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Scoliosis clinical trials

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NCT ID: NCT04539522 Recruiting - Clinical trials for Idiopathic Scoliosis

Efficacy of a Three-dimensionally Corrective Exercise Therapy for Scoliosis

Start date: October 30, 2020
Phase: N/A
Study type: Interventional

Idiopathic scoliosis (AIS) is one of the most prevalent spinal deformity that may progress sharply during growth. It is recommended that the physiotherapeutic scoliosis-specific exercises should be the first step to treat idiopathic scoliosis to prevent/limit progression of the deformity. Three-dimensionally corrective exercise for scoliosis is based the theory of physiotherapeutic scoliosis specific exercises, which focuses on 3-dimension self-correction and consists of two parts:1)outpatient treatment including stretching, three-dimensional self-correction, balance and stability training, combined with manual fascia relaxation therapy, and and breathing training; 2)family rehabilitation: combines self-correcting gymnastics with daily posture management, etc., forming the individual exercise approach for each patient. Nevertheless, the evidence concerning three-dimensionally corrective exercise for scoliosis is inadequate. Therefore, the objective of this study is to determine the effect of three-dimensionally corrective exercise intervention on the change of Cobb angle, trunk rotation, sagittal profile, lung function, exercise endurance and health related quality-of-life, compared to conventional exercise therapy for patients with mild and moderate AIS. Informed consent will be obtained from each patient and one of their parents prior to inclusion. Eligible subjects will be divided into two groups(experimental group or control group) according to their wishes. Subjects in experimental group will perform three-dimensionally corrective exercise for scoliosis (moderate patients combined with a brace) and those in the control group will receive conventional exercise therapy (moderate patients combined with a brace). Blinded assessments at baseline and immediately post 12-month intervention will include radiographic measurement, trunk rotation, sagittal profile, lung function, exercise endurance and health related quality-of-life.

NCT ID: NCT04538092 Terminated - Clinical trials for Scoliosis Idiopathic

Complex Spine Enhanced Recovery After Surgery (ERAS)

Start date: September 14, 2020
Phase: N/A
Study type: Interventional

In the field of Adult Spinal Deformity (ASD), there are currently no standardized protocols for preoperative, intraoperative or post-operative care. New standards are being created for minimally invasive spine surgery within orthopedics and some neurosurgical centers. This study will evaluate the efficacy of an Enhanced Recovery After Surgery protocol for complex spine surgery performed for the treatment of ASD.

NCT ID: NCT04509310 Recruiting - Scoliosis Clinical Trials

Active Bodysuits for Adult Degenerative Scoliosis

Start date: January 6, 2019
Phase: N/A
Study type: Interventional

Adult degenerative (de novo) scoliosis (ADS) is a condition of the ageing population caused by degenerative changes without pre-existing spinal deformity. Pain is the most frequent problem, especially low back pain and radicular pain, and seriously affects the daily activities and health of ADS patients. The current treatment for ADS is not well defined. The main intervention for ADS treatment is surgical, but surgery is clearly not appropriate for every patient. Active bodysuits will be designed based on body alignment and pain management using special design components and incorporating active posture training from a biofeedback system. Back pain is often localized along the convexity of the curve, and passive support to the areas of pain, most likely in the lower trunk, hip and lower extremities, should be provided.

NCT ID: NCT04505579 Recruiting - Clinical trials for Scoliosis Idiopathic

The Tetherâ„¢ - Vertebral Body Tethering System Post Approval Study

Start date: October 29, 2020
Phase:
Study type: Observational [Patient Registry]

This study is an opportunity to provide continued reasonable assurance of the safety and probable benefit of The Tether HUD. The study will collect long term safety and efficacy information from patients who have had their idiopathic scoliosis treated via anterior vertebral body tethering (AVBT) with The Tether.

NCT ID: NCT04500613 Enrolling by invitation - Pain, Postoperative Clinical Trials

Erector Spinae Plane Blocks for Adolescent Idiopathic Scoliosis

Start date: February 22, 2021
Phase: N/A
Study type: Interventional

Pediatric spinal fusion (PSF) surgery is a painful procedure that can treat adolescent idiopathic scoliosis (AIS). One technique that can potentially reduce patients' pain levels and need for opioid medication is the ultrasound-guided Erector Spinae Plane Block (ESPB). The ESP block is a technique that involves injecting an anesthetic medication into the muscles of the lower back on both sides of the spine. Previous studies have shown that ESPB application led to a reduction in opioid use, and there is one pediatric case report of ESPB use in two patients undergoing PSF. However, there is still lack of evidence that the ESPB technique is feasible and effective in the pediatric patient population. The present study is designed to be the first randomized controlled trial to evaluate the role of ESPB in pediatric spinal fusion surgery and the role of ESPB within an enhanced recovery pathway.

NCT ID: NCT04500041 Recruiting - Clinical trials for Scoliosis Idiopathic

Casting vs Bracing for Idiopathic Early-Onset Scoliosis

CVBT
Start date: February 9, 2021
Phase: N/A
Study type: Interventional

Comparison of casting and bracing for the treatment of idiopathic early onset scoliosis

NCT ID: NCT04461964 Withdrawn - Scoliosis Clinical Trials

Effects of a Spine Navigation System on Op-time and Radiation Exposure

Start date: July 2022
Phase: N/A
Study type: Interventional

The goal of this study is to prospectively collect information about the operative time and intraoperative radiation experienced by patients undergoing posterior spinal fusion procedures guided by the MvIGS spine navigation system.

NCT ID: NCT04441411 Recruiting - Clinical trials for Adolescent Idiopathic Scoliosis

Non Fusion Surgery in Adolescent Idiopathic Scoliosis Patients

NEMOST-AIS
Start date: June 1, 2020
Phase: N/A
Study type: Interventional

The primary objective of the study is to monitor the effectiveness of a minimal invasive non-fusion double rod bipolar posterior spinal implant (Nemost growing domino) to correct the scoliotic curve in growing patients suffering from progressive adolescent idiopathic scoliosis (AIS) who have failed conservative treatment.

NCT ID: NCT04423146 Recruiting - Scoliosis Clinical Trials

Anesthesiologic Management Effect on Perioperative Outcome in Scoliosis Surgery

SCOL
Start date: September 1, 2020
Phase:
Study type: Observational

Alteration of evoked potentials is described in cases with using inhalation anaesthetics. Muscle relaxants are contraindicated in case of motor evoked potentials except for initial dose for intubation of the patient. Dominant anaesthetic method for procedures with measuring motor evoked potentials is total intravenous anaesthesia (TIVA). Bispectral index (BIS) monitoring is one of the possible options for comprehensive monitoring of the depth of general anaesthesia. It helps to optimize the management of anaesthesia, so it reduces the risk of perioperative awakenings due to shallow anaesthesia or inadequate depth of anaesthesia associated with the risk of cognitive dysfunction, as well as investigators expect worse interpretation of motor evoked potentials. At the same time, it shortens the time to wake up from general anaesthesia after hours-long surgery. BIS monitoring allows optimizing the depth of anaesthesia and leads to improve quality and interpretation of motor evoked potentials. The depth of TIVA managed by BIS affects the reproducibility of motor evoked potentials.

NCT ID: NCT04421157 Completed - Clinical trials for Adolescent Idiopathic Scoliosis

Exercises in Adolescent Idiopathic Scoliosis

Start date: October 17, 2019
Phase: N/A
Study type: Interventional

The purpose of this study was to investigate the effectiveness of two different exercises in adolescent idiopathic scoliosis. In total, 28 subjects with adolescent idiopathic scoliosis were randomly divided into two groups: Schroth (n = 14) and stabilization group (n = 14). The Schroth group received Schroth exercises in addition to traditional rehabilitation, and the stabilization group received core stabilization in addition to traditional rehabilitation for 10 weeks. The outcome measures were based on Cobb angle, angle of trunk rotation, spinal mobility, cosmetic trunk deformity, muscle strength, and quality of life.