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Trauma clinical trials

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NCT ID: NCT00830453 Completed - Stroke Clinical Trials

Hyperbaric Oxygen Therapy in Chronic Stable Brain Injury

HYBOBI
Start date: November 2003
Phase: Phase 2
Study type: Interventional

The purpose of this study is to discover the feasibility of conducting clinical research in individuals with chronic sequelae following brain injury who are given hyperbaric oxygen. This study will also look at the outcome of individuals with a chronic stable brain injury due to trauma, anoxia (lack of oxygen to the brain), or stroke, who are given hyperbaric oxygen. Outcome measures testing cognitive (memory, etc.) and functional (balance, strength, etc.) measures will be performed before the hyperbaric sessions, immediately following them, and 6 months later. The subject will receive 60 hyperbaric sessions, 60 minutes in the chamber, to a pressure of 1.5 ATA, once daily, Monday through Friday.

NCT ID: NCT00816738 Completed - Trauma Clinical Trials

Evaluation of the Treatment of Recurrent Corneal Erosions by Anterior Stromal Puncture With Nd: YAG Laser

Start date: January 2008
Phase: N/A
Study type: Observational

To evaluate the clinical outcomes in patients with recurrent corneal erosions who received anterior stromal puncture by use of neodymium:yttrium-aluminum-garnet (Nd:YAG) laser.

NCT ID: NCT00815243 Completed - Trauma Clinical Trials

Telemedicine Consultation in Trauma and Orthopedic

TeleTO
Start date: September 2007
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether telemedicine consultations (lead by standard scheme)allows to increase quality of anatomical and functional outcomes and improve clinical work-flow at patients with acute bone and joint trauma, hip pathology and congenital orthopedics abnormalities.

NCT ID: NCT00795535 Completed - Trauma Clinical Trials

Heart Rate Variability in Trauma Patients

HRV
Start date: May 2007
Phase: N/A
Study type: Observational

The purpose of this study is to develop new triage tool for trauma patients based on HRV. EKG will be prospectively measured in trauma patients in two locations: in the prehospital setting (the field and during transport by helicopter) and in the hospital setting. In each case HRV will be derived from the EKG signal, will be correlated with other non-invasive signals (e.g. near infrared spectroscopy (NIR), and bispectral EEG (BIS)), along with other routinely measured variables (blood pressure, respiratory rate, pulse oximetry, etc), will be correlated with injury severity and day of discharge. An algorithm will be constructed using multiple linear regression. The hypotheses are: 1. reduced HRV in the field correlates with bad outcome; 2. the specificity and efficiency of HRV as a screening tool can be improved by controlling factors such as heart rate, age, gender, respiratory rate, and pulse oxygen saturation; 3. an easy to interpret HRV index can be derived that can be used for trauma triage or diagnosis.

NCT ID: NCT00739076 Completed - Trauma Clinical Trials

Pain Control After Trauma

VRHTrauma
Start date: August 2007
Phase: N/A
Study type: Interventional

Using Virtual Reality as a form of pain control for trauma patients.

NCT ID: NCT00726128 Completed - Trauma Clinical Trials

Patient Outcomes Evaluation of the EBI Vuelock™ Anterior Cervical Plate System

VueLock
Start date: August 1998
Phase:
Study type: Observational

To prospectively collect radiographic and outcome data on patients who are having cervical spine fusion surgery with the VueLock™ Anterior Cervical Plate System

NCT ID: NCT00724035 Completed - Trauma Clinical Trials

Ultrasound-Guided Axillary or Infraclavicular Nerve Block for Upper Limb Surgery

Start date: May 2008
Phase: Phase 4
Study type: Interventional

This study aims to detect differences in onset time of brachial plexus (i.e., arm) anesthesia using two different nerve block techniques. Using ultrasound guidance, axillary (i.e., at the armpit) and infraclavicular (i.e., below the collarbone) blocks will be performed to patients undergoing upper limb surgery. The investigators will analyze how long it takes for anesthesia to be adequate for pain-free surgery, thus determine the optimal technique for this kind of surgery.

NCT ID: NCT00671489 Completed - Trauma Clinical Trials

Tachikawa Project for Prevention of Posttraumatic Stress Disorder With Polyunsaturated Fatty Acid (TPOP): TPOP-01 Study

Start date: May 2008
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of Polyunsaturated Fatty Acid for the prevention of Posttraumatic Stress Disorder (PTSD) in patients with accidental injuries.

NCT ID: NCT00671307 Completed - Infection Clinical Trials

Ascending Single Dose Study of Rhu-pGelsolin in Patients With Decreased Gelsolin Levels

Start date: March 2008
Phase: Phase 1/Phase 2
Study type: Interventional

This study is designed to assess the pharmacokinetics and safety of an infusion of a single dose of recombinant plasma gelsolin (rhu-pGelsolin) when given to patients admitted to the Intensive Care Unit with documented low levels of natural gelsolin. It is believed that this drug will raise the gelsolin levels in these patients and decrease the probability that they will develop complications from their underlying disease such as organ system failure or death.

NCT ID: NCT00671099 Completed - Trauma Clinical Trials

Tachikawa Project for Prevention of Posttraumatic Stress Disorder With Polyunsaturated Fatty Acid (TPOP): TPOP-02 Study

Start date: December 2008
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate efficacy and safety of Polyunsaturated Fatty Acid for the prevention of Posttraumatic Stress Disorder (PTSD) in patients with accidental injuries.