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Surgery clinical trials

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NCT ID: NCT05801679 Recruiting - Surgery Clinical Trials

Evaluating Outcomes in Cardiac Surgery Patients Who Receive Sugammadex vs. Placebo

Start date: July 3, 2023
Phase: Phase 3
Study type: Interventional

This is a prospective randomized blinded controlled trial that will enroll 175 subjects undergoing cardiopulmonary bypass at NorthShore University HealthSystem. The purpose of this study is to compare clinical outcomes in elective and urgent cardiac surgical patients at NorthShore University HealthSystem when receiving sugammadex, a common neuromuscular blockade reversal drug given after surgery and before the breathing tube is removed vs. those patients who do not receive sugammadex (placebo) group. The Investigators will compare the following outcomes in both the sugammadex and placebo groups during patients hospital stay: # of patients who have the breathing tube removed within 6 hour of the end of surgery, time it takes to remove the breathing tube after surgery, ICU and hospital length of stay, cost of the ICU stay, time to achieve a train of four ratio of > or equal to 0.9, whether patients develop pneumonia or not, whether they require the breathing tube to be replaced during their hospital stay and to compare the nursing perception of patients recovery within first 24 hours of their ICU stay.

NCT ID: NCT05798585 Active, not recruiting - Surgery Clinical Trials

Comparing Erector Spinae Plane (ESP) and Thoracic Paravertebral (TPV) Block Analgesic Effect After Elective VATS

Start date: March 31, 2023
Phase: N/A
Study type: Interventional

The aim of the study is to compare two different locoregional techniques in VATS.

NCT ID: NCT05797194 Completed - Surgery Clinical Trials

The Association Between SIRI and POD in Older Patients

Start date: March 1, 2019
Phase:
Study type: Observational

Postoperative delirium (POD) remains one of most common complication in elderly patients receiving surgery, which is characterized by acute and fluctuating change in the level of cognition and consciousness. Previous studies have shown that surgery and anesthesia-induced acute peripheral inflammation and neuroinflammation may lead to delirium after surgery. Systemic Inflammation Response Index (SIRI) is a more easily accessible and comprehensive inflammation marker derived from monocyte, neutrophil, and lymphocyte count, which has been investigated to assess the prognosis of cancer and infectious diseases. However, the relationship between SIRI and POD has yet to be investigated.

NCT ID: NCT05797064 Not yet recruiting - Surgery Clinical Trials

Establishment of a Feasibility Model for NOSE Surgery Based on Machine Learning

Start date: June 1, 2023
Phase:
Study type: Observational

The goal of this observational study is to test in patients with resectable rectosigmoid cancers. The main question it aims to answer is establishment of a feasibility model for predicting natural orifice specimen extraction surgery (NOSES) based on machine learning.

NCT ID: NCT05796830 Not yet recruiting - Quality of Life Clinical Trials

Determination of the Effect of Puzzle Use in Elderly Patients

Start date: March 28, 2023
Phase: N/A
Study type: Interventional

The aim of this study is to determine the effects of the use of a simple, reliable and cost-effective puzzle on post-operative cognitive function changes, postoperative recovery, and quality of life using questionnaires and face-to-face interview techniques.

NCT ID: NCT05795127 Active, not recruiting - Surgery Clinical Trials

Risk for Reoperation After First MTP Joint Arthrodesis

Start date: October 1, 2022
Phase:
Study type: Observational

We will screen all first metatarsophalangeal joint arthrodeses performed between 2010 and 2022 in Helsinki University Hospital. Information about demographics and additional diagnoses will be yielded from data pool of medical records. Additionally we review pre- and post-operative x-rays for first MTP joint angles and OR records for operative techniques. Our aim is to find associations between those known variables and risk for reoperation in two years after operation.

NCT ID: NCT05794269 Recruiting - Quality of Life Clinical Trials

Turkish Version of the QoR-15 for Emergency Laparotomy

QoR-15T-EL
Start date: February 1, 2023
Phase:
Study type: Observational

Patient perceived quality of recovery is an important outcome after surgery and should be measured in clinical trials. The QoR-15 was designed to measure quality of recovery postoperatively. It provided an efficient evaluation of the postoperative quality of recovery. The primary objectives of this study is validate the Turkish version of QoR-15 questionnaire for emergency laparotomy. The investigators will test its validity, reliability, responsiveness, and clinical acceptability and feasibility, with patients emergency laparotomy, in the University of Health Sciences, Gülhane Education and Training Hospital Ankara, Türkiye.

NCT ID: NCT05785013 Completed - Surgery Clinical Trials

The Impact of Preoperative Supplementation of Zinc

Start date: April 1, 2023
Phase: N/A
Study type: Interventional

1. Pre operative anthropometric assessment including : weight in kg, height/length and BMI 2. Pre operative Zinc supplementation (dose according to the age) for 7 days preoperatively for cases 3. Postoperative data collection

NCT ID: NCT05782686 Recruiting - Breast Cancer Clinical Trials

Impact of Systematic Shaving on Margins

Start date: October 7, 2020
Phase: N/A
Study type: Interventional

The objective of this clinical trial is to demonstrate the reduction of positive margins in the definitive pathology of patients undergoing breast-conserving surgery with the systematic shaving technique compared to conventional surgery, and the reduction of second interventions for margin enlargement.

NCT ID: NCT05782504 Recruiting - Breast Cancer Clinical Trials

Patient-centered Breast Cancer Teleprehabilitation

BC-PREHAB
Start date: January 30, 2023
Phase: N/A
Study type: Interventional

Surgery, the cornerstone of most cancer treatments, is associated with considerable postoperative complications. Adjusting patients' health behavior before surgery may have beneficial effects on postoperative outcomes. Women (n=50) who will undergo breast surgery because of stage I-III breast cancer are eligible. All participants will receive multimodal patient-centered teleprehabilitation comprising of motivational interviewing, education, exercise therapy, and stress management.