Comparison Between Unihemispheric and Bihemispheric TCDS in Subacute Ischemic Stroke Patients

Stroke, Acute Clinical Trial

Official title: Comparison Between the Effect of Unihemispheric and Bihemispheric Transcranial Direct Current Stimulation on Spasticity and Motor Outcome in Subacute Ischemic Stroke Patients: as Add on Therapy

Status Completed

Clinical Trial Summary

This is a randomized clinical trial to study the effect of tDCS in participants with subacute ischemic stroke, the study participants will be randomly assigned into three groups; bihemispheric, unihemispheric and sham group.

Clinical Trial Description

Despite the central origin of stroke affecting the primary motor cortex M1, majority of the rehabilitative techniques of physical therapy and occupational therapy practice depending peripheral methods for gaining motor functions. There is a great need to develop methods in order to improve the outcome of physical or medical rehabilitation and enhance long-term functional outcome. Many researches' work over the past several years have inspected the use of transcranial direct current stimulation (tDCS) to promote the advantageous effect of neurological rehabilitation.

The aim of This study Is to compare between the effect of unihemispheric and bihemispheric tDCS on the motor outcome, and spasticity in sub-acute ischemic stroke patients.

Thirty sub-acute ischemic stroke patients participated in the study, randomly assigned to one of three groups-tDCS bihemispheric or unihemispheric or sham group. Those patients had stroke in the last 3 months at maximum with NIH stroke score less than 25. ActivaDose tDCS (USA), the only FDA cleared device available for tDCS used in the clinical study to deliver noninvasive brain stimulation, consisted of 20 minutes of 2 mA in each session for twelve sessions three sessions per week. All participants received physiotherapy and rehabilitation therapy was tailored to meet all patients' deficits, and lasted a total of 45 minutes per day, 3 days per week for four weeks. ;

Related Conditions & MeSH terms

• Gait Disorders, Neurologic
• Hemiparesis
• Hemiplegia
• Hemiplegic Gait
• Ischemia
• Ischemic Stroke
• Motor Activity
• Muscle Spasticity
• Paresis
• Spastic
• Spasticity, Muscle
• Stroke
• Stroke, Acute
• Stroke, Ischemic
• Stroke, Lacunar

• NCT number: NCT04770363
• Study type: Interventional
• Source: Alexandria University
• Status: Completed
• Phase: N/A
• Start date: February 1, 2021
• Completion date: June 20, 2021