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Reproductive Disorder clinical trials

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NCT ID: NCT06357208 Not yet recruiting - Clinical trials for Reproductive Disorder

IMPACT OF BREATH CONTROL AND RETENTION ON PATIENT STRESS. E.S IN MEDICALLY ASSISTED REPRODUCTION BREATH HOLD TO BREATH BETTER PROGRAM

BHBB
Start date: May 1, 2024
Phase: N/A
Study type: Interventional

we propose for patient in the course of Medically Assisted Reproduction a study with to arm: one arm active "Breathing Control and Retention" and the other arm control

NCT ID: NCT05971849 Recruiting - Clinical trials for Polycystic Ovary Syndrome

Dampening the Reproductive Axis With Continuous Kisspeptin

Start date: October 6, 2023
Phase: Phase 1
Study type: Interventional

The goal of this study is to assess response to kisspeptin as well as the baseline patterns of luteinizing hormone (LH) secretion in individuals with polycystic ovarian syndrome (PCOS).

NCT ID: NCT05971836 Recruiting - Clinical trials for Hypogonadotropic Hypogonadism

The Molecular Basis of Inherited Reproductive Disorders

Start date: January 21, 2021
Phase:
Study type: Observational

The goal of this study is to learn more about the genes that control puberty and reproduction in humans.

NCT ID: NCT05901467 Terminated - Clinical trials for Reproductive Disorder

Recall by Genotype: Neuropeptide Stimulation

Start date: October 20, 2023
Phase: Phase 1
Study type: Interventional

The objective of this protocol is to assess response to kisspeptin and gonadotropin-releasing hormone (GnRH) stimulation testing as well as the baseline patterns of luteinizing hormone (LH) secretion in individuals who carry variants in genes related to infertility.

NCT ID: NCT05866484 Active, not recruiting - Infertility, Male Clinical Trials

Testicular Sperm Aspiration (TESA) vs. Microfluidic Sperm Separation (MSS)

TESA vs Zymot
Start date: May 10, 2023
Phase:
Study type: Observational

Normal embryonic development relies on the correct transmission of genetic information, and sperm DNA plays a crucial part in this process. Causes of poor sperm DNA integrity include unhealthy lifestyles such as smoking and exposure to gonadotoxins, as well as, obesity, varicoceles, infections, advanced paternal age and systemic disorders. An increase in DNA fragmentation in sperm has been linked to lower fertilisation rate, poorer quality embryos, lower pregnancy rate, and high miscarriages rate. The best way for sperm selection and processing in assisted reproductive technologies (ART) should be noninvasive and cost-effective. It should also make it possible to identify high-quality spermatozoa and produce more favorable results in terms of pregnancy and live birth rates.7 Meanwhile, the microfluidic sperm separation technology is a less expensive and less invasive alternative. This method allows for the selection of motile sperm that have a normal morphology, low levels of reactive oxygen species (ROS), and low DFI

NCT ID: NCT05788822 Recruiting - Infertility, Female Clinical Trials

MVA to Improve the Pregnancy Outcome in Aged Infertility Women With Assisted Reproductive Technology

Start date: October 8, 2022
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to test MVA on improving pregnancy outcome in elderly infertile patients undergoing invitro fertilization (IVF). The main question it aims to answer is whether MVA could improve embryo haploid rate. Participants requested IVF are asked to randomly culture equal numbers of oocyte and embryo with or without MVA. Therefore, sibling oocytes were randomly divided into test group and control group.

NCT ID: NCT05506800 Suspended - Breast Cancer Clinical Trials

Guangzhou Women's Health Cohort Study (GWHCS)

Start date: March 3, 2016
Phase:
Study type: Observational

The Guangzhou Women's Health Cohort Study aims to explore the health trajectory and factors contributing to the health of women aged 35-64 in Guangzhou. Based on multiple population health registration data platforms, data of the cohort will provide information about the health of women across the lifespan, facilitating the decision-making process by local government . The cohort is progressing steadily, and the goal is to build a large women cohort covering 11 administrative districts of Guangzhou with a scale of 1 million by 2030.

NCT ID: NCT04854707 Completed - IVF Clinical Trials

An Observational Study of Follitropin Alpha Biosimilar: the Real-world Data

Start date: January 12, 2020
Phase:
Study type: Observational

Aim to investigate the efficacy of follitropin alpha biosimilar therapy (Primapur®) in nonselected real-world population.

NCT ID: NCT04361292 Completed - Infertility Clinical Trials

Ejaculatory Abstinence in IUI Cycles

Start date: January 1, 2019
Phase: N/A
Study type: Interventional

Intrauterine insemination (IUI) combined with ovarian stimulation, has been an extensively used procedure for the treatment of patients with unexplained infertility. The aim of this study was to report the effect of ejaculatory abstinence on sperm DNA fragmentation and pregnancy rates in IUI cycles, as well as the correlation between the two.

NCT ID: NCT03922087 Completed - Obesity Clinical Trials

No-worry Baby Project

Start date: November 20, 2018
Phase:
Study type: Observational

The Huizhou mother-infant cohort was set up to investigate the effect of dietary factors and environmental exposures during pregnancy on health consequences of mothers and offsprings in Huizhou, China.