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Urolithiasis clinical trials

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NCT ID: NCT02214836 Not yet recruiting - Urolithiasis Clinical Trials

Ultrasound Imaging of Kidney Stones and Lithotripsy

Start date: October 1, 2024
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether new software processing of ultrasound images can improve detection and size determination of kidney stones.

NCT ID: NCT02211313 Terminated - Urinary Stones Clinical Trials

Evaluation of Ureteral Stents in the Management of Stone Disease

Start date: August 2014
Phase: N/A
Study type: Interventional

A thin tube, called a ureteral stent, is inserted into the ureter and is commonly used as treatment of urinary stone disease. Stents are designed to help provide drainage of the kidney in the setting of an obstructing stone, or postoperative swelling of the ureter. Though their presence is only temporary, stents are associated with a significant amount of patient discomfort and bother, which can negatively impact overall satisfaction. Over the past decades, there have been refinements in stent technology and usage philosophy. Smaller and softer stents are now available for use in patients, though studies evaluating the relative benefits have been conflicting. The investigators aim to evaluate the effect of stent size and composition upon outcomes after the treatment of stone disease, including patient comfort and satisfaction.

NCT ID: NCT02188108 Completed - Urolithiasis Clinical Trials

Validation of the Wisconsin Stone-QOL

Start date: July 2014
Phase: N/A
Study type: Interventional

The overall purpose of this study is to evaluate criterion-related validity of a newly-developed disease-specific instrument to assess the health-related quality of life (HRQOL) of patients who have had kidney stones. Specific aims of this study are: 1. Aim 1. Evaluate the population/external validity (generalizability) of the Wisconsin Stone-QOL by answering the question, "Is the Wisconsin Stone-QOL useful for assessing the HRQOL of patients who form kidney stones from a broad region of North America?" 2. Aim 2. Assess the ability of the Wisconsin Stone-QOL to detect changes within patients related to stone interventions and other disease-specific outcomes by answering the question, "Is the Wisconsin Stone-QOL sensitive to changes in stone-related outcomes within individuals?"

NCT ID: NCT02140970 Completed - Urolithiasis Clinical Trials

Randomized Trial of NSAID vs Placebo Prior to Ureteral Stent Removal

Start date: May 2014
Phase: N/A
Study type: Interventional

This study plans to learn more about whether ibuprofen can reduce pain after removal of a ureteral stent more than a placebo. Some patients experience pain after removal of a ureteral stent. The investigators plan to learn how often this occurs and whether it can be prevented. The investigators hypothesize that children who have a temporary, indwelling ureteral stent will experience a significantly less post-operative pain if given a non-steroidal anti-inflammatory (NSAID) prior to removal of the ureteral stent when compared to placebo. The investigators hypothesize that the incidence of severe post-stent removal pain is similar to an adult population.

NCT ID: NCT02123082 Recruiting - Urolithiasis Clinical Trials

Multi-Center Comparison of Dual Lumen Versus Single Lumen Ureteroscopes

Start date: July 2, 2014
Phase: N/A
Study type: Interventional

Urolithiasis (kidney stones) is a common disease process affecting people all across the world. Usually, if the stone size is small, it is able to pass through the urinary system and exit the bladder on its own with no treatment. However, when the size of the stone is bigger, it can get trapped in the kidney or the ureter, causing significant pain for the patient and potentially obstructing urine flow. If this occurs, surgical treatment is necessary for the removal of the stone. The surgical procedure often employed involves the use of a ureteroscope, which is a device that includes a camera and channels for working instruments such as a grasper and laser fiber to be placed during a procedure. Ureteroscopes that are currently in use are flexible and have the ability to treat stones that may otherwise be inaccessible in the kidney. Most flexible ureteroscopes in clinical use currently only have one channel therefore only allowing one instrument to be used at a time. Recently, a new type of ureteroscope has been introduced in the market that offers the advantage of having two working channels where two instruments can be inserted for use during stone treating procedure. This can potentially decrease procedure time for patients affected by kidney stones. The purpose of this research is to compare the efficacy and safety of the ureteroscopes that have only one channel for instrument insertion with the newer ureteroscope that has two channels for utilization during stone treatment.

NCT ID: NCT02092558 Completed - Clinical trials for System and Hematuria.

Evaluation of Immunological Disorders of T Lymphocytes and Endocrinological Disorders as Pathogen Factors in Patients With Metaplasia of Urinary Bladder

Start date: January 2005
Phase: N/A
Study type: Observational

Background: Squamous metaplasia refers to the pathological transformation of the urothelium leading to non-keratinised stratified squamous metaplasia (N-KSM). Objective: To present the investigators experiences in the diagnosis and treatment of N-KSM of the urinary bladder in children.

NCT ID: NCT02028559 Active, not recruiting - Urolithiasis Clinical Trials

Safety and Effectiveness of the Ultrasonic Propulsion of Kidney Stones

Start date: January 2014
Phase: N/A
Study type: Interventional

This study tests moving kidney stones using focused ultrasound (referred to as ultrasonic propulsion). The study includes multiple population groups to investigate the ability of our technology to: a) move stone fragments to a location within the kidney to improve their chances of passage, and thus reduce the occurrence of additional symptomatic events and retreatment or b) move a symptomatic stone to relieve symptoms and pain.

NCT ID: NCT01873690 Terminated - Urolithiasis Clinical Trials

Efficacy of Antimicrobial Prophylaxis for Shock Wave Lithotripsy (SWL) on Reducing Urinary Tract Infection (UTI)

Start date: November 2013
Phase: Phase 3
Study type: Interventional

The purpose of this research study is to test whether administering one dose of an antibiotic before a routine shock wave lithotripsy procedure is more effective at avoiding any urinary infections compared to not taking an antibiotic. This is an important topic to study because urinary tract infections are one of the most common complications after this procedure and there is no clear standard of care regarding the use of pre-procedure antibiotics. Our study results will benefit future patients either by decreasing the rate of infections or decreasing the use of unnecessary antibiotics.

NCT ID: NCT01847963 Completed - Urolithiasis Clinical Trials

A Clinical Study to Evaluate the Efficacy of Two Siddha Drugs Sindhuvallathy Mezhugu and Kalladaippu Kudineer for Kidney Stones

SVMKK
Start date: June 2012
Phase: N/A
Study type: Interventional

This study is a non randomized non comparative study with two Siddha formulations Sindhuvallathy Mezhugu and Kalladaippu Kudineer are available in Siddha classical texts existing for longer period. But there is no scientific data is documented about these formulations. This study aimed to evaluate the efficacy of the study drugs for urolithiasis. After the preliminary drug standardization the clinical study is Started at The National Institute of Siddha Tambaram. The primary outcome measure is either the Expulsion of stones or Changes in the number and size of the stones with 45 days drug treatment.

NCT ID: NCT01807260 Completed - Clinical trials for Pediatric Urinary Lithiasis

Stepwise Shock Wave Lithotripsy in Pediatric Urolithiasis

Start date: March 2008
Phase: N/A
Study type: Interventional

To evaluate and compare the results of conventional and stepwise shock wave lithotripsy treatment modalities in pediatric urinary lithiasis.