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Resveratrol for the Treatment of Non Alcoholic Fatty Liver Disease and Insulin Resistance in Overweight Adolescents

TYPE 2 DIABETES Clinical Trial

Official title:
Safety and Efficacy of Resveratrol for the Treatment of Non-Alcoholic Fatty Liver Disease and Associated Insulin Resistance in Overweight and Obese Adolescents

Clinical Trial Summary

The current project is designed as a 30-day pilot trial to demonstrate the safety and tolerability of resveratrol therapy in overweight adolescents to decrease liver fat, and improve insulin sensitivity to prevent type 2 diabetes.

Clinical Trial Description

Pilot study of 10 overweight or obese children with MRS determined fatty liver randomized to resveratrol or placebo. Primary outcome measures include change in liver triglyceride content as determined by MRS and improvement in insulin resistance as determined by the area under the curve of glucose excursion during a 75 gram oral glucose tolerance test. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02216552
Study type Interventional
Source University of Manitoba
Contact
Status Completed
Phase Phase 2/Phase 3
Start date August 2015
Completion date March 20, 2017
View Details
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