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Sore Throat clinical trials

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NCT ID: NCT04910659 Recruiting - Pain, Postoperative Clinical Trials

Acupuncture in Prevention of Postoperative Sore Throat Due to Classical Laryngeal Mask

Start date: January 1, 2020
Phase: N/A
Study type: Interventional

the aim of our study is to investigate if stimulation of the P6, LI4 and LI11 acupuncture points via laser acupuncture prevents sore throat caused by the classic laryngeal mask.

NCT ID: NCT04771026 Completed - Sore Throat Clinical Trials

The Effectiveness of Preemptive Nebulized Dexamethasone in Reducing Post-Operative Sore Throat in Supraglottic Airway

SGA
Start date: December 1, 2020
Phase: N/A
Study type: Interventional

This study aims to study the effectiveness of preoperatively nebulized dexamethasone in reducing the incidence and severity of Post Operative Sore Throat, POST in patients undergoing surgery under general anesthesia using the Ambu® AuraGainTM SGA device, with secondary aims of determining the effectiveness of dexamethasone in reducing post-operative cough severity and hoarseness of voice

NCT ID: NCT04715932 Completed - Pain Clinical Trials

Study of Hesperidin Therapy on COVID-19 Symptoms (HESPERIDIN)

Hesperidin
Start date: February 18, 2021
Phase: Phase 2
Study type: Interventional

The main aim of this study is to determine the effects of short-term treatment with hesperidin on COVID-19 symptoms in comparison with a placebo. Treatment effects will be observed through a symptoms diary that will be completed by participants throughout the study and by taking the oral temperature daily.

NCT ID: NCT04612829 Completed - Sore Throat Clinical Trials

To Check Effectiveness of Medistus Antivirus Lozenges for Cough

Start date: August 23, 2017
Phase: Phase 2/Phase 3
Study type: Interventional

A thraot infection sometimes called pharyngitis can be either a bacterial or a viral infection leading to inflammation of the tissues of the throat that causes redness, pain and swelling of the walls and structure of the throat. The throat or Pharynx is the tube like structure that carries both food to the oesophagus and air to your wind pipe (called the larynx). Infective agents of the throat most often enters through the month or nose. Many of these infections are viral, other can be caused by bacteria such as Streptococcus Pyogenes, or Group A streptococcus. Symtoms of throat infections most commonly includes pain and a sensation of heat in the throat or Pharynx. Viral infections accounts for approx. 70% of all pharyngitis. Rhinovirus is the most common cause of viral infections. The other common causes of viral infections in descending order are corona virus, adeno virus, para influenza, and influenza virus. Viral infections are more common during the winter month with the exception of adeno viruses which occur year round. Viral Pharyngitis is spread through similar mechanism as other viral infections. Hand to mouth contact, contact with oral secretions, and sharing common utensils, all contributes to viral spread. Prevention of the spread of diseases is based on frequent hand washing, and clinical symptoms of different viruses are more prevalent during certain seasons. Coryza, conjectivitis, malease, or fatigue, hoarseness, and low grade fever such as the presence of viral phayngitis. Subjects with viral pharyngitis can also have atypical symptoms such as mouth breathing, nausea, abdominal pain, and diarrhoea. Medistus Antivirus is a medical device product with a noble impact. Kistosyn 100 extract contains polyphenols, and with the help of gum arabic, it forms a protective film over the mouth and throat mucus membranes. This protective Barrier lead to a physical (mechanical) barrier against viruses and bacteria which prevent their penetration into body cells, and their further propagation. Due to this physical effect, resistance development is not possible.

NCT ID: NCT04334616 Completed - Sore Throat Clinical Trials

POST: Comparison of Macintosh Laryngoscope vs Video Laryngoscope in Patients Intubated by Anaesthesia Trainee

POST
Start date: June 19, 2017
Phase: N/A
Study type: Interventional

OBJECTIVES The objective of this study is to compare the frequency of POST in patients intubated by trainee anaesthetist using Video LaryngoscopeTM(VDL) versus Conventional Macintosh Laryngoscope (CL) at a tertiary care hospital in Karachi, Pakistan OPERATIONAL DEFINITIONS 1. Sore Throat: A sore throat is pain, scratchiness or irritation of the throat usually from irritation or inflammation of the throat (pharynx)(11). The visual analogue scale (0-10) will be used to evaluate the severity of sore throat 2. Trainee Anesthetist: Anesthesia residents level I and II having experience of more than six months. They will have to achieve the initial competence of doing intubation under direct supervision and need to be familiar with conventional as well as VDL technique. HYPOTHESIS: NULL HYPOTHESIS: There is no difference in the frequency of POST in patients intubated by trainee anaesthetists using VDLTM versus conventional Macintosh laryngoscope. ALTERNATE HYPOTHESIS: There is a difference in the frequency of POST in patients intubated by trainee anaesthetists using VDLTM versus conventional Macintosh laryngoscope.

NCT ID: NCT04297878 Not yet recruiting - Sore Throat Clinical Trials

The BLIS Study: a Feasibility Study Assessing Compliance, Acceptability and Colonisation With Different Dosing Regimens of the Probiotic Supplement Streptococcus Salivarius K12 (Bactoblis®) in Adults

Start date: March 5, 2020
Phase: N/A
Study type: Interventional

Short title The BLIS study Full title A feasibility study assessing compliance, acceptability and colonisation with different dosing regimens of the probiotic supplement Streptococcus salivarius K12 (Bactoblis®) in adults Population 50 human adults with or without a history of significant sore throat in the past 12 months. We primarily aim to recruit participants with a history of sore throat, however we will also recruit healthy individuals if we are struggling to meet our recruitment target. Interventions Two groups will receive two different dosing regimens of Ssk12 probiotic oral lozenges: - Group A: two SsK12 lozenges at night on days 1, 7 and 14. - Group B: one SsK12 daily at night for 14 days. Throat swabs will be taken at baseline, and days 2, 7, 14, 21, 35 Objectives 1. To evaluate the prevalence of colonisation with SsK12 (as determined by real-time Polymerase Chain Reaction [PCR] and culture of participant-take whole-mouth swabs at pre-determined time points during the study) 2. To evaluate the acceptability of the two dosing regimens (as measured by participant-completed questionnaires) 3. To evaluate participants compliance with the two dosing regimens (as reported by participants during completion of the questionnaires) Rationale SsK12 probiotic supplements are recognised as safe food ingredients, and there is preliminary evidence to support their use as prophylactic therapy to prevent episodes of pharyngo-tonsillitis. Existing clinical trials have all given SsK12 once daily over a period of months. It remains unclear whether a once-daily dosing regimen is needed in order to establish and maintain colonisation. Study design This is a prospective study for which we will recruit healthy adult participants with and without a history of sore throat/ pharyngo-tonsillitis. We will evaluate [1] the acceptability and feasibility of two different dosing regimens of SsK12 supplements (taken as oral dissolvable lozenges), and [2] compare the prevalence of colonisation with SsK12 at various time points in order to determine how long colonisation is maintained following a loading dose. A baseline whole-mouth swab will be taken, and participants will be randomly assigned (in a 1:1 ratio) to one of two groups ('A' or 'B'). Group A will take two SsK12 lozenges at night on days 1, 7 and 14. Group B will take SsK12 at night for 14 days. Participants will be provided with instruction on how to perform a self-taken whole-mouth swab, and asked to take swabs on days 2, 7, 14, 21, and 35, and return these to the study team by post. They will also be asked to complete two short online questionnaires (on day 14 and day 35) about their compliance with the probiotic, as well as their views on the dosing regimen and other aspects of the study. Maintenance of colonisation will be assessed using analysis of the returned throat swabs. No follow-up will be undertaken after day 35. Sample size Total = 50 (25 in group A, and 25 in group B) Setting 1. NIHR Clinical Research Facility, Southampton General Hospital 2. Cowley Road Medical Practice, Oxford

NCT ID: NCT04203810 Completed - Cough Clinical Trials

Effectiveness and Tolerability of Ectoin® Mouth and Throat Spray Althaea Honey (ERS09)

Start date: January 14, 2020
Phase: N/A
Study type: Interventional

The aim of this multicentre, actively controlled, randomized, open label, parallel group, prospective, comparator study is to collect data on the clinical effectiveness and tolerability of the medical device ERS09 compared to a well-established comparator spray in the symptomatic treatment of sore throat due to acute pharyngitis and dry cough.

NCT ID: NCT04184778 Completed - Sore Throat Clinical Trials

Does Tracheal Tube Size Affect Patient's Experience of Postoperative Sore Throat and Hoarseness

Start date: February 1, 2019
Phase: N/A
Study type: Interventional

How tube size affect patient's experience of postoperative sore throat and hoarseness

NCT ID: NCT04115865 Withdrawn - Sore Throat Clinical Trials

Assessment of Post-operative Sore Throat After Scheduled General Anesthesia

POST
Start date: January 2020
Phase:
Study type: Observational

Precise description of the technique for intubation or laryngeal mask placement during general anesthesia Research on factors that can influence sore throat due to the placement of an endobuccal or endotracheal device during general anesthesia

NCT ID: NCT04085744 Completed - Clinical trials for Intubation Complication

A Comparison Of Local Anesthetic Agents And Steroid On Tracheal Tube Cuff

LA-STEROID
Start date: November 1, 2019
Phase: N/A
Study type: Interventional

This study aims to compare effects of two different agents on complications due to tracheal tube cuff in pediatric patients. Sore throat, hoarseness, laryngospasm, bronchospasm are the main complications.