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Scoliosis clinical trials

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NCT ID: NCT04868331 Completed - Clinical trials for Adolescent Idiopathic Scoliosis

Cardiovascular Responses in Adolescent Idiopathic Scoliosis Girls

Start date: May 18, 2021
Phase: N/A
Study type: Interventional

The aims of this pilot study are to determine the metabolic demand and exercise intensity level of E-Fit exercise intervention by evaluating the cardiovascular responses in AIS girls and whether the cardiovascular responses for AIS girls performing E-Fit will behave in the same way as compared to healthy controls. We hypothesise that 1) the metabolic demand and exercise intensity of E-Fit exercise intervention is equivalent to moderate-to-vigorous level; and 2) AIS girls have different cardiovascular responses as compared to healthy controls

NCT ID: NCT04846296 Completed - Quality of Life Clinical Trials

The Turkish Adaptation, Validity and Reliability Study of the Quality of Life Profile for Spinal Deformities

Start date: April 15, 2021
Phase:
Study type: Observational [Patient Registry]

The purpose of this study is to translate and culturally adapt the quality of life profile for spinal deformities (QLPSD) to Turkish language and test the validity and reliability of Turkish version of QLPSD in patients with adolescent idiopathic scoliosis.

NCT ID: NCT04833868 Completed - Clinical trials for Scoliosis Idiopathic

Effect of Hippotherapy and Schroth Exercise on Pulmonary Function and Aerobic Capacity in Idiopathic Scoliosis

Start date: February 20, 2020
Phase: N/A
Study type: Interventional

BACKGROUND: Idiopathic scoliosis has been identified as a common spinal malalignment that negatively impacts the respiratory system and physical conditioning in adolescents. Hippotherapy is an equestrian intervention that optimizes physical performance and mobility in a bunch of contexts; however, its influence on pulmonary function remains unclear. AIM: This research aimed to analyze the impact of ten weeks of hippotherapy combined with Schroth exercises on ventilatory function and aerobic capacity in AIS. DESIGN: Randomized Controlled Trial SETTING: Outpatients attend a single center that includes a rehabilitation room and recreational riding center. POPULATION: Forty-five patients were arbitrarily recruited to the experimental (N= 22) and control group (N=23). METHODS: Patients in the experimental group received 30 minutes of walking and sitting trot training, 15 sessions split into 2 phases over ten weeks. The two groups attended a 60-minute session of Schroth's intervention, 3 times/ week for 10 weeks. Two-way ANOVA for between-group comparisons and independent t-test for within-group comparisons were used in the statistical analysis.

NCT ID: NCT04822935 Completed - Clinical trials for Scoliosis; Adolescence

Postoperative Pain in Adolescent Idiopathic Scoliosis Surgery

Start date: June 30, 2021
Phase: N/A
Study type: Interventional

Scoliosis is a 3-dimensional, structural deformity of the spine. Idiopathic scoliosis is the most common type and it constitutes 75-80% of all scoliosis. Surgical methods are the most effective way to correct the deformity in patients who cannot achieve adequate improvement with supportive therapy. Adolescent idiopathic scoliosis surgeries are among the most invasive surgeries performed on children and adolescents. Large surgical incision and massive tissue damage cause severe postoperative pain. In this study, we aim to compare posterior instrumentation (PE) and vertebral body tethering (VBT) surgeries performed in adolescent idiopathic scoliosis patients in terms of anesthetic management and postoperative pain.

NCT ID: NCT04791059 Completed - Dexmedetomidine Clinical Trials

Low-dose S-ketamine and Dexmedetomidine in Combination With Opioids for Postoperative Analgesia

Start date: April 9, 2021
Phase: Phase 4
Study type: Interventional

Scoliosis correction surgery is followed with severe pain. Patients after scoliosis correction surgery usually require high dose opioids and long duration analgesia, which may increase side effects and even drug tolerance. S-ketamine is the pure dextrorotatory enantiomer of ketamine with stronger analgesic effect and less side effects, but mental side effects is a major concern. Dexmedetomidine can be used as an analgesic supplement; it also improves sleep quality in postoperative patients. We hypothesize that low-dose ketamine and dexmedetomidine in combination with opioids may have synergistic effect in analgesia and reduce drug-related side effects. This study aims to explore the effect of low-dose of S-ketamine and dexmedetomidine in combination with opioids for postoperative patient-controlled intravenous analgesia in patients following scoliosis correction surgery.

NCT ID: NCT04773509 Completed - Scoliosis Clinical Trials

Effect of Intraoperative Paravertebral Block on Postoperative Pain and Recovery in Patients Undergoing Mechanical Correction for Scoliosis

Start date: June 24, 2021
Phase: N/A
Study type: Interventional

Pain management after scoliosis surgery is challenging for the anesthesiologists. This surgery causes severe postoperative pain and patients undergoing these operations are children or adolescents who are increased pain sensation compared with adults. Therefore, we aim to evaluate whether intraoperative paravertebral block (PVB) decreases postoperative pain in these patients. Thirty-two patients scheduled for mechanical correction due to scoliosis will be divided into PVB (n=16) and control (n=16) groups. Randomly selected patients of the PVB group are performed PVB with 0.2% ropivacaine on both sides. In contrast, PVB are not performed in the control group.

NCT ID: NCT04720677 Completed - Clinical trials for Adolescent Idiopathic Scoliosis

Psychometric Properties of Adapted Turkish Version of ISYQOL Questionnaire in Patients With AIS

Start date: January 6, 2019
Phase:
Study type: Observational

The ISYQOL questionnaire was translated into Turkish and was assessed the psychometric properties of the Turkish version of the ISYQOL in terms of test-retest reliability, internal consistency, and construct validity in this research.

NCT ID: NCT04714632 Completed - Clinical trials for Idiopathic Scoliosis

Function of Inner Ear Such as Balance and Perception of Verticality in Children With Idiopathic Scoliosis

Start date: November 1, 2018
Phase:
Study type: Observational

The purpose of this study was to evaluate vestibular function in children with idiopathic scoliosis as a possible cause of etiopathogenesis of its diagnose.

NCT ID: NCT04713397 Completed - Scoliosis Clinical Trials

Leg Length Discrepancy and Adolescent Idiopathic Scoliosis: Clinical and Radiological Characteristics

Start date: January 6, 2019
Phase:
Study type: Observational

The aim of this retrospective study is to present clinical and radiological features and their relationships for differentiating functional scoliosis due to LLD and LLD concurrent with AIS.

NCT ID: NCT04689880 Completed - Clinical trials for Degenerative Disc Disease

XLIF Decade Plate System Study

Start date: April 12, 2021
Phase:
Study type: Observational

The primary objective of this study is to evaluate the safety and performance of the NuVasive XLIF Decade Plate System as measured by patient-reported outcomes (PROs), radiographic outcomes, and reported complications.