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Trauma clinical trials

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NCT ID: NCT05884593 Active, not recruiting - Trauma Clinical Trials

Analysis of Pedicle Screw Accuracy to Plan Using Medtronic Mazor Robotic System

Start date: March 5, 2021
Phase: N/A
Study type: Interventional

The purpose of the study is to assess screw deviation from pre-planned trajectory using the Mazor X robotic system in patients undergoing posterior thoracolumbar arthrodesis procedures between T2-S1.

NCT ID: NCT05873959 Active, not recruiting - Trauma Clinical Trials

An Observational Study to Evaluate the Safety and Efficacy of Humacyte's HAV for Arterial Replacement or Reconstruction in Ukrainian Patients With Life or Limb-threatening Vascular Trauma

Start date: May 31, 2023
Phase:
Study type: Observational

Humacyte provided HAVs as humanitarian aid to Ukraine. This retrospective observational study is designed to collect data from patients in whom the HAVs have already been implanted on a humanitarian basis between June 2022 and May 2023.

NCT ID: NCT05608577 Active, not recruiting - Trauma Clinical Trials

RE-BLEED: A Digital Platform for Identifying Bleeding Patients - a Feasibility Study

RE-BLEED
Start date: October 1, 2021
Phase:
Study type: Observational

The RE-BLEED feasibility study aims to develop and test a real-time digital platform, whereby bleeding patients in-hospital can be identified and approached for their consent to participate in future research studies.

NCT ID: NCT05544162 Active, not recruiting - Critical Illness Clinical Trials

Personalized Nutrition Delivery to Improve Resilience in Older Adult Trauma Patients

SeND Home
Start date: January 5, 2023
Phase: N/A
Study type: Interventional

This is a Pilot study designed to set up for an randomized clinical trial (RCT) comparing the SeND Home pathway to a standard of care nutrition delivery in critically ill older adult trauma patients. Subjects will be randomized 3:1 to either SeND Home precision nutrition pathway or control arm. Subjects randomized to the SeND Home arm will receive oral nutrition supplements (ONS) up to 3 times per day while in the hospital and for 4 weeks after discharge. Subjects in the standard of care arm will receive normal nutrition recommendations from their clinical providers. Participants in both groups will undergo non-invasive tests that measure how much energy (calories) they are using, body composition, and muscle mass.

NCT ID: NCT05530642 Active, not recruiting - Clinical trials for Major Depressive Disorder

An Augmented Training Program for Preventing Post-Traumatic Stress Injuries Among Diverse Public Safety Personnel

Start date: September 22, 2020
Phase: N/A
Study type: Interventional

Public safety personnel (PSP; e.g., border services personnel, correctional workers, firefighters, paramedics, police, public safety communicators) are frequently exposed to potentially psychologically traumatic events. Such events contribute to substantial and growing challenges from posttraumatic stress injuries (PTSIs), including but not limited to posttraumatic stress disorder. The PSP PTSI Study has been designed to evaluate an evidence-informed, proactive system of mental health assessment and training among Royal Canadian Mounted Police (www.rcmpstudy.ca) for delivery among diverse PSP (i.e., firefighters, municipal police, paramedics, public safety communicators). The training is based on the Unified Protocol for the Transdiagnostic Treatment of Emotional Disorders, adapted for PSP, and named Emotional Resilience Skills Training (ERST). The subsequent PSP PTSI Study results are expected to benefit the mental health of all participants and, ultimately, all PSP.

NCT ID: NCT05376462 Active, not recruiting - Trauma Clinical Trials

Quantra® System With the QStat® Cartridge in Trauma

Start date: April 12, 2022
Phase: N/A
Study type: Interventional

This is a prospective, single-center, controlled, open label, trial randomized in two parallel groups designed to assess the Quantra QStat System in trauma patients.

NCT ID: NCT05308303 Active, not recruiting - Trauma Clinical Trials

AI to Improve Data From Danish Cardiac Arrest Registry

Start date: June 1, 2022
Phase:
Study type: Observational

Out-of-hospital cardiac arrest is a leading cause of death worldwide and patient outcome vary substantially throughout regions suggesting further evaluation and potential for improvement.When focussing on subgroups of OHCA, data in certain areas remains scarce and the need of revised guidelines is evident. Furthermore, enhanced knowledge on these varieties of OHCA's apply to substantial number of patients, also among vulnerable populations. The Danish Emergency Medical System introduced a nationwide registry of electronic medical reports in 2016. This report system allows electronic searches and thereby the opportunity to identify subgroups of OHCA's. Thus, this novel reporting enables the evaluation of new characteristics of cardiac arrests of non-cardiac origin, in cases where an automated external defibrillator (AED) is retrieved but did not recommend defibrillation and finally in OHCA related to foreign body obstruction. With the advantages of artificial intelligence, this project will enhance and strengthen data from the Danish Cardiac Arrest Registry. It may substitute the manual validation of the around 9000 cases per year in Denmark. Further, it proposes improvement of quality and development of observational health research.

NCT ID: NCT05294575 Active, not recruiting - Trauma Clinical Trials

AI to Improve Outcome From Traumatic Cardiac Arrest

Start date: February 22, 2022
Phase:
Study type: Observational

This study evaluates data from patients in The Danish Medical Service electronical registry over a 6-year period from 2016 to 2021 with traumatic cardiac arrest. The objective of this study is to use artificial intelligence to evaluate reversible causes and relevant circumstances regarding traumatic OHCA in order to improve treatment and survival.

NCT ID: NCT05146700 Active, not recruiting - Trauma Clinical Trials

Restrictive vs. Liberal Oxygen in Trauma

TRAUMOX2
Start date: December 10, 2021
Phase: Phase 4
Study type: Interventional

Victims of trauma are often healthy individuals prior to the incident, but acquire numerous complications including sepsis and pulmonary complications and diminished quality of life after trauma. According to Advanced Trauma Life Support guidelines, all severely injured trauma patients should receive supplemental oxygen. The objective of TRAUMOX2 is to compare the effect of a restrictive versus liberal oxygen strategy the first eight hours following trauma on the incidence of 30-day mortality and/or major respiratory complications (pneumonia and acute respiratory distress syndrome) within 30 days (combined primary endpoint).

NCT ID: NCT05026788 Active, not recruiting - Covid19 Clinical Trials

Impact of COVID-19 Pandemic on Orthopaedic Practice

COVERT
Start date: March 17, 2020
Phase:
Study type: Observational

The COVERT Collaborative is led by a group of academic surgeons that is looking into the impact of the unprecedented COVID-19 pandemic on Trauma and Orthopaedic practice. This will involve both trauma and elective procedures, as well as mortality rates, operative and anaesthetic case mix. The information will help to shape service reconfiguration and enhance patient-specific treatment especially in the threat of potential subsequent waves and future pandemics.