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Tumor clinical trials

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NCT ID: NCT04075305 Recruiting - Breast Cancer Clinical Trials

The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study

MOMENTUM
Start date: February 1, 2019
Phase:
Study type: Observational [Patient Registry]

The Multi-OutcoMe EvaluatioN of radiation Therapy Using the Unity MR-Linac Study (MOMENTUM) is a multi-institutional, international registry facilitating evidenced based implementation of the Unity MR-Linac technology and further technical development of the MR-Linac system with the ultimate purpose to improve patients' survival, local, and regional tumor control and quality of life.

NCT ID: NCT03912168 Completed - Pain Clinical Trials

Question Prompt List for Orthopaedic Conditions

Start date: August 12, 2019
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate whether providing patients with a question prompt list (QPL) prior to their orthopaedic surgery clinic appointment improves their perceived involvement in care (PICs) score compared to being given 3 questions from the AskShareKnow model

NCT ID: NCT03905733 Recruiting - Tumor Clinical Trials

The Effects of High-flow Nasal Oxygen on Oxygenation During Rigid Bronchoscopy Under General Anesthesia in Pediatric Patients

Start date: April 2019
Phase:
Study type: Observational

The aim of this study is to evaluate the effect of high-flow nasal cannula oxygen administration on maintenance of oxygenation and removal of carbon dioxide during apnoeic period in pediatric patients undergoing general anesthesia with rigid bronchoscopy

NCT ID: NCT03900078 Completed - Soft Tissue Sarcoma Clinical Trials

Incisional Negative Pressure Wound Therapy for Resection of Soft Tissue Tumors

Start date: December 1, 2018
Phase: N/A
Study type: Interventional

This study is aimed to examine the value of incisional negative pressure therapy after resection of soft tissue tumors. Its a prospective randomized trial comparing incisional negative pressure to standard wound dressings.

NCT ID: NCT03892408 Completed - Tumor Clinical Trials

High-flow Nasal Oxygen During Rigid Bronchoscopy Under General Anesthesia: a Randomized Controlled Trial

Start date: April 21, 2019
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the effect of high-flow nasal cannula oxygen administration on apnea in patients undergoing general anesthesia with rigid bronchoscopy compared with standard anesthesia methods.

NCT ID: NCT03775694 Completed - Healthy Clinical Trials

Diffusion MRI-1 Imaging Database

dMRI-1
Start date: June 6, 2019
Phase:
Study type: Observational

The purpose of the dMRI-1 data collection study is to establish a database of clinical images and limited medical history information from patients that have previously received a dMRI scan. All data collected will be de-identified. No safety or effectiveness assessments will be completed.

NCT ID: NCT03619356 Enrolling by invitation - Diabetes Clinical Trials

Investigation of Hemoglobin Oxygenation With Third Harmonic Generation Microscopy

Start date: February 5, 2018
Phase:
Study type: Observational

The specific aims of the project are performing a pre-clinical study on a human model and evaluating the oxygenation and other status of human erythrocytes by spectrally-resolved third harmonic generation (srTHG) microscopy . By analyzing the partitioned third harmonic generation (THG) spectra of oxygenated and deoxygenated erythrocytes ex vivo, the investigators aim to provide a reference standard for quantifying oxygenation and molecular status in this project.

NCT ID: NCT03513757 Completed - Headache Clinical Trials

Dexmedetomidine and Propofol for Pediatric MRI Sedation

Start date: March 4, 2018
Phase: Phase 4
Study type: Interventional

The purpose of this study is to compare the results of combining two anesthetic medications (dexmedetomidine and propofol) in low doses with a standard dose of a single drug that is commonly used to provide sedation/anesthesia for MRI studies in young children (propofol). The drugs used for the MRI scan in this study will be chosen randomly. Half the patients will receive small doses of propofol and dexmedetomidine. The other half will receive propofol administered constantly throughout the scan. Other drugs that may be used include sevoflurane and nitrous oxide at the start of the sedation (for placing an intravenous), lidocaine (to reduce the pain of propofol injection) and glycopyrrolate (to prevent the heart rate from decreasing too low. The investigators will record 5 additional blood pressures and heart rates. If additional medications are required to complete the scan, the investigators will administer whatever is necessary. At the end of the study, the investigators will have an observer record the time it takes for participants to spontaneously open eyes , to be able to drink liquids and/or eat and to behave as before the study. Also, it is very important that the investigators find out from participants about changes in behavior, or if eating or sleeping habits were unusual following completion of the study. For that reason, the investigators will call participants in a day or so following the MRI scan. The investigators expect to recruit 40 children between the ages of 12 and 72 months for the study and hope to have the study completed in December 2018.

NCT ID: NCT03489187 Completed - Epilepsy Clinical Trials

Visualase Visualization Database (VIVID-1)

VIVID-1
Start date: March 5, 2018
Phase:
Study type: Observational

The purpose of the VIVID-1 data collection study is to establish a database of clinical images and associated technical files from commercial cases using the Visualase Thermal Therapy System (VTTS). All data collected will be de-identified. No safety or effectiveness assessments will be completed.

NCT ID: NCT03474289 Recruiting - Tumor Clinical Trials

Safety and Tolerability of SHR-1316 in Subjects With Advanced Tumors

Start date: March 1, 2018
Phase: Phase 1
Study type: Interventional

The purpose of this study is to access the safety and tolerability of the study drug known as SHR-1316 in metastatic/advanced malignancies