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Surgery clinical trials

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NCT ID: NCT05863013 Enrolling by invitation - Quality of Life Clinical Trials

Use of the ADL-Glittre Test in the Pre and Postoperative Period of Patients With Lung Cancer

Start date: June 13, 2023
Phase: N/A
Study type: Interventional

Lung cancer is the most common type of cancer and the leading cause of cancer death worldwide, in both men and women. Improvements in earlier preoperative staging and more effective adjuvant treatment have improved survival in non-small cell lung cancer, although surgical resection remains the mainstay of care for all patients in stages I to IV. This study proposes to evaluate the functional capacity through TGlittre in patients with non-small cell lung cancer, before and after thoracic surgery, taking into account the predictive role of this test in the risk of complications and in the evaluation of the impact of functional rehabilitation.

NCT ID: NCT05828680 Enrolling by invitation - Clinical trials for Cardiovascular Diseases

Circadian Rhythm Disruption in the Hospital Intensive Care Environment

Start date: March 15, 2023
Phase:
Study type: Observational

Abrupt changes to one's lifestyle disrupt biorhythms. Acute effects are well known from jet lag where transmeridian travel leads to insomnia, fatigue, irritability, gastrointestinal symptoms and other complaints. Several studies in the hospital environment reported dampened and misaligned biorhythms, suggesting that the inpatient experience is replete with circadian disruptors. However, comprehensive assessments of how circadian clocks are affected in intensive care and how this predicts post-operative recovery and risk are largely missing.

NCT ID: NCT05699343 Enrolling by invitation - Surgery Clinical Trials

Surgical Treatment of Peri-implantitis Using a Bone Substitute With or Without a Resorbable Collagen Membrane

Start date: January 30, 2023
Phase: N/A
Study type: Interventional

The objective of the present randomized clinical trial will be to compare two surgical methods of treating peri-implantitis. This study will determine if surgical debridement of peri-implantitis bone defects, including air decontamination of implant surfaces, in combination with the placement of a bone graft, differs in treatment outcomes compared to placing the same bone graft material with a resorbable collagen membrane placed over the bone graft.

NCT ID: NCT05690633 Enrolling by invitation - Surgery Clinical Trials

Feasibility of Obtaining Pulse Oximetry Readings From the Oropharynx

Start date: January 9, 2024
Phase: N/A
Study type: Interventional

This is a prospective study to evaluate the feasibility of obtaining a pulse oximetry ready from the oropharynx with a standard oximeter probe that has been attached to an oral airway or a tongue blade. The study will compare the values from the peripheral pulse oximeter on a finger, toe, foot or hand with the that from the oropharyngeal oximeter. The study will also compare the saturation from an arterial blood gas (ABG) collected as standard of care with that obtained from the oropharyngeal oximeter.

NCT ID: NCT05670756 Enrolling by invitation - Surgery Clinical Trials

Preoperative Survey to Evaluate Patient Allergy

Start date: May 1, 2023
Phase:
Study type: Observational

The study will only involve identification of the listed allergies from the electronic medical record and investigation into the symptoms that prompted this allergy listing. The purpose is to evaluate demographics and prevalence of allergies in patients presenting for surgery, evaluate the medical decision making process behind allergy identification, and determine its potential impact on perioperative care. The participants will be asked to complete a survey in REDCap using an iPad during the visit.

NCT ID: NCT05612477 Enrolling by invitation - Clinical trials for Hepatocellular Carcinoma

Blood Salvage in Orthotopic Liver Transplantation With HCC

SOLT
Start date: January 21, 2023
Phase: N/A
Study type: Interventional

This single-centre randomized pilot study will investigate the feasibility, safety, and efficacy of IBSA (intraoperative blood cell salvage and autotransfusion -when a patient's own blood is collected from the surgical field, washed, and transfused back to them), in patients undergoing Liver transplantation for Hepatocellular carcinoma (HCC). A total of 30 patient participants will be enrolled. A participant will be randomized only if enough blood is collected during the transplant surgery to produce a minimum of 1 unit of autologous blood. Patients will be randomized to receive their blood back (via transfusion) or have their own blood discarded. Patients will be followed after surgery for evaluation of safety and efficacy. Depending on the outcomes of this feasibility trial, a subsequent larger full-scale multi-institutional trial will be planned, which will be more appropriately powered to evaluate the true impact of IBSA on the use of allogeneic blood products and post-transplant HCC-specific outcomes.

NCT ID: NCT05569980 Enrolling by invitation - Quality of Life Clinical Trials

The Nordic Rectal Prolapse Study

NORDIC
Start date: April 1, 2023
Phase:
Study type: Observational

The goal of this observational study is to gather data about surgical procedures for rectal prolapse in adult human subjects. The main question it aims to answer is: • Which procedure is best for treating external rectal prolapse? Participants will: - be included if they can consent to participation - be offered standard care treatment, as no interventions will be done - be asked to answer relevant questionnaires within 3 months prior to the surgery for rectal prolapse - be asked to answer the same questionnaires 6 and 12 months postoperative - optionally answer the questionnaires again at 3 and 1 year postoperative, but this is not part of the existing funding body

NCT ID: NCT05534490 Enrolling by invitation - Surgery Clinical Trials

Surgery and Functionality in Older Adults

SFO
Start date: September 6, 2022
Phase: N/A
Study type: Interventional

When the literature is examined, it has not been found that the use of massage applications in relation to the functional level of individuals who have undergone abdominal surgery. We think that our study will be the first in this field. Therefore, this study will lay the groundwork for future studies on the subject. In the future, it is aimed to establish a standardized evaluation method to determine the functional levels of individuals who have undergone abdominal surgery and to determine the ideal duration and frequency when a decision is made to apply foot massage in the future with the data obtained as a result of this method. In this study, the effectiveness of foot massage on the functional level of individuals with high post-surgical kinesiophobia will be investigated.

NCT ID: NCT05441579 Enrolling by invitation - Surgery Clinical Trials

Recruitment and Behavioral Economic Strategies

Start date: May 17, 2022
Phase: N/A
Study type: Interventional

To determine the impact of the application of behavioral economic strategies on recruitment of pediatric patients into a randomized clinical trial assessing the impact of technology-based interventions on postoperative pain management.

NCT ID: NCT05386901 Enrolling by invitation - Surgery Clinical Trials

The Effects of Individualized Lung-protective Ventilation With Lung Dynamic Compliance-guided Positive End-expiratory Pressure(PEEP) Titration on Postoperative Pulmonary Complications of Pediatric Video-assisted Thoracoscopic Surgery

PEEP
Start date: June 10, 2022
Phase: N/A
Study type: Interventional

This study evaluates the influence of individualized lung-protective ventilation strategy(LPVS) on postoperative pulmonary complications(PPCs) through a randomized controlled trial when children undergoing thoracoscopic surgery with one-lung ventilation(OLV).The investigators evaluate the impact of using lung dynamic compliance-guided Positive End-expiratory Pressure(PEEP) versus conventional PEEP on a pressure-controlled ventilation(PCV).The researchers also analyzed perioperative vital signs and respiratory indicators of these LPVS.