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Stress, Psychological clinical trials

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NCT ID: NCT02912780 Recruiting - Clinical trials for Inflammatory Bowel Diseases

Introduction of Microsystems in a Level 3 Neonatal Intensive Care Unit

Start date: January 2013
Phase: N/A
Study type: Observational

The advancement in life-saving technologies and clinical expertise in the care of extremely premature infants, have resulted in the development of large neonatal intensive care units (NICU). It has been suggested that reconstruction of megaunits of neonatal intensive care to smaller care units with specific patient population and clinical team providers will be essential to maintain optimal teamwork, quality of care and patient outcome. Despite the growing knowledge around the need for reconstruction of large NICUs to smaller units of care, there is no evidence regarding the safety and efficacy of microsystem model of care on the key aspects of health care. At the McMaster Children's Hospital (MCH), we planned a change from standard model of care to the microsystem model of care and therefore we aimed to prospectively assess the effect of this organizational change on the variable aspects of health care. A working group met weekly to formulate the implementation planning, to review the adaptation and adjustment process and to ascertain the quality of implementation following the initiation of the microsystem model. The study was retrospectively registered.

NCT ID: NCT02867657 Recruiting - Inflammation Clinical Trials

Bringing the Practice of Mindfulness Into Nature - Preventing Mental Fatigue in Healthcare Professionals.

Start date: June 2016
Phase: N/A
Study type: Interventional

The purpose of the study is to determine whether a five day mindfulness retreat in nature can increase measures of attention and self-compassion, and reduce stress among bachelor students at Danish Universities and University Colleges. Secondary whether the expression of inflammatory markers can be reduced . It is the hypothesis that perceived stress is reduced and the expression of genetic markers of inflammation is reduced after a five day mindfulness retreat.

NCT ID: NCT02621216 Recruiting - Clinical trials for Coronary Heart Disease

Tilburg Health Outcomes Registry of Emotional Stress in Coronary Intervention

THORESCI
Start date: December 4, 2013
Phase:
Study type: Observational [Patient Registry]

Background of the study: Percutaneous coronary interventions (PCI) have become mainstay treatment for acute coronary artery disease and the number of patients receiving PCI is vastly growing. However, relatively little long-term follow-up studies of large real-world clinical samples exist that have looked at the real-world effects of PCI treatment and adherence to current guidelines. Psychological risk factors are important in determining prognosis after PCI, and undergoing PCI may increase the risk of low mood. To date, studies have examined single psychological risk factors, without taking into account their relatedness. Moreover, guidelines are advocating psychosocial screening in early cardiovascular disease, but the screening test as proposed in the prevention guideline has not yet been validated or tested. Although the detrimental effects of psychological risk factors on cardiovascular prognosis are known, the mechanisms through which they exert these effects are yet unclear. It is to be expected that not one but multiple biological (inflammation, endothelial dysfunction) and behavioural (coping styles, poor self-care, consultation behaviour) pathophysiological processes play a role, and that these processes interact with each other. In PCI patients the mechanisms linking psychological risk to poor prognosis are still to be investigated. Objective of the study: 1. To examine the adherence to the prevention and PCI guidelines and the effects thereof on long term prognosis in PCI patients. 2. To evaluate the effectiveness of the psychosocial screening instrument of the European Society of Cardiology Prevention guideline 2012. 3. To examine effects of clustering psychological risk factors on several networks of potentially mediating mechanisms and long term outcomes in a large sample of PCI patients.

NCT ID: NCT02433431 Recruiting - Mindfulness Clinical Trials

Mechanisms of Mindfulness and Stress Resilience: A Mobile App Mindfulness Training Study

Start date: February 2015
Phase: N/A
Study type: Interventional

The purpose of this study is to test the active components of mindfulness meditation for reducing psychological stress and improving biomarkers of health. This study compares the effects of three brief trainings: (1) training in both present-moment attention and mindful acceptance, (2) training in present-focused attention, and (3) an active psychological training with no mindfulness content.

NCT ID: NCT02432339 Recruiting - Clinical trials for Psychological Stress

Effects of an Immunosuppressant Mycophenolate Mofetil or MMF on the Urinary Sodium Excretion Response to Mental Stress

MMF
Start date: April 22, 2014
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to determine if stopping the stress induced increase in inflammation will prevent sodium retention which in turn increases blood pressure. Each subject will test two separate times. One week, they will be taking a daily dose of mycophenolate mofetil (MMF), the other week they will be taking a placebo.

NCT ID: NCT02386293 Recruiting - Obesity Clinical Trials

Effectiveness of Avapro in Obese Normotensive/Hypertensive African Americans

Avapro3
Start date: April 2014
Phase: Phase 2
Study type: Interventional

The purpose of this study is to test the hypothesis that hypertension increases the anti-natriuretic effects of an angiotensin receptor antagonist during mental stress in overweight/obese African-American's who retain sodium during mental stress.

NCT ID: NCT02135250 Recruiting - Clinical trials for Theraphy of Chinese Traditional Medicine

Study on Therapeutic Effect of Treating Mental Stress Induced Myocardial Ischemia

Start date: January 2014
Phase: N/A
Study type: Interventional

This study aims to discuss whether the combined treatment of traditional Chinese medicine (TCM) and western medicine for Mental Stress Induced Myocardial Ischemia (MSIMI) does effect, namely the conventional therapy for Coronary Heart Disease( CHD) combining with TCM - Xinkeshu tablets.

NCT ID: NCT01544439 Recruiting - Clinical trials for Musculoskeletal Diseases

Occlusal Splint and Counseling to Temporomandibular Disorder

Start date: March 2012
Phase: Phase 3
Study type: Interventional

The aim of this study was to evaluate the effectiveness of the splint occlusal associated with counseling in reducing pain in patients with temporomandibular disorders, under the assumption that the occlusal appliance offers the highest rates of improvement than their placebo.

NCT ID: NCT01367379 Recruiting - Clinical trials for Psychological Stress

The Effect of the Duty Loading on the Stress Response of Physician

Start date: June 2011
Phase: N/A
Study type: Observational

The investigators will study in the possibility of cardiovascular disease, caused by the duty loading, of physician of internal medicine. The investigators will also explore if there {dose response effect} between the duty loading and the stress response of physicians of internal medicine. Therefore, the investigators will compare the stress responses of physicians of internal medicine during with different duty loading ( non-duty day, one duty area with 3 wards, 2 duty areas with 6 wards) in a observational method. Those stress response will be measured by cardiovascular risk indicators, including blood pressure, heart rate variability, blood sampling and urine sampling.