"Carotid Web Incidence and Radiological Classification, Determination of Its Relationship With Ischemic Stroke"

Stroke Clinical Trial

Official title:

"The Incidence of Carotid Web and Its Radiological Classification, Determination of Its Relationship With Ischemic Stroke by Evaluating the Clinical Data and Vascular Risk Factors of Carotid Web Cases"

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT06058507
• Other study ID #: SDUWEB
• Status: Completed
• Start date: April 19, 2022
• Est. completion date: August 20, 2023

Study information

• Verified date: September 2023
• Source: Suleyman Demirel University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

In our research, we aim to increase awareness on this issue by classifying the frequency of carotid webs and their radiological classification; Evaluating the clinical data and vascular risk factors of carotid web cases and determining their relationship with ischemic stroke and determining the measures that can be taken for future optimal treatment.

We aimed to contribute to their approach.

Description:

Carotid web is a thin membrane-like tissue that extends from the wall to the lumen of the carotid artery bulb, identified radiologically. It is considered that stroke may be related to altered hemodynamics, blood stasis and fibrin-based clot embolization mechanisms in the distal carotid web. Radiologically, in DSA and CTA, there is a thin membrane-like intraluminal filling defect extending along the posterior carotid wall in oblique-sagittal sections and a corresponding defect in axial sections.

It is seen as a thin septum; There is no study on its classification in the literature. Determination of the incidence of carotid web, determination of its relationship with ischemic stroke / TİA, Facilitating distinctions such as dissection etc. by making radiological classification is important in terms of increasing awareness on this issue and early diagnosis. Demonstrating the relationship between carotid webs, which are shown as a cryptogenic cause of stroke, and vascular risk factors and taking protective measures against them will be effective in preventing strokes. In our research, we aim to increase awareness on this issue by classifying the frequency of carotid webs and their radiological classification; We aimed to evaluate the clinical data and vascular risk factors of carotid web cases, determine their relationship with ischemic stroke, and determine the precautions that can be taken to contribute to future optimal treatment approaches.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 31
• Est. completion date: August 20, 2023
• Est. primary completion date: July 20, 2023
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Being over 18 years old

• Having a preliminary diagnosis of cerebrovascular disease

• Having carotid CTA and/or DSA imaging performed

Exclusion Criteria:

• Being under 18 years of age

• Patients who cannot undergo CTA and/or DSA imaging due to the risk of contrast material allergy or renal failure.

• Patients for whom consent for imaging cannot be obtained by the patient and their relatives and for whom CTA/DSA examination is not required in terms of etiology

Related Conditions & MeSH terms

• Carotid Artery Diseases
• Ischemia
• Ischemic Attack, Transient
• Ischemic Stroke
• Stroke
• Transient Ischemic Attack

Intervention

Diagnostic Test:
• CT angiography
No intervention was made

Locations

Country	Name	City	State
Turkey	Suleyman Demirel University	Isparta

Sponsors (1)

Lead Sponsor	Collaborator
Suleyman Demirel University

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	ischemic stroke	dysarthria, weakness, facial paralysis	1 year
Secondary	transient ischemic atack	temporary weakness and slurred speech	1 year