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Syndrome clinical trials

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NCT ID: NCT05126563 Completed - Clinical trials for Post COVID-19 Syndrome

Randomized Double-Blind Phase 2 Study of Allogeneic HB-adMSCs for the Treatment of Chronic Post-COVID-19 Syndrome

HBPCOVID02
Start date: January 6, 2022
Phase: Phase 2
Study type: Interventional

This study will enroll up to 80 subjects with Chronic Post COVID-19 Syndrome. Subjects will receive four intravenous injections of either allogeneic HB-adMSC's or a placebo over 10 weeks with two follow-up visits and an end of study visit at week 26.

NCT ID: NCT05126043 Completed - Clinical trials for Acute Coronary Syndrome

Lipid Profile in Acute Coronary Syndrome

Start date: November 30, 2021
Phase:
Study type: Observational

This study aims to assess the TG/Hdl-c ratio in patients with acute coronary syndrome as a novel marker of atherosclerosis.

NCT ID: NCT05125419 Completed - Clinical trials for Acute Coronary Syndrome

Homocysteine in Acute Coronary Syndrome

Start date: November 30, 2021
Phase:
Study type: Observational [Patient Registry]

This study aims to determine the relation between high homocysteine levels and increased incidence of acute coronary syndrome in young patients

NCT ID: NCT05125263 Completed - Clinical trials for Patellofemoral Pain Syndrome

Effects of Kinesiotaping and Mulligan Tapping on PFPS

Start date: November 15, 2021
Phase: N/A
Study type: Interventional

The aim of this research is to compare the effects of kinesiotaping and mulligan taping on pain, hamstring flexibility, cadence and physical performance of lower limb in patients suffering from patellofemoral pain syndrome according to time duration 24, 48 and 72 hours. Randomized controlled trial done at Riphah International University Rawalpindi campus, Pakistan Railway Hospital and private clinics of twin cities. The sample size was 20. The subjects were divided in two groups, 10 subjects in kinesiotaping group and 10 in mulligan taping group. Study duration was 1 year. Sampling technique applied was non probability convenient sampling technique. Both males and females of 20-35 age bracket having anterior knee pain for more than 2 months and ≥3 pain on NPRS while performing activities i.e. ascending descending stairs, squatting and sitting for extending periods of time were included in study. Tools used in study are NPRS, Kujala pain rating sale, goniometer, active knee extension test, time up and go test.

NCT ID: NCT05124197 Completed - Pressure Ulcer Clinical Trials

Extended Prone Position Duration COVID-19-related ARDS: a Retrospective Study

Start date: March 1, 2020
Phase:
Study type: Observational

Prone position (PP) is standard of care for mechanically ventilated patients with severe acute respiratory distress syndrome in the intensive care unit (ICU). Recommendations suggest PP durations of at least 16 hours. In 2020, COVID-19 pandemic led to a great number of patients requiring mechanical ventilation and PP in the ICU. Risk of ICU staff viral contamination and work overload led to prolongation of PP duration up to 48 hours. Here investigators report outcomes of prolonged PP sessions in terms of skin complications (pression injuries) and ventilatory improvement.

NCT ID: NCT05120583 Completed - Clinical trials for Patellofemoral Pain Syndrome

Pilates-based Core Strengthening on Patellofemoral Pain Syndrome

Pilates
Start date: November 1, 2020
Phase: N/A
Study type: Interventional

Patellofemoral pain syndrome (PFPS) is one of the most common musculoskeletal pain conditions that tend to become a chronic problem. PFPS is common among young adolescents, particularly in physically active individuals aged 12 to 17 years old with more prevalence among females, as it affects females 1.5 - 3 times when compared to males.

NCT ID: NCT05120531 Completed - Down Syndrome Clinical Trials

Down Syndrome Autonomic Nervous System Induction Bradycardia

DANSIB
Start date: January 4, 2022
Phase:
Study type: Observational

Children with Down syndrome (DS) often experience dangerously low heart rates on induction of anesthesia for routine procedures and this occurs at 10 times the rate of non-DS patients. Given that the cardiac output of children is heart rate dependent, bradycardia is especially perilous in this population. Historically, individuals with DS were not expected to survive beyond childhood; consequently, correction of congenital anomalies, e.g. cardiac defects, was not frequently offered. Fortunately, today individuals with DS live into adulthood and surgical correction of anomalies is universally offered. Thus, increasing numbers of children with DS are exposed to anesthesia and at risk for this hemodynamic catastrophe. It is medically unacceptable and an autonomic nervous system mechanism will be sought.

NCT ID: NCT05117684 Completed - Clinical trials for Budd-Chiari Syndrome

To Compare "Balloon Occluded Thrombolysis" With "Conventional Catheter Directed Thrombolysis" in Thrombotically Occluded DIPSS Stent in Patients of Budd- Chiari Syndrome.

Start date: November 5, 2021
Phase:
Study type: Observational

DIPSS has become a widely accepted treatment for complications of portal hypertension. Shunt or hepatic vein stenosis are common short and mid term complications of the procedure. When identified early, shunt stenosis or occlusion may be treated before recurrence of the symptoms for which DIPSS was done at the first place. Present day endovascular DIPSS revision techniques have significantly improved the primary assisted patency rates. The purpose of this study is to understand the newer technique of Combined balloon occlusion thrombolysis and intra stent balloon sweeping being practiced at our institute and compare it with the widely used conventional thrombolytic methods.

NCT ID: NCT05115396 Completed - Clinical trials for Carpal Tunnel Syndrome

Effectiveness of Mirror Therapy in Patients With Carpal Tunnel Syndrome

Start date: December 1, 2021
Phase: N/A
Study type: Interventional

Carpal tunnel syndrome (CTS) is the most prevalent entrapment neuropathy. CTS presents with motor and sensory disturbances, including pain, paraesthesia, and numbness in the fingers and hand. Therefore, CTS has a great impact on the activities of daily living. There are non-surgical treatments that can be effective in people who experience mild or moderate symptoms derived from CTS. Among them, flexor tendon and median nerve sliding exercises may offer an improvement in pain severity and symptoms, strength, wrist joint range, functionality, and quality of life for people with CTS. However, there are few studies on the effectiveness of treatments focused on the mechanisms of neuroplasticity through techniques aimed at rehabilitating different deficits. Mirror therapy (MT) may be beneficial in musculoskeletal injuries that occur with pain and reduced functionality of a body segment. For example, in people with acute stroke, orthopaedic hand injuries or complex regional pain syndrome type 1. However, its effect has not been studied in patients with CTS in mild or moderate stages. Thus, the objective of this study is to analyze the effectiveness of MT with conventional CTS exercises in symptoms of median nerve compression, pain, mobility, strength and motor functionality in patients with CTS.

NCT ID: NCT05115318 Completed - Tourette Syndrome Clinical Trials

The Effect of Medical Cannabis on Tics, Premonitory Urge and Psychiatric Comorbidity in Adults With Tourette Syndrome

Start date: July 1, 2020
Phase:
Study type: Observational

Medical cannabis (MC) is a standard treatment in Israel to adults with resistant Gilles de la Tourette syndrome (GTS). While small randomized control trials assessed THC efficacy on tics and premonitory urge, only small retrospective studies assessed MC efficacy and tolerability in GTS. Herein, By using an open-label, prospective design, our aim is to determine the preferred method of use, efficacy and tolerability of 12 weeks of treatment with MC in adult patients with GTS.