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Scar clinical trials

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NCT ID: NCT06386549 Recruiting - Burns Clinical Trials

Effect of a Tele-rehabilitation Programme in Children With Burns: a Randomized Controlled Trial

Start date: November 14, 2022
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to compare tele-rehabilitation and routine post-discharge rehabilitation in children with burn injuries. The main questions it aims to answer are: - Is tele-rehabilitation better for improving the quality and outcomes of care for burn children? - Is tele-rehabilitation more effective in improving scar management in children with burns injuries? - Is tele-rehabilitation more effective in improving perceived stress in parents of children with burns injuries?

NCT ID: NCT06117293 Recruiting - Acne Vulgaris Clinical Trials

Safety and Efficacy Evaluation of the Mosaic Ultra Device

Start date: February 21, 2023
Phase: N/A
Study type: Interventional

Evaluate the Safety and Efficacy of the Mosaic Ultra 1550nm system for the treatment of skin tone and texture, facial rejuvenation, photoaging, wrinkles, scars, stretch marks, acne vulgaris and hair loss.

NCT ID: NCT05838833 Recruiting - Scar Clinical Trials

Ointment to Prevent Scar After Thyroidectomy

Start date: February 14, 2023
Phase: Phase 2
Study type: Interventional

The goal of this study is to evaluate the efficacy and Safety of INV-001 administration for the prevention of scar after thyroidectomy. Participants will be asked to apply ointment on their scar for 12 weeks.

NCT ID: NCT05501327 Recruiting - Wound Healing Clinical Trials

Dose Regimen Study of SLI-F06 in Healthy Volunteers

Start date: July 25, 2022
Phase: Phase 2
Study type: Interventional

Multi-center, dose-regimen, double-blind study evaluating the safety and efficacy of 4 doses of SLI-F06 compared with vehicle for improvement in scar appearance

NCT ID: NCT05408117 Recruiting - Scar Clinical Trials

Impact of Suture Type on Pigment Disturbances in Patients of Skin of Color

Start date: October 1, 2022
Phase: N/A
Study type: Interventional

The present study assesses if dissolvable (fast gut) or non-dissolvable (polypropylene) epidermal sutures produce better cosmetic results in terms of dyspigmentation and scarring in patients of skin of color. Through a split-wound study design, patients undergoing standard elliptical excisions at least 3 cm in length will receive each suture type. Measurements of dyspigmentation and scarring will be made at 7 days (for the head and neck), 10 days (for the trunk and extremities), and 3 months for all locations.

NCT ID: NCT05267002 Recruiting - Surgery Clinical Trials

Comparing 1 Week Versus 2 Week Cutaneous Suture Removal

Start date: February 24, 2022
Phase: N/A
Study type: Interventional

Our goal is to compare the difference in surgical outcomes and patient satisfaction for surgical scars on the face between suture removal at 1 week versus 2 weeks. There is variation in the timing at which Mohs surgeons remove sutures on the face. Some prefer 1 week, and others prefer 2 weeks. This has not been formally studied. It is possible the outcomes are the same between both groups, or that one has a better cosmetic outcome than the other. Your skin cancer will be removed as usual. After this, your wound will be sutured in the usual fashion, except the top sutures will be divided into two separate halves. You will return at 1 week for one half of the top sutures to be removed, and at 2 weeks for the other half to be removed. Which half is removed first will be determined at random at your 1 week visit. At two months, you will return for standardized photographs which will be used by physicians to rate the cosmetic outcomes of the wound halves based on a standardized scale. Most likely, there will be no difference between the wound halves at 2 months and the study is complete. There is a small chance that there will be a cosmetic difference seen at 2 months, in which case you will return at 1 year for repeat standardized photographs and ratings. All data and photographs will be kept secure and any identifying information will be destroyed at the end of the study.

NCT ID: NCT05074238 Recruiting - Wound Heal Clinical Trials

Influence of Sun Protection and Linear Repair of Cutaneous Surgical Defects

Start date: July 16, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the potential influence of sun protection on the aesthetic outcome of post-surgical scars following the reconstruction of Mohs micrographic surgery defects via linear repair. This study will be performed as a randomized split-wound study. Half of the wound will be treated with zinc containing sunscreen and the other half of the wound would not be treated. Three-months post-surgery, the scar will be evaluated via the patient observer scar assessment scale (POSAS), a validated scar instrument, as well as a colorimeter to measure the amount of vascularity, and hyperpigmentation between the treated and the non-treated area compared to the 'surrounding skin' defined as skin in the proximity but not adjacent to the wound. Any adverse events will also be recorded.

NCT ID: NCT05003869 Recruiting - Scar Clinical Trials

Clinical and Basic Research on the Necessity of Scar Tissue Resection During Intrauterine Adhesions

Start date: May 25, 2021
Phase: N/A
Study type: Interventional

TCRA is an important surgical method to restore normal menstrual cycle and improve the outcome of pregnancy.However, postoperative intrauterine adhesion, uterine cavity deformation and difficulty in normal intimal growth seriously affect the efficacy of surgery. A large number of existing studies have shown that even after surgical treatment, women with a history of IUA are still at a reproductive disadvantage.Whether scar tissue plays a role in these influencing factors? At present, there is a variety of surgical methods, and there is no clear guideline consensus on how to deal with intrauterine scar tissue during surgery.

NCT ID: NCT04736251 Recruiting - Scar Clinical Trials

Mechanistic Basis of Ablative Carbon Dioxide Laser in Treating Hypertrophic Scars

SMOOTH
Start date: December 9, 2019
Phase:
Study type: Observational

This is an observational cohort study which will look at the biomarkers from blood and tissue sample for adult patients with hypertrophic scarring due to burns/trauma incident over 12 months from date of recruitment. The study will assess the kinetics of the response to fractionated carbon dioxide laser therapy in hypertrophic scars.

NCT ID: NCT04506255 Recruiting - Scar Clinical Trials

Silicone Taping for the Improvement of Abdominal Donor Site Scars

Start date: November 16, 2020
Phase: N/A
Study type: Interventional

This study will look at silicone tape compared to the current no dressing standard at the investigators institution, to determine if silicone tape provides a significant improvement in post-abdominoplasty scar appearance. Silicone tape will be added to half of the abdominoplasty incision of patients undergoing abdominally-based breast reconstruction procedures two weeks after their operation. They will be followed up and assessed at specific timepoints to determine whether the silicone improves scar outcomes in these patients.