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Traumatic Brain Injury clinical trials

View clinical trials related to Traumatic Brain Injury.

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NCT ID: NCT06193382 Not yet recruiting - Clinical trials for Traumatic Brain Injury

Parent-Child Interaction Therapy (PCIT) for Children With Traumatic Brain Injury (TBI): A Stepped-Care Model

Start date: August 1, 2024
Phase: N/A
Study type: Interventional

The purpose of this study is to understand how a stepped-care model of Parent-Child Interaction Therapy (Step-Up PCIT) addresses child behavioral problems among children between the ages of 2 and 7 with a traumatic brain injury (TBI).

NCT ID: NCT06192342 Recruiting - Stroke Clinical Trials

Ventilatory Parameters in Acute Neurological Injury

Start date: May 1, 2024
Phase:
Study type: Observational [Patient Registry]

The goal of this observational study is to test the association between baseline ventilatory parameters (in particular mechanical power (MP), mechanical power normalized to predicted body weight (MP/PBW) and driving pressure (DP) with the baseline neurological status (assessed through the Glasgow coma score) in adults patients under mechanical ventilation with acute neurological injury secondary to stroke, brain trauma or subarachnoid hemorrhage. The main question[s]it aims to answer are: 1. In patients with acute neurological injury under mechanical ventilation, is there a correlation between the acute neurological injury, assessed using the Glasgow scale on admission, and baseline ventilatory parameters? 2. In patients with acute neurological injury under mechanical ventilation, are the baseline ventilatory parameters altered at baseline?

NCT ID: NCT06188364 Recruiting - Clinical trials for Traumatic Brain Injury

Improving Traumatic Brain Injury Rehab Care With Comm Health Services: a Research Project Within the TBI Model System

Start date: April 26, 2024
Phase: Early Phase 1
Study type: Interventional

TBI rehabilitation care transitions refer to the processes of preparing patients, families, and community-based healthcare providers for the patient's passage from inpatient rehabilitation to the home and community or to another level of care. Persons with TBI have heterogenous neurological impairment (cognitive and behavioral foremost, along with motor, sensory, and balance), that limits their functional independence and participation, and increases their risk for secondary medical conditions, injuries, rehospitalizations and early mortality

NCT ID: NCT06184932 Recruiting - Clinical trials for Traumatic Brain Injury

TeleRehab to Restore Upper Limb Function in People With Chronic TBI

Start date: April 1, 2023
Phase: N/A
Study type: Interventional

The study aims to inform the subsequent large-scale clinical trial focused on using telerehabilitation techniques and technologies to improve upper limb function and quality of life.

NCT ID: NCT06184828 Not yet recruiting - Clinical trials for Traumatic Brain Injury

Pilot Study of Whole Blood Transfusion for Trauma Brain Injury (TBI)

Start date: August 1, 2024
Phase: Phase 3
Study type: Interventional

Our goal is to perform a pilot, single center study to evaluate the efficacy of whole blood (WB) in subjects with TBI, intracranial hemorrhage, and anemia compared to blood component therapy.

NCT ID: NCT06184295 Recruiting - Clinical trials for Traumatic Brain Injury

Robotic Balance Training to Improve Postural Control and Balance Post-Traumatic Brain Injury

Start date: January 1, 2024
Phase: N/A
Study type: Interventional

The purpose of this study is to assess a balance training program to see if it can be helpful to improve balance and avoid falls in people who have had traumatic brain injuries (TBIs). The study will involve three groups of research subjects: 1) TBI-intervention group, 2) TBI- non-intervention group and 3) the participants without disability group. The TBI intervention Group will participate in 10 robotic balance training sessions. Data will collected pre and post-training. TBI- non-intervention group will not receive any training. They will participate in two data collection sessions which are about 5 weeks apart. The participants without disability group will not receive any training. They will participate in one data collection session.

NCT ID: NCT06177509 Recruiting - Clinical trials for Traumatic Brain Injury

Effect of Graded Aerobic Exercise in Mild Traumatic Brain Injury

Start date: November 17, 2023
Phase: N/A
Study type: Interventional

There is a paucity of knowledge about mechanisms behind mild traumatic brain injury (mTBI) subgroup's sustained problems, and effective interventions that can alleviate this disabling condition. Persistent Post-concussive Symptoms (PCS) affect between 20% and 30% of individuals after mTBI. This Randomized Controlled Trial (RCT) will investigate whether graded aerobic exercise has a positive effect on symptom burden (including exercise intolerance) and Autonomic Nervous System (ANS) dysfunction in patients with PCS. This study will expand upon previous work on adolescents with sport-related concussion in the acute phase. It will cover a wider age group and will include patients with persisting symptoms, thus providing knowledge on whether a sub-symptom threshold aerobic exercise program will alleviate symptom burden in adult patients with PCS. Furthermore - looking into the relationship between mTBI and ANS function, this study is expected to contribute to a better understanding of the neurobiological factors involved in PCS. The results may also help developing targeted interventions to specific characteristics in persistent symptoms after mTBI.

NCT ID: NCT06156735 Completed - Stroke Clinical Trials

Music Therapy on Cognition in Neurorehabilitation

Start date: May 1, 2018
Phase: N/A
Study type: Interventional

Music therapy has received more attention with its surging application in neuro-rehabilitation overseas. Given the dearth of music therapy and cognitive rehabilitation research conducted in Malaysia, this pilot study intended to investigate the effect of active and passive music therapy interventions versus the standard care condition in cognition among adults with neuro-rehabilitation needs.

NCT ID: NCT06149975 Recruiting - Clinical trials for Traumatic Brain Injury

Feasibility of a Motor-cognitive Training Program in Patients With Traumatic Brain Injury

Start date: November 20, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical study is to test feasibility of a motor-cognitive training program in patients after mild to severe traumatic brain injury in an acute hospitalization setting. The intervention is a step-based dual-task training, i.e. patients are presented with step patterns that they have to memorize and then execute in the tempo given by a metronome. Researchers will assess the feasibility of the motor-cognitive training regarding acceptance and safety, user evaluation of the training and training performance.

NCT ID: NCT06148324 Recruiting - Clinical trials for Traumatic Brain Injury

MENTOR Wellness Program

Start date: April 11, 2024
Phase: N/A
Study type: Interventional

This randomized trial aims to determine the effectiveness a virtual wellness intervention program in individuals with traumatic brain injury (TBI). Participants will be randomized at enrollment into two groups: immediate treatment (IT) and delayed treatment (DT) group. This study will also provide insights into the impact of these intervention's components in helping emotional, physical, and nutritional outcomes post-injury in the context of social determinants of health (SDOH).