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Social Behavior clinical trials

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NCT ID: NCT05379959 Completed - Motivation Clinical Trials

Effects of Stimulants on Behavioral and Neural Markers of Social Motivation, Ability, and Neural Markers of Social Function

MASM
Start date: May 11, 2022
Phase: Early Phase 1
Study type: Interventional

To study the effects of MDMA, compared to a prototypical stimulant, on social motivation, social ability, and neural indices of social function in healthy volunteers

NCT ID: NCT05345054 Completed - Colorectal Cancer Clinical Trials

The Deep South Surgical Equity Research Network: Addressing Socioecological Determinants of Health

Start date: August 1, 2022
Phase:
Study type: Observational

Rationale: Older African Americans undergoing surgery are a vulnerable and growing population at high risk for poor surgical outcomes and disparities. Few programs have focused on this population due to a fragmented understanding of the needs of this population. Objectives: While socioecological determinants of health (SEDOH) such as health literacy and socioeconomic status are known drivers of surgical disparities, an estimated 36-47% of surgical disparities remains unexplained. This gap results from limitations of current clinical datasets in capturing SEDOHs. This pilot study aims to fill this gap by (i) collecting granular SEDOH data, (ii) identifying barriers to surgical care for older African Americans, and (iii) establishing a multi-institutional clinical database through a socioecological context. These findings will help understand how SEDOHs drive surgical disparities and inform development of interventions to eliminate them in elderly African Americans. Design and Methods: Guided by the socioecological model of health, the investigators will use mixed-methods to achieve the objectives. First, the investigators will assess the acceptability and feasibility of a 58-item SEDOH survey based on the NIH PhenX toolkit. After distributing this survey to 36 elderly (≥65 years) African American patients undergoing surgery at 3 rural, UAB-affiliated hospitals (Alex-City, Greenville, Demopolis) the investigators will conduct detailed theory guided assessments of acceptability and feasibility (SA1). Second, the investigators will conduct key informant interviews of individuals from all 5 socioecological levels at each rural hospital (n=10) to identify additional barriers and facilitators to surgical care. The investigators will purposively sample 100% of participants at the patient and caregiver level (n=12) to be elderly African Americans (SA2). Finally, the investigators will link measured SEDOH data with standardized clinical data at each hospital to establish a novel database (SA3). These findings will establish a process to measure SEDOHs across the Deep South and set the foundation for a unique database to study surgical disparities. Significance: Development of effective multilevel interventions to eliminate surgical disparities in older African Americans is dependent on a clearer understanding of the contextual drivers of these disparities. This pilot study will accelerate understanding of these mechanism(s) through SEDOHs. It will establish a process to measure SEDOHs, identify additional barriers to surgical care not captured by NIH instruments, and build the database to study these relationships. Such findings will have the potential to impact vulnerable surgical populations in the Deep South and support the Deep South RCMAR mission to promote health and optimize health outcomes for older and rural African Americans.

NCT ID: NCT05260515 Not yet recruiting - Clinical trials for Mild Cognitive Impairment

Protecting Alzheimer Caregivers Using Technology Through Staying Sharp

PROACTS
Start date: April 30, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

PROACTS is a Phase I/II study to assess the efficacy of AARP Staying Sharp online health program, focusing on the health of non-professional home-based caregivers of persons with Alzheimer's disease and related dementias (ADRD). PROACTS has three aims. Aim 1&2 is an one-time survey study to evaluate the current uptake and utilization of Staying Sharp among caregivers. Aim 3 is a single-group intervention to assess how Staying Sharp may maintain health and function for caregivers of persons with ADRD. Participants will participate in a 4-month program with a 4-month follow-up. Aim 1&2: Characterize caregivers of persons with ADRD using Staying Sharp and evaluate user experiences of Staying Sharp. Aim 3: Establish preliminary efficacy of Staying Sharp program.

NCT ID: NCT05124665 Completed - Hiv Clinical Trials

Interrupting HIV and TB Stigma in the Household in Uganda

Start date: October 25, 2021
Phase: N/A
Study type: Interventional

The investigators will carry out a prospective, household cluster-randomized, implementation trial evaluating a complex, multi-component, social and behavioral intervention designed to normalize the acceptance of HIV testing in the household and increase diagnosis of HIV.

NCT ID: NCT04656990 Active, not recruiting - Sedentary Behavior Clinical Trials

SKIPping With PAX: An Integrated Gross Motor and Social-Emotional Skill Intervention

Start date: September 1, 2020
Phase: N/A
Study type: Interventional

The purpose of this study was to test the effects of an integrated intervention on the gross motor and social-emotional development of rural preschool boys and girls. A secondary purpose was to examine intervention effects on physical activity and sedentary behavior. An exploratory aim was to examine the role of executive functioning skills on intervention outcomes. This study featured a repeated measures (baseline, six-month posttest, three month retention [nine-month follow-up]), control group, experimental design. Classrooms were randomly assigned to either the experimental or control groups. Experimental participants received intervention while control participants received business as usual curricula.

NCT ID: NCT04451876 Completed - Hypertension Clinical Trials

Social Media Use ,Online Health Information Seeking and Knowledge on Hypertension

Start date: August 17, 2020
Phase:
Study type: Observational

The percentage of hypertension among adults aged 18 is relatively high which is about 30% in Malaysia. Uncontrolled hypertension will increase the risk of diseases especially cardiovascular disease. However, adults still lack awareness about the importance of knowledge of hypertension. In between, online health information seeking and the use of social media to gather health information have been quite a norm among students. The wide use of this platform has been proven in various researches and studies. This study will be conducted among the undergraduate students in FMHS, UPM to look at the various socio-demographic factors associated with their level of knowledge on hypertension. Therefore, this may lead to a need to plan awareness programs on hypertension and to increase the knowledge of hypertension among health science students in the future. A cross-sectional study design will be done for this study. All undergraduate students in FMHS, UPM will be selected through simple random sampling. Online questionnaires will be given via the selected student email platform. However, there are limitations for this study where we only focus on the students of FMHS, UPM. Hence, the results of this study may be limited to them only. The causal relationship cannot be determined by this study design as well. The purpose of this study is to determine the social media use, online health information seeking practices with knowledge on hypertension among undergraduate students in FMHS, UPM, and its associated factors

NCT ID: NCT04417751 Completed - Dementia Clinical Trials

Care at 360º: A Long-term Individual Cognitive Stimulation Program

Start date: July 1, 2020
Phase: N/A
Study type: Interventional

The aim of the intervention proposed in the present study is to assess the effect of a cognitive stimulation (CS) intervention program in an individual and long-term format, for non-institutionalized elderly people with neurocognitive disorders and in a situation of social vulnerability. Specifically, to test the effectiveness of CS on the global cognitive state, on mood state, on quality of life and on functional state. The program will be composed by 50 sessions, including three of assessment sessions (pre, intra and post-intervention). Each session will have a duration of 45 minutes with a weekly frequency. Control group participants will maintain their treatment as usual.

NCT ID: NCT04396470 Withdrawn - Clinical trials for Prader-Willi Syndrome

tVNS in Children With Prader-Willi Syndrome

Start date: July 2020
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of the current project is to test the impact of transcutaneous vagus nerve stimulation (tVNS) on social ability in children with Prader-Willi Syndrome (PWS). Social ability and blood neuropeptides associated with social functioning will be measured before and after engagement in 12 weeks of tVNS therapy.

NCT ID: NCT04328350 Recruiting - Childhood Cancer Clinical Trials

Social Experiences of Adolescents and Young Adults With Cancer

Start date: October 12, 2020
Phase:
Study type: Observational

Participants are being asked to take part in this clinical trial, a type of research study, because investigators want to learn more about the social experiences adolescents and young adults who are being treated or have been treated for cancer. Primary Objectives - Describe differences in social experience variables (peer connectedness, perceived social competence, parent versus peer attachment) based on treatment status: on versus off therapy. - In on-therapy patients, describe differences in social experience variables (peer connectedness, perceived social competence, parent versus peer attachment) based on developmental stage: high school versus post-high school. Secondary Objectives - Assess the social support and peer interaction needs of AYA with cancer as a means of determining stakeholder interest and need for psychosocial interventions targeting social experiences. - Using qualitative interviews, explore patient perceptions of the impact of cancer on social experiences among AYA, particularly with regards to changes in friendships as a result of the cancer diagnosis and the role of the hospital in helping or hindering friendship maintenance/development. Exploratory Objectives - Explore differences in social experience by demographic, disease and treatment factors, including: gender, diagnostic category (brain tumor, leukemia/lymphoma, solid tumor), late effects/symptom burden, and treatment (e.g., treatment intensity, serious medical events). - Explore associations between perceived impact of cancer and social experience in AYA. - Explore associations between use of social media and social experience. - Explore associations between social experiences and overall functioning (quality of life, distress, coping). - Explore the possibility of subclasses of AYA by using person-centered analyses to empirically derive profiles of social experience.

NCT ID: NCT04310475 Completed - Psychosis Clinical Trials

Virtual Reality Assisted CBT for Social Difficulties: a Feasibility Study in Early Intervention for Psychosis Services

Start date: August 23, 2019
Phase: N/A
Study type: Interventional

People experiencing psychosis might find social interactions stressful and avoid them. This can result in isolation and can affect relationships, employment and quality of life. Improving social functioning is a really important aspect of recovery. Facing social situations after the first episode of psychosis can be very difficult and provoke intense anxiety. However, research has shown that the earlier intervention is offered, the better the outcome. Therefore, improving therapies for people experiencing their first episode of psychosis is a key target for research. Virtual Reality presents a unique opportunity to bring real-life-type environments into a therapy session to help people to overcome their distress in social situations and make them feel less anxious. Virtual Reality assisted Therapy (VRT) provides a 'safe space' to practice strategies and techniques to help people work towards improving their social functioning, build new ways of coping with stress and assist them in their recovery. The study uses a standard CBT model and integrates a Virtual Reality environment into it to support exposure and behavioural experiments for social difficulties, which are a key component of treatment.