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Stroke, Acute clinical trials

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NCT ID: NCT00623350 Completed - Stroke, Acute Clinical Trials

Stroke DOC Arizona TIME - Stroke Team Remote Evaluation Using a Digital Observation Camera

Start date: December 2007
Phase: N/A
Study type: Interventional

Noninvasive prospective multi-center study of an interactive 2-way, wireless or site-independent, audiovisual telemedicine system designed for real-time remote examination of acute stroke symptoms and deficits as a basis for treatment consultation and recommendation. Study aims (1) to determine the impact of a site-independent, remote, telemedicine consultation system on decision making in the Emergency Department, regarding the decision to treat or not to treat with thrombolytics; (2) to assess the numbers of patients who receive thrombolytics and the time to treatment in patients evaluated by telemedicine versus telephone only; (3) to assess the appropriateness of thrombolytic treatment decisions in telemedicine versus telephone-only consultations; and (4) to assess the completeness of the data collection in telemedicine versus telephone-only consultations. 60 patients in Arizona with acute presentation of stroke symptoms, per bedside practitioner discretion (onset generally less than 12 hours and likely less than 3 hours) Two arms: Video Camera/Telemedicine (Intervention n = 30) and No Video Camera/Telephone only (Control n = 30)

NCT ID: NCT00604630 Completed - Stroke, Acute Clinical Trials

Multicenter Efficacy Study of Recombinant Human Erythropoietin in Acute Ischemic Stroke

ESS
Start date: January 2003
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this randomized, double-blind, placebo-controlled multicenter study is to determine in a cohort of 506 patients with acute ischemic stroke in the middle cerebral artery territory, the effect of a three-day high-dose, intravenous erythropoietin treatment on functional outcome up to a follow-up of 90 days.

NCT ID: NCT00565045 Completed - Stroke Clinical Trials

Treatments for Recovery of Hand Function in Acute Stroke Survivors

Start date: July 2007
Phase: Phase 1/Phase 2
Study type: Interventional

Impaired hand function is one of the most frequently persisting consequences of stroke. The purpose of this study is to investigate whether two different types of treatment improve recovery of hand function after stroke.

NCT ID: NCT00535197 Completed - Stroke, Acute Clinical Trials

Autologous Bone Marrow Stem Cells in Ischemic Stroke.

Start date: September 2007
Phase: Phase 1/Phase 2
Study type: Interventional

The aim of the study is to determine the safety and tolerability of an autologous CD34+ subset bone marrow stem cell infusion into the middle cerebral artery in patients who have suffered acute total or partial anterior circulation syndrome (TACS/PACS).

NCT ID: NCT00276380 Completed - Stroke, Acute Clinical Trials

A Study on the Use of Tanakan® for Recovery of Neurological Impairment Following Ischaemic Stroke

Start date: February 2003
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the effectiveness of Tanakan® 240mg in association with Acetylsalicylic acid (325mg/day) in the recovery of neurological impairment following ischemic stroke.

NCT ID: NCT00142792 Completed - Stroke Clinical Trials

Functional Electrical Stimulation (FES) for Upper Extremity Recovery in Stroke

Start date: December 2005
Phase: N/A
Study type: Interventional

Stroke is the leading cause of activity limitation among older adults in the United States. NeuroMuscular Electrical Stimulation (NMES) can assist stroke survivors in regaining motor ability and decreasing activity limitation caused by stroke. This study will research the effects of two types of NMES on reducing motor impairment and activity limitation.

NCT ID: NCT00132509 Terminated - Stroke, Acute Clinical Trials

FRALYSE Trial: Comparison of the Classical Rt-PA Procedure With a Longer Procedure in Acute Ischemic Stroke

Start date: September 2001
Phase: Phase 2
Study type: Interventional

Data from the literature have suggested that a longer time of thrombolysis might be more effective in ischemic stroke. We, the investigators at Hospices Civils de Lyon, have designed a randomized protocol to test this hypothesis. Moreover, the therapeutic window is 7 hours. Rt-PA (alteplase) is injected intravenously in the 2 arms of the study for a duration of 60 minutes in the arm with a "classical dose" and 90 minutes in the arm with a "low dose-longer infusion". This is a study of the outcome at 90 days.

NCT ID: NCT00123305 Completed - Stroke, Acute Clinical Trials

Intravenous Administration of Microplasmin for Treatment of Acute Ischemic Stroke

Start date: October 2005
Phase: Phase 2
Study type: Interventional

The primary purpose of this study is to evaluate the safety and preliminary efficacy of microplasmin when administered intravenously to patients who have suffered an acute stroke within 12 hours before randomization.

NCT ID: NCT00111852 Completed - Stroke, Acute Clinical Trials

Study of Desmoteplase (International Nonproprietary Name [INN]) in Acute Ischemic Stroke (DIAS-2)

Start date: April 2005
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate desmoteplase (which is a manufactured protein derived from the saliva of the vampire bat) in dissolving clots that are blocking the flow of blood through one (or more) of the blood vessels supplying the brain, thereby reopening the blocked blood vessel and allowing blood to flow again in individuals suffering from ischemic stroke.

NCT ID: NCT00061022 Completed - Stroke, Acute Clinical Trials

Safety and Effectiveness of NXY-059 for the Treatment of Patients Who Have Suffered From a Stroke

Start date: May 2003
Phase: Phase 3
Study type: Interventional

This study will determine if NXY-059 will improve recovery from an acute stroke. The study is designed to look at both overall recovery and recovery of motor function, for example muscle strengthen and coordination.