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Scoliosis clinical trials

View clinical trials related to Scoliosis.

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NCT ID: NCT05127902 Completed - Clinical trials for Adolescent Idiopathic Scoliosis

Association Between Postural Balance and Muscle Activity of the Lumbar and Lower Limb Muscles in Female With or Without Adolescent Idiopathic Scoliosis (AIS) During Standing Balance Tasks With Upper Limb Movement

Start date: October 15, 2021
Phase:
Study type: Observational

Adolescent idiopathic scoliosis (AIS) is the most common type of three-dimensional deformity of the spine in adolescence with a clear female predominance at a prevalence rate of 3.5% in Hong Kong. AIS increases the risk of spinal degeneration, back pain, and cardiorespiratory dysfunction. These impairments caused by AIS can be related to the abnormal lateral deviation, axial rotation, and reduction of sagittal curves of the spine. AIS has been associated with asymmetrical muscle activity and impaired postural balance performance. AIS who had convex side of the major curves to the right demonstrated an increase in right side thoracic and lumbar erector spinae muscle activity during pelvic anterior, posterior, and left tilting on an unstable sitting board as measured by electromyography (EMG). Postural balance is defined as the act of maintaining, achieving and restoring a state of balance during any posture or activity. The ability of maintaining postural balance in AIS is influenced by multiple factors including spinal deformities, asymmetrical muscle activities, alteration in sensory input, central integration or motor response. Previous studies have investigated the motor response in young adults. They were found to depend more on ankle strategy than hip strategy during a balance perturbation on a movable platform. Increased lateral gastrocnemius muscle activity was also observed when centre of gravity falls forward during an EMG measurement in quiet stance. In a study of low back pain patients, training regime involving single rapid arm movement in flexion and extension was found to promote the activation of the transversus abdominis muscle and improved the feedforward postural adjustment. There are limited studies to investigate the association between somatosensory input and motor response particularly lower limb muscle activity and upper limb movement on balance control in AIS. Recent evidence also suggested that AIS tend to overestimate the severity of their spinal deformity but their perception of their body schema and spinal curvature can be improved by enhancing motor skills. Therefore, training of postural balance that involved enhancing motor skills and stimulating somatosensory system will have the potential to improve motor response as well as improve self-perceived body schema in AIS.

NCT ID: NCT05095129 Completed - Clinical trials for Idiopathic Scoliosis

The Role of Genetic Factors in the Development of Idiopathic Scoliosis in the Kazakh Population

Start date: March 23, 2022
Phase:
Study type: Observational

The purpose of this study is to identify genetic determinants of susceptibility to idiopathic scoliosis . It will assist in predicting individual risks of disease progression and would help to clarify pathophysiologic mechanisms of idiopathic scoliosis

NCT ID: NCT05059561 Completed - Clinical trials for Idiopathic Scoliosis

Temperament and Character Traits in Young Men With Idiopathic Scoliosis

Start date: July 1, 2017
Phase:
Study type: Observational [Patient Registry]

This study was designed to investigate whether the temperament and character traits of young men with idiopathic scoliosis differ from healthy individuals of the same age group and characteristics.

NCT ID: NCT05056363 Completed - Clinical trials for Adolescent Idiopathic Scoliosis

The Effects of Core Stability Training in Children With Adolescent Idiopathic Scoliosis

Start date: October 5, 2021
Phase: N/A
Study type: Interventional

Adolescent idiopathic scoliosis (AIS) is a three-dimensional structural deformity of the spine in which lateral flexion and axial rotation are seen in vertebrae with a Cobb (method for measuring spinal curvature) angle of 10° and above. AIS is the most common type of scoliosis and it occurs in the period from the onset of puberty (up to 10 years) until the closure of growth plates. Children with AIS have cosmetic effects, decrease in functional capacity, muscle weakness in certain parts of the body, decrease in quality of life and posture disorders. Lack of core stability might be causing these problems. Core stability training may have a positive effect for these problems experienced by children with AIS. Pathologies that cause the disease may originate from the nervous system and musculoskeletal system. In this study, the investigators will evaluate these systems objectively with EMG biofeedback and Isokinetic Testing. The aim of this study is to show the effect of core stability training on various problems (as we mentioned before) caused by the disease. In addition, the investigators of this study hope to contribute to the literature(with objective evaluations) about the pathological background and treatment of this challenging disease which the cause is unknown.

NCT ID: NCT05033171 Completed - Clinical trials for Scoliosis Idiopathic

Rod Shape Changing After Scoliosis Correction Surgery

Start date: September 1, 2019
Phase: N/A
Study type: Interventional

The change of the fixation-rod after posterior srew-rod fixation segmentdesis is not widely known. The recent development of the 3D scanning technics and the opportunities of the EOS 2D/3D system made us possible to have the exact rod shape immediately after implantation, and at each control examination. These progressions made us available to follow up the shape changing of the fixation-rod, hereby the changing of the correction.

NCT ID: NCT04959591 Completed - Clinical trials for Scoliosis; Adolescence

Use of Intravenous Acetaminophen in Pediatrics Undergoing Spinal Fusion Surgery

Start date: June 1, 2021
Phase: Phase 3
Study type: Interventional

The purpose of this study is to investigate whether perioperative intravenous acetaminophen administration reduces postoperative pain and opioid consumption in adolescents and pediatric patients undergoing spinal fusion surgery.

NCT ID: NCT04952285 Completed - Tranexamic Acid Clinical Trials

The Efficacy and Safety of the Loading Dose of Tranexamic Acid in Scoliosis Surgery During Perioperative

Start date: January 1, 2015
Phase:
Study type: Observational

This study intends to make full use of the advantage of spinal orthopedic surgery in our medical center.Analyze the blood loss and blood coagulation function and the influence of safety of load dose tranexamic acid (TXA) in scoliosis surgery during perioperative.

NCT ID: NCT04931433 Completed - Analgesia Clinical Trials

Intravenous Lignocaine as an Analgesic Adjunct in Adolescent Idiopathic Scoliosis Surgery

IGNITE-AIS
Start date: December 24, 2020
Phase: Phase 4
Study type: Interventional

This is a single-center study comparing the effect of intravenous (IV) Lignocaine given throughout posterior spinal fusion surgery on the reduction of morphine usage during postoperative period in adolescent idiopathic scoliosis (AIS) patients.

NCT ID: NCT04921813 Completed - Clinical trials for Adolescent Idiopathic Scoliosis

Investigation of Conservative Treatment on Adolescent Idiopathic Scoliosis Patients.

Start date: August 15, 2014
Phase: N/A
Study type: Interventional

Aim: It was aimed to investigate the effectiveness of three-dimensional scoliosis exercises and balance-coordination exercises in patients with adolescent idiopathic scoliosis.

NCT ID: NCT04885023 Completed - Clinical trials for Idiopathic Scoliosis

Efficacy Hippotherapy on Postural Asymmetries and Balance in Adolescents With Idiopathic Scoliosis

Start date: February 20, 2020
Phase: N/A
Study type: Interventional

This study showed that the addition of hippotherapy to Schroth exercises is more effective in improving postural asymmetry and balance ability in adolescents with idiopathic scoliosis compared to Schroth exercises alone. Therefore, this combination should be considered during designing a rehabilitation program for AIS