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Sore Throat clinical trials

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NCT ID: NCT05343429 Recruiting - Sore Throat Clinical Trials

Preoperative Aspirin and Benzydamine Hydrochloride Gargles on Severity and Duration of Post-Operative Sore Throat

Postbenas
Start date: April 1, 2022
Phase: Phase 4
Study type: Interventional

Post-operative sore throat (POST) following General Anesthesia with endotracheal is a common symptom and drains resources. The researchers will compare preoperative gargling of Asprine and Benzydamine HCL to study comparative effects on intensity and duration of POST. Data collected as such will be analyzed to reach at a conclusion.

NCT ID: NCT04910659 Recruiting - Pain, Postoperative Clinical Trials

Acupuncture in Prevention of Postoperative Sore Throat Due to Classical Laryngeal Mask

Start date: January 1, 2020
Phase: N/A
Study type: Interventional

the aim of our study is to investigate if stimulation of the P6, LI4 and LI11 acupuncture points via laser acupuncture prevents sore throat caused by the classic laryngeal mask.

NCT ID: NCT04083417 Recruiting - Tonsillitis Clinical Trials

Sore Throat in Primary Care - a Comparison of Phenoxymethylpenicillin and no Antibiotic Treatment

Start date: September 9, 2019
Phase: Phase 4
Study type: Interventional

Sore throat is the second most common cause of antibiotic prescribing in primary care in Sweden. Guidelines for sore throat focus on identifying people with sore throat where there are 3 and 4 specified criteria and where near patient tests identify group A streptococci (GAS). In these cases, phenoxymethylpenicillin is recommended. Studies that have identified microorganisms in sore throat show that there are other bacteria and viruses than GAS, that give similar symptoms and that sometimes no microorganism is trapped despite pronounced symptoms. In recent years, a bacterium F. necrophorum has been identified, which is found in increased incidence of sore throat, but it is also found in healthy individuals. In clinical practice, many patients are treated with penicillin even if GAS is not captured. This may be because the doctor perceives the patient as sick or because other bacteria are not caught with a near patient test which causes the doctor to treat anyway. The specific aims are to in patients with GAS-negative sore throat and 3 and 4 criteria, aged 15 years and older in primary care, study whether phenoxymethylpenicillin treatment shortens the duration of the disease, reduces the symptom intensity and sickness absence, and investigates the importance of other microorganisms than GAS in sore throat. The study is a randomized controlled trial in which patients with sore throat are randomized to phenoxymethylpenicillin 3 times daily for 10 days or to no antibiotic therapy. There will also be and a reference group with severe (Centor score 3-4), GAS-positive acute tonsillitis. Blood samples for inflammatory and immunological response to infections are taken. Throat samples for culture of F. necrophorum and streptococcal groups C and G, as well as polymerase chain reaction (PCR) analysis for bacteria and viruses are also taken at inclusion and at follow-up. The outcome will be followed in a patient diary for 10 days and at a return visit after 18-24 days where the clinical outcome is asked for and where the blood- and throat samples are repeated. Follow-up will also takes place via e-mail after 1 and 3 months.

NCT ID: NCT03915561 Recruiting - Clinical trials for Postoperative Complications

Effect of Intravenous Dynastat on Postoperative Sore Throat

Start date: March 1, 2019
Phase: Phase 2
Study type: Interventional

A postoperative sore throat (POST) after tracheal intubation is one of the most common postoperative problems causing dissatisfaction to participants, including sore throat, dry throat, cough, sputum, hoarseness and even dysphagia. Both nonpharmacological and pharmacological measures have been attempted to alleviate the incidence and severity of POST with variable success. Airway inflammation may be important in the pathogenesis of these symptoms in intubated participants but however, there was still no study to investigate the effect of cyclooxygenase-2 (COX-2) for the prevention of POST. So, the investigators' study will be the first one to investigate if perioperatively intravenous (IV) Dynastat injection can be used as a new indication for POST prevention.

NCT ID: NCT03846713 Recruiting - Clinical trials for Intubation Complication

Thermosoftening of Double-lumen Tube for Airway Exchanger Catheter

Start date: December 27, 2017
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate the effect of double-lumen tube thermal-softening before intubation on the success rate of tube exchange by airway exchange catheter.

NCT ID: NCT03391700 Recruiting - Sore Throat Clinical Trials

Effect of Intraoperative Muscle Relaxation Depth on Postoperative Sore Throat and Hoarseness After General Anesthesia

Start date: August 1, 2017
Phase: N/A
Study type: Interventional

Investigators assess and compare postoperative sore throat and hoarseness in the group maintaining moderate relaxation and deep relaxation during operation.

NCT ID: NCT03369132 Recruiting - Sore Throat Clinical Trials

Efficacy of Natural Seawater Based Throat Spray in Acute Sore Throat Relief

FLASH
Start date: November 6, 2017
Phase: N/A
Study type: Interventional

Prospective, randomized, double-blind, placebo-controlled, multicentre clinical trial to assess the efficacy and tolerability of natural seawater based throat spray among adult patients with acute sore throat.

NCT ID: NCT01838993 Recruiting - Sore Throat Clinical Trials

Inhalation of Lidocaine Before Intubation

Start date: January 2013
Phase: N/A
Study type: Interventional

We investigate the potential benefits of ultrasound-driven lidocaine inhalation immediately before induction.