the health care team, which has been shown to have serious health consequences. Previous studies have shown that in certain populations, like pregnant women, stones can be managed using ultrasound guidance. The investigators propose that mid and distal ureteral stones could be managed using ultrasound guidance in conjunction with conventional stone removal techniques (ureteroscopy, lithotripsy, and ureteral stent placement), in lieu of fluoroscopy, thereby minimizing radiation to healthcare staff and patients. The investigators hypothesize that distal ureteral stones can be identified and efficiently fragmented and removed under ultrasound guidance in a safe and effective manner without the use of radiation.

NCT ID: NCT01736358 Terminated - Urolithiasis Clinical Trials

The Use of Intranasal Ketoralac for Pain Management (Sprix)

Start date: October 2012
Phase: Phase 4
Study type: Interventional

Despite an overall reduction in the perioperative complication rate, post operative pain management after ureteroscopic removal of stones (URS) remains a major factor delaying discharge of patients. The investigators hypothesize that perioperative usage of intranasal ketorolac will provide a reduction in post operative opioid requirements, better post operative pain control, higher anesthesia satisfaction and faster recovery.

NCT ID: NCT01637506 Recruiting - Urolithiasis Clinical Trials

Urine and Stool Analysis in Kidney Stone Disease

Start date: July 2012
Phase:
Study type: Observational

The purpose of this study is to add to the investigators' quest to understanding stone disease, by evaluating the metabolites excretion in urine and its relation to microflora present in the stool.

NCT ID: NCT01589484 Completed - Urolithiasis Clinical Trials

Impact of Renal Anatomy on Shock Wave Lithotripsy Outcomes for Lower Pole Kidney Stones

Start date: April 2012
Phase: N/A
Study type: Interventional

Kidney stone disease affects almost 10% of overall population, often requiring a surgical intervention. Currently, shock wave lithotripsy is considered a first-line treatment option for patients suffering from symptomatic kidney stones smaller than 2.0 cm, providing reasonable stone-free rate. Actually, the outcomes from SWL vary largely due to several factors including stone burden, stone density, stone-skin distance (SSD), and patient's body habitus. Furthermore, the imaging exam modality (i.e. ultrasound versus computed tomography scan) performed to assess the presence of residual fragments also impacts on SWL outcome analysis. We aim to perform a well-controlled prospective evaluation of all variables that may impact on fragmentation and clearance of lower pole calculi after SWL. These variables are assessed exclusively by a noncontrast computed tomography scan (NCCT), eliminating the necessity of an intravenous urography to study renal collecting system anatomy; an imaging exam that is not routinely performed anymore for kidney stone patients.

NCT ID: NCT01451931 Completed - Urolithiasis Clinical Trials

Study of Tomography of Nephrolithiasis Evaluation

STONE
Start date: September 2011
Phase: Phase 4
Study type: Interventional

This is a multi-center, randomized controlled trial of ultrasonography (ultrasound) compared to computed tomography (CT) for the initial emergency room evaluation of patients with suspected renal colic. The investigators will compare several measures of effectiveness including morbidity related to the patient's underlying disease, or complications related to delayed diagnosis, patient status regarding pain/missed days of work, and utilization of health care resources based on one of three study arms: ultrasound in the Emergency Department, ultrasound in Radiology or CT.

NCT ID: NCT01431378 Terminated - Lung Cancer Clinical Trials

Pilot Study of Model Based Iterative Reconstruction Using 64-Slice

MBIR
Start date: September 2011
Phase: N/A
Study type: Observational

This study is being performed to confirm that the new technique, Model-Based Iterative Reconstruction (MBIR) with reduced radiation dose can deliver equivalent image quality for CT scans compared to current techniques (Filtered Back Projection with Adaptive Statistical Iterative Reconstruction (FBP with ASiR) and also to demonstrate that MBIR can improve general image quality characteristics at equivalent radiation dose levels.

NCT ID: NCT01361516 Not yet recruiting - Urolithiasis Clinical Trials

Comparison of General Anaesthesia and Sedation on the Stone Fragmentation in Lithotripsy

Start date: July 2011
Phase: N/A
Study type: Interventional

The aim of the study is to compare the impact intravenous sedation versus general anesthesia on the efficacy of stone fragmentation in extracorporeal shock wave lithotripsy treatment.

NCT ID: NCT01349764 Terminated - Urolithiasis Clinical Trials

Effect of Vitamin D Replacement in Patients With Urolithiasis

Start date: April 2011
Phase: N/A
Study type: Observational

When Vitamin D replacement is initiated in patients with history of urolithiasis, there will be higher incidence of hypercalciuria but with careful follow-up of these patients, hypercalciuria could be appropriately managed with thiazide diuretics so that the risk of newly diagnosed renal stones will be equivalent to control groups without Vitamin D replacements.the purpose of the study is to determine the effect of vitamin D replacement in patients with previous history of urolithiasis presenting to a tertiary stone clinic in terms of changes in 24-hour urine collection parameters and to evaluate the lithogenic effect of vitamin D replacement in terms of development of urolithiasis. Eighty-six eligible patients will be included in terms of having suboptimal vitamin D with history of calcareous urolithiasis and urinary calcium excretion <7.5 mmol/day. Patients will be randomly divided into 2 equal groups depending on whether they will receive vitamin D replacement with follow-up at 3, 6, 12, & 24 months.

NCT ID: NCT01330940 Completed - Urolithiasis Clinical Trials

Effect of Diet Orange Soda on Urinary Lithogenicity

Start date: November 2009
Phase: N/A
Study type: Interventional

Beverages containing citrate may be useful in increasing urine citrate content and urine pH. Such changes in urine chemistry could help prevent kidney stones. Diet orange soda has more citrate than other similar beverages. The investigators are interested in whether diet soda will improve urine chemistry in the appropriate manner.

NCT ID: NCT01318187 Completed - Urolithiasis Clinical Trials

Intravenous Paracetamol or Morphine for the Treatment of Acute Flank Pain

Start date: January 2011
Phase: Phase 4
Study type: Interventional

STUDY OBJECTIVE: This randomized, controlled trial evaluates the analgesic efficacy and safety of intravenous single-dose paracetamol and morphine for the treatment of acute flank pain. METHODS: The investigators conducted a randomized, double-blind, controlled clinical trial comparing single intravenous doses of paracetamol (1 g) and morphine (0.1 mg/kg) for patients presenting to the emergency department (ED) with acute flank pain. Subjects with inadequate pain relief at 30 minutes received rescue fentanyl (0.75 microg/kg).