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Surgery clinical trials

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NCT ID: NCT04469205 Terminated - Breast Cancer Clinical Trials

Study to Assess the Impact of Personalized Coaching on the Time Period and Quality of Return to Work After Breast Cancer

OPTICOACH
Start date: October 5, 2020
Phase: N/A
Study type: Interventional

Evaluate the impact of coaching sessions on the return to work rate (number of patients returning at work / total number of patients per arm) 6 months after inclusion in the study for breast cancer in professionnally active patients.

NCT ID: NCT04305379 Terminated - Prostate Cancer Clinical Trials

Augmented BLAdder NecK rEconstruction Trial for Improved Urinary Function After Radical Prostatectomy

BLANKET
Start date: January 16, 2020
Phase: N/A
Study type: Interventional

The investigators are conducting a prospective, randomized trial to investigate whether patients randomized to receive an augmented bladder neck reconstruction (aBNR) at the time of robotic-assisted laparoscopic prostatectomy experience improved urinary function post-operatively compared to patients who undergo prostatectomy with a standard BNR. An aBNR here consists of the autologous medial umbilical ligament sling as well as a bladder neck intussusception stitch. The standard BNR group will receive the intussusception stitch only.

NCT ID: NCT04294563 Terminated - Surgery Clinical Trials

Peanut Protein Supplementation to Prevent Muscle Atrophy and Improve Recovery Following Total Knee Arthroplasty

Start date: August 1, 2021
Phase: N/A
Study type: Interventional

This randomized controlled trial will study the effects of peanut protein supplementation on changes in muscle size and quality in patients undergoing total knee arthroplasty.

NCT ID: NCT04233073 Terminated - Surgery Clinical Trials

Trial of Andexanet in Patients Receiving an Oral FXa Inhibitor Who Require Urgent Surgery

Annexa-S
Start date: June 27, 2021
Phase: Phase 2
Study type: Interventional

Prospective, open-label clinical trial to evaluate the efficacy and safety of andexanet alfa patients who require urgent surgery that have been anticoagulated with the FXa (activated factor X) inhibitors.

NCT ID: NCT04198285 Terminated - Surgery Clinical Trials

Post-Operative Voiding After Gynecological Surgery Trial

POVAGS
Start date: January 10, 2020
Phase: N/A
Study type: Interventional

To determine whether partially filling the bladder after outpatient gynaecological laparoscopy expedites time to first void and discharge. Methods: A single site, single-blinded, randomized control trial in which eligible patients undergo partial retrograde bladder filling immediately post-operatively compared to bladder drainage and foley catheter removal. Primary outcome is time to first void, secondary outcomes include time to discharge, post-operative complications and patient satisfaction.

NCT ID: NCT04105738 Terminated - Surgery Clinical Trials

Voice Analysis as a Predictor for Difficult Intubations

Start date: March 28, 2017
Phase:
Study type: Observational

To investigate if signal processing can detect subtle changes in speech production clinically relevant to oropharynx anatomy that may provide an objective measure in the assessment of the presumed difficulty of intubation.

NCT ID: NCT04101006 Terminated - Surgery Clinical Trials

Perioperative Changes of Cerebrovascular Autoregulation and Association With Cognitive Function

Start date: April 14, 2016
Phase:
Study type: Observational

Cerebral blood flow is tightly regulated to ensure constant cerebral perfusion independently from systemic blood pressure fluctuations. This mechanism is termed cerebrovascular autoregulation and preserves adequate cerebral perfusion in a range between 50 and 150 mmHg of cerebral perfusion pressure. Upper and lower autoregulatory limits may vary individually. Beyond the autoregulatory range the protective autoregulatory response is lost, facilitating cerebral ischemia or hyperemia. The cerebrovascular response may be altered during general anesthesia, through direct effects of anesthetic agents on the vascular tone, changes of arterial partial pressure of carbon dioxide or the administration of vasoactive substances. The association of perioperative impairment of cerebral autoregulation and postoperative cognitive function has been discussed controversially.

NCT ID: NCT04097795 Terminated - Colorectal Cancer Clinical Trials

Incremental Cost-Utility Study on Prehabilitation Among Older Patients With Colorectal Cancer Undergoing Surgery

PreColo CU
Start date: July 1, 2019
Phase:
Study type: Observational

A prospective multicenter observational cost-utility study following older or high-risk patients with colorectal cancer with and without prehabilitation before surgery.

NCT ID: NCT03962036 Terminated - Surgery Clinical Trials

Effect of One-lung Ventilation on BIS Values

Start date: October 11, 2019
Phase:
Study type: Observational

In this observational study, all enrolled patients having a thoracic surgical procedure requiring lung isolation will have a bispectral index (BIS) monitor placed at time of induction. BIS monitors are used to assist in determining depth of anesthesia. This study will evaluate changes in BIS before, during and after lung isolation.

NCT ID: NCT03957525 Terminated - Anxiety Clinical Trials

Pediatric Preoperative Virtual Reality Program

PPVRP
Start date: August 1, 2019
Phase: N/A
Study type: Interventional

Does the introduction of a preparatory virtual reality (VR) program that is used in the home environment, have an effect on the anxiety level of children immediately before surgery, prior to administration of preoperative sedatives?