Stroke, Ischemic Clinical Trial
Official title:
Changes in PERFusion and Cerebrovascular Reactivity Through Aerobic EXercise Training After Ischemic Stroke - a Proof of Concept Randomized Controlled Trial
Large cerebral vessel occlusion is a common phenomenon in the general population and accounts for 13-35% of ischemic strokes. Chronic stenosis in the large cerebral arteries is associated with cerebral hypoperfusion, cognitive decline and an increased risk of stroke or recurrent stroke, respectively. Even with upgrowth of surgical or endovascular interventions, mechanical reopening of the occluded vessels is often not possible. Alternative treatment opportunities include minimal-to-moderate blood pressure elevation (typically by ceasing antihypertensives) waiting for collateral circulation to develop spontaneously. Another conservative approach to increase cerebral perfusion is aerobic exercising. Physical activity has shown to lead to cerebral blood flow increase, especially in activated brain areas of healthy human and rat models. However, it is remains unknown, how physiological adaptation to physical activity expresses in persons after stroke due to large vessel occlusion. Herein, it is hypothesized that aerobic exercise facilitates the development of an extensive and functional vascular collateral network in persons with ischemic stroke and perfusion compromise.
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT03993236 -
Study on Rosuvastatin+Ezetimibe and Rosuvastatin for LDL-C Goal in Patients With Recent Ischemic Stroke
|
Phase 4 | |
| Completed |
NCT04069767 -
Innovative Physiotherapy in Stroke Rehabilitation
|
N/A | |
| Recruiting |
NCT06342206 -
The Assessment of Acute /Chronic Phase in Patients With Ischemic Cerebral Stroke Using TCM Diagnostic Tools
|
||
| Recruiting |
NCT03605381 -
MORbidity PRevalence Estimate In StrokE
|
||
| Enrolling by invitation |
NCT04956211 -
Periodontal Treatment and Ischemic Stroke
|
N/A | |
| Active, not recruiting |
NCT05098236 -
Effect of Visual Retraining on Visual Loss Following Visual Cortical Damage
|
N/A | |
| Completed |
NCT03942588 -
High-intensity Interval Training After Stroke
|
N/A | |
| Recruiting |
NCT04949334 -
Effects of Respiratory Muscle Training in Patients With Acute Ischemic Stroke
|
N/A | |
| Terminated |
NCT04095767 -
Assessing Safety and Performance of the ANA Catheter System, Combined With a Stent Retriever in Acute Ischemic Stroke
|
N/A | |
| Not yet recruiting |
NCT06352086 -
Understanding Visual Processing After Occipital Stroke
|
||
| Withdrawn |
NCT04991038 -
Clinical Investigation to Compare Safety and Efficacy of DAISE and Stent Retrievers for Thrombectomy In Acute Ischemic Stroke Patients
|
N/A | |
| Completed |
NCT01937182 -
The Efficacy of Citalopram Treatment in Acute Stroke
|
Phase 2 | |
| Completed |
NCT03649295 -
Combined Conventional Speech Therapy and Functional Electrical Stimulation in Dysphagia Following Stroke
|
N/A | |
| Recruiting |
NCT05303649 -
Effects of Neuronavigated Theta Burst Stimulation in Therapy of Post-stroke Aphasia
|
N/A | |
| Completed |
NCT04233515 -
Use of Oral Anticoagulants and Symptoms in Patients With Atrial Fibrillation in Örebro County
|
||
| Completed |
NCT05102877 -
Sensory Versus Motor Level Neuromuscular Electrical Stimulation
|
N/A | |
| Completed |
NCT04089917 -
A Study of the Use of the Q Aspiration Catheter to Remove Clot in Stroke Patients
|
||
| Completed |
NCT05221112 -
Effects of PNF Patterns Training on Trunk Balance, and Gait in Chronic Stroke Patients
|
N/A | |
| Not yet recruiting |
NCT05035953 -
Thrombolysis Combined With Edaravone Dexborneol on Hemorrhagic Transformation for Acute Ischemic Stroke
|
Phase 2 | |
| Completed |
NCT06326801 -
Resistive Diaphragmatic Breathing Exercise With Pursed Lips Breathing Exercise in Sub-acute Stroke Patients
|
N/A |