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Smoking, Tobacco clinical trials

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NCT ID: NCT03951766 Completed - Smoking Cessation Clinical Trials

Version 2 of the Smoking Cessation Smartphone App "Smiling Instead of Smoking" (SiS)

Start date: June 24, 2019
Phase: N/A
Study type: Interventional

The overall goal of this pilot study is to solicit feedback from nondaily smokers looking for smoking cessation support online (n=90) about Version 2 of a smartphone app investigators designed to support smoking cessation, and to test if within-person theorized mechanisms of change are occurring as participants undergo the app-assisted quit attempt. Data sources will be passively collected smartphone app usage data, surveys and, in a sub-sample (n=20), online video-conference user feedback sessions. Results will be used to guide the design of Version 3.0 of the "Smiling Instead of Smoking" (SiS) smartphone app. Specifically, the aims of this study are to: 1. Assess ease-of-use and helpfulness of the app, as rated by app users 6 weeks after their chosen smoking cessation date 2. Test if within-person changes occur in theorized mechanisms of behavior change as nondaily smokers undergo a SiS app assisted quit attempt 3. Identify app features in need of improvement, as identified by passively recorded app usage patterns, REDCap open-ended survey items, and, in a sub-sample, user feedback sessions (n=20)

NCT ID: NCT03950427 Recruiting - Smoking Cessation Clinical Trials

PARQuit Smoking Cessation Intervention for Adults With Serious Mental Illness

PARQuit
Start date: July 8, 2019
Phase: Phase 4
Study type: Interventional

This is a research study about a smoking cessation program tailored for adults with serious mental illness (SMI). The program uses a Videogame-based Physical (VIP) activity, smoking cessation counseling, and medication (bupropion),

NCT ID: NCT03920319 Completed - Smoking Clinical Trials

Bupropion and Cigarette-Related Cues in Smokers

Start date: January 1, 2004
Phase: Phase 1
Study type: Interventional

Randomized, double-blind, before-after controlled trial to assess changes in regional brain activation in response to cigarette-related cues from before to after treatment with bupropion (vs placebo).

NCT ID: NCT03918031 Completed - Depression Clinical Trials

Personalized Feedback for Distress Intolerant Smokers

Start date: July 15, 2019
Phase: N/A
Study type: Interventional

This project will develop and refine a computer-delivered integrated Personalized Feedback Intervention (PFI) that directly addresses smoking and distress tolerance. The PFI will focus on feedback about smoking behavior, distress tolerance, and adaptive coping strategies.

NCT ID: NCT03891602 Withdrawn - Lung Cancer Clinical Trials

DECIDE: Developing Tools for Lung Cancer Screening Discussion Improvement

DECIDE
Start date: March 22, 2019
Phase:
Study type: Observational

The purpose of this study is to learn about discussion between clinicians and their patients related to lung screening. Survey answers will be collected from both clinicians and their patients.

NCT ID: NCT03879889 Completed - Smoking, Tobacco Clinical Trials

Smoking Reduction Intervention for Smoking Parents of Paediatric Patients in Hong Kong

Start date: February 1, 2017
Phase: Phase 4
Study type: Interventional

A randomized controlled trial to evaluate the effectiveness of smoking reduction interventions for smoking parents in paediatric hospital setting in Hong Kong.

NCT ID: NCT03870022 Completed - Smoking Cessation Clinical Trials

Pivot Breath Sensor Performance Study

Start date: March 1, 2019
Phase: N/A
Study type: Interventional

A clinical study enrolling 70 subjects to: - evaluate the user performance of the Pivot Breath Sensor - compare measurements from the Pivot Breath Sensor to a similar device - assess user documentation comprehension - obtain feedback on the Pivot Breath Sensor via rating scales. No medical decisions will be made related to test results.

NCT ID: NCT03857139 Withdrawn - Smoking Cessation Clinical Trials

Opioids and Smoking Cessation

Start date: December 2020
Phase: Phase 4
Study type: Interventional

The selection hypothesis of smoking prevalence posits that smokers who are not able to quit successfully are "burdened" by specific characteristics that make it more challenging to quit1. For example, those less successful in quitting smoking may be more nicotine dependent or more likely to suffer from substance use, psychiatric, or medical conditions. In line with this perspective, smoking prevalence has stabilized in the US, presumably because the remaining population has become increasingly representative of those "at-risk smokers" who are unable to quit2. Emerging evidence suggests that persons who suffer from opioid misuse, defined as opioid use without a prescription, at a dose or frequency higher than prescribed, or for a non-medical purpose (e.g., getting high),3 may constitute such a high-risk group. Opioid misuse affects greater than 16% adults who use opioids4 and up to 29% of those with chronic pain.5 The prevalence of tobacco smoking in this group may exceed twice that observed in the general population, and smokers misusing opioids are almost twice as likely to be dependent on nicotine6,7. Yet, the role of opioid misuse in periods of early abstinence and smoking cessation has yet to be explored. The main objective of the present proposal is to fill existing gaps in knowledge by examining the extent to which opioid misuse is associated with decreased success during early smoking abstinence and over the course of an attempt to quit smoking, and to identify mediators and moderators of opioid-smoking relations in this context. This contribution is clinically-significant from a public health standpoint because it will directly guide the development of novel psychosocial/behavioral smoking cessation interventions to help this high-risk population of smokers quit by targeting unique vulnerability processes that result in poor cessation outcomes.

NCT ID: NCT03835260 Completed - Smoking Cessation Clinical Trials

Pivot Breath Sensor Human Factors and Usability Study

Start date: February 4, 2019
Phase: N/A
Study type: Interventional

Prospective, observational open label, single center study enrolling up to 15 subjects to evaluate human factors and usability of the Pivot Breath Sensor.

NCT ID: NCT03742154 Completed - Smoking Cessation Clinical Trials

Hollings Cancer Center Varenicline Sampling Study

Start date: December 3, 2018
Phase: Early Phase 1
Study type: Interventional

The purpose of this study is to learn what happens when people are given a free, 4-week, sample of varenicline, a smoking cessation medication. Investigators will look at quit attempts, changes in smoking, and attitude towards varenicline, in both smokers who want to quit and those who do not. Smoking use causes a number of deaths and diseases, including heart disease and cancer. All smokers are advised to quit. Varenicline (sometimes called Chantix), is a prescription medication approved by the US FDA. Many studies show that use of varenicline can help smokers quit smoking. Varenicline is a prescription medication, which usually means that people have to see a doctor to get it. This study examines a different way to deliver varenicline, delivered directly to participants for a few weeks, and without need to see a doctor. This method is called "varenicline sampling." The study is sponsored by the Hollings Cancer Center at the Medical University of South Carolina. The study is being done at the Medical University of South Carolina, but study recruitment is based state-wide, throughout South Carolina.