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Scar clinical trials

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NCT ID: NCT04046679 Not yet recruiting - SCAR Clinical Trials

Bleomycin Infusion (MMP®) to Repigment Achromic Scars

MMP®
Start date: August 31, 2019
Phase: Phase 4
Study type: Interventional

This intervention, called MMP®, is a procedure whereby drugs are injected through tattoo machines.

NCT ID: NCT04015453 Completed - Quality of Life Clinical Trials

Correlation of Early Postoperative Scar Appearance With Long-term Scar Outcomes

Start date: July 2016
Phase:
Study type: Observational

A retrospective cohort study of early and late period postoperative scars using previously validated survey measures and clinical photographs. The target population consists of participants treated with Mohs micrographic surgery (MMS) for a facial skin cancer by the division of dermatologic surgery. This study aims to determine if patient assessment of scar appearance correlates with physician ratings and/or third-person observer ratings. Secondary goals are to assess for correlations between early post-operative scar appearance and long-term scar appearance as well as identification of predictive factors for scar healing.

NCT ID: NCT03936309 Recruiting - Scar Clinical Trials

A Comparison of Scar Infiltration, Scar Deactivation, and Standard of Care for the Treatment of Chronic, Post-Surgical Pain After Cesarean Section

Start date: June 1, 2019
Phase: N/A
Study type: Interventional

To compare scar infiltration with 0.5-1% Lidocaine at a dose of 3 mg/kg (max dose 300 mg) or scar deactivation with acupuncture surface release technique to determine which is more effective in reducing pain in adult patients with chronic, post-surgical pain related to the site of incision after low transverse Cesarean section compared to standard of care physical therapy with the McKenzie Method.

NCT ID: NCT03888703 Completed - Burns Clinical Trials

The Use of Fractional Ablative CO2 Laser vs Control on Acute Traumatic Injuries to Prevent Scar Formation

Start date: May 4, 2015
Phase: N/A
Study type: Interventional

Surgical standard for treating traumatic burn injury scarring is to wait one year following the initial assault prior to beginning treatment. This study investigates the use of fractional ablative CO2 laser when begun within 3 months of a traumatic burn injury and it's impact on scar formation compared to the control. We hypothesized that early intervention would substantially mitigate the formation of scar tissue and help restore more normal appearing skin.

NCT ID: NCT03887377 Enrolling by invitation - Scar Clinical Trials

The Efficacy and Molecular Mechanism of Botulinum Toxin in the Reduction of Breast Reduction Mammoplasty Scar Formation

Start date: June 10, 2019
Phase: Phase 2/Phase 3
Study type: Interventional

1. Test the ability of botulinum toxin type A, when injected into the surgical incision at the time of surgery, to decrease postoperative scar scores compared to control (normal saline) in a double-blinded randomized control trial. 2. Investigate the mechanism of BTXa effects of scar formation by measuring micro RNA profiles at two time points in the healing process.

NCT ID: NCT03887208 Completed - Scar Clinical Trials

Therapy of Scars and Cutis Laxa With Autologous Adipose Derived Mesenchymal Stem Cells

2ABC
Start date: January 31, 2018
Phase: Phase 1/Phase 2
Study type: Interventional

The aim of this study is to compare clinical outcomes of patients with large scars or Cutis laxa treated with injections of autologous stromal vascular fraction cells (SVF) and adipose-derived mesenchymal stem cells (ADSC).

NCT ID: NCT03842644 Completed - Scar Clinical Trials

Postoperative Skin Surface Tension Relaxing in Prevention of Facial Surgical Skin Scarring

Start date: February 16, 2019
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of early postoperative skin surface reduction in improving scar formation after facial surgery.

NCT ID: NCT03795116 Completed - Fibrosis Clinical Trials

Light Emitting Diode-Red Light (LED-RL) Phototherapy for Skin Scarring Prevention

Start date: March 18, 2019
Phase: Phase 2
Study type: Interventional

Skin scarring (fibrosis) is a common complication in the wound healing process and remains a therapeutic challenge. Scar formation often occurs following injury to the skin such as surgery, trauma, and burns. The goal of this study is to evaluate the safety and efficacy of visible red light as a modality to reduce skin scarring after mini-facelift surgery. Based on laboratory data, light emitting diode-red light (LED-RL) phototherapy may lessen post-surgical skin fibrosis clinically.

NCT ID: NCT03732599 Enrolling by invitation - Keratoconus Clinical Trials

Comparison Between Standard Deep Anterior Lamellar Keratoplasty (S-DALK) and Intralase Enabled Deep Anterior Lamellar Keratoplaty (IE-DALK)

Start date: April 8, 2015
Phase: N/A
Study type: Interventional

A prospective comparison between standard deep anterior lamellar keratoplasty (S-DALK) performed manually using a blade (trephine) and femtosecond laser-enabled deep anterior lamellar keratoplasty (IE DALK), where incisions are performed using the femtosecond laser.

NCT ID: NCT03646955 Recruiting - Pain Clinical Trials

Partial Breast Versus no Irradiation for Women With Early Breast Cancer

Start date: September 5, 2018
Phase: N/A
Study type: Interventional

All early breast cancer patients are offered adjuvant breast radiation therapy (RT) after breast conserving surgery for an early breast cancer. Breast cancer is heterogeneous, and selected patients have a very low gain from RT, whilst they still have risk of acute and late side effects from RT. This trial will try identify selection criteria for low risk breast cancer patients who can safely omit adjuvant RT without unacceptable high risk of local failure.