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Recurrence clinical trials

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NCT ID: NCT06113575 Completed - Clinical trials for Major Depressive Disorder

Practical Application of Accelerated iTBS for MDD

Start date: November 23, 2022
Phase: N/A
Study type: Interventional

The goal of this observational study is to evaluate the feasibility and efficacy of accelerated iTBS in adults diagnosed with Major Depressive Disorder. The main question it aims to answer is: What is the efficacy and tolerability of an accelerated iTBS regimen without radiological imaging in adults who have been diagnosed with Major Depressive Disorder and experience treatment resistant symptoms? Participants will complete 36 iTBS treatments in an accelerated schedule over five days. They will also complete several clinical assessments throughout their enrollment to evaluate their depressive symptoms and response to treatment.

NCT ID: NCT06102551 Completed - Incisional Hernia Clinical Trials

A Retrospective Analysis of Incisional Hernia Repair's Postoperative Recurrence

Start date: March 1, 2023
Phase:
Study type: Observational

ABSTRACT Purpose:A retrospective study was conducted among patients with incisional hernia in our hospital to analyse the factors associated with postoperative recurrence of abdominal wall incisional hernia. Methods:Patients with a diagnosis of incisional hernia obtained from our hospital's electronic medical record system were divided into primary incisional hernia group and recurrent incisional hernia group according to whether or not they had a recurrence after surgery. Baseline information on these patients was recorded and statistically analysed after our review.

NCT ID: NCT06081556 Completed - Clinical trials for Recurrent Spontaneous Abortion

Difference Between Mean Gestational Sac Diameter and Crown-rump Length as a Marker of First-trimester Pregnancy Outcome in Patients With Recurrent Spontaneous Abortion

mGSD-CRL& RSA
Start date: January 1, 2020
Phase:
Study type: Observational

Objective: To determine the effect and predictive value of the difference between the mean gestational diameter (mGSD) sac and crown-rump length (CRL) of the first trimester on the pregnancy outcomes of patients with recurrent spontaneous abortion (RSA).Methods: This is a retrospective cohort study. In total, 256 pregnant women at 6-10 weeks of gestation and with RSA who visited our hospital from January 2020 to March 2023 were included in the study. They were divided into the following three groups based on the difference between the mGSD and CRL (mGSD-CRL): Group A: mGSD-CRL ≥ 10mm, 41 cases; Group B: 10mm < mGSD-CRL ≤ 15mm, 109 cases; and Group C: mGSD-CRL > 15mm, 106 cases.

NCT ID: NCT06059625 Completed - Clinical trials for Cuff Injury, Rotator

RECURRENCE OF ROTATOR CUFF LESION AFTER SURGICAL REPAIR WITH SINGLE-ROW vs DOUBLE-ROW SUTURE BRIDGE TECNIQUE: A COMPARATIVE STUDY

Start date: April 14, 2021
Phase: N/A
Study type: Interventional

The rotator cuff is a muscle-tendon complex consisting of the tendons of the supraspinatus, subspinatus, subscapularis, and small round muscles capable of allowing movement of the shoulder joint in the various planes of space and stabilizing the glenohumeral joint. Rotator cuff tendon injuries are very common. In most cases, these injuries are mostly degenerative based, as they are related to the aging process of the individual. However, it is increasingly common to diagnose such injuries in young individuals as well. The reported incidence of rotator cuff injuries ranges from 5% to 40%, and of course the prevalence increases with age until it reaches 51% in patients older than 80 years. The diagnosis of rotator cuff injury is made based on clinical examination and instrumental investigations such as Nuclear Magnetic Resonance Imaging (MRI). Rotator cuff repair involves the use of anchors with included suture threads that allow the tendons to be returned to the level of the anatomical insertion, called the footprint. Suture technique varies depending on the extent of injury and tendon and bone quality. Single-row (single row) or double-row suture bridge (double-row suture bridge) anchoring techniques are currently a hotly debated topic in the literature.

NCT ID: NCT06050538 Completed - Clinical trials for Recurrent Inguinal Hernia

Laparscopic Hernioplasty in Recurrent Inguinal Hernia

Start date: February 1, 2021
Phase: N/A
Study type: Interventional

The purpose of this study was to compare between laparoscopic transabdominal preperitoneal (TAPP) and totally extraperitoneal (TEP) repair of inguinal hernia in recurrent inguinal hernia.

NCT ID: NCT06036576 Completed - Thyroid Diseases Clinical Trials

Thyroxine Therapy for Recurrent Pregnancy Loss in Hypothyroid Women

Start date: March 1, 2022
Phase: Phase 3
Study type: Interventional

The goal of this clinical trial is to investigate the influence of thyroxine supplementation on pregnancy outcomes in women with varying levels of Thyroid-Stimulating Hormone (TSH), who have experienced recurrent pregnancy loss in the first trimester. The main questions it aims to answer are: - Does thyroxine treatment improve pregnancy outcomes in women with TSH levels between 2.5 mU/L and 4 mU/L? - Is the effect of thyroxine treatment different in women with TSH levels higher than 4 mU/L? Participants will be grouped based on their TSH levels, into two groups - those with TSH levels between 2.5 mU/L and 4 mU/L, and those with TSH levels higher than 4 mU/L. They will then be given thyroxine treatment. Researchers will compare these two groups to see if the pregnancy outcomes differ based on the different TSH levels and thyroxine treatment.

NCT ID: NCT06008535 Completed - Chronic Pain Clinical Trials

10-year Results of Open Inguinal Hernia Repair

Start date: May 22, 2018
Phase:
Study type: Observational

The main goal of the research is to evaluate the long-term results of open anterior alloplasty of inguinal hernia, mainly the occurrence of recurrences. The secondary aim of the study is to clarify the incidence of chronic pain and foreign body sensation 10 years after inguinal hernia surgery. Patients who meet the criteria for inclusion in the study are invited to an appointment, where a questionnaire is filled out, an clinical examination and an ultrasound examination are performed.

NCT ID: NCT06002035 Completed - Clinical trials for Vitamin D Deficiency

Study on Clinical Value of Vitamin D in Recurrent Spontaneous Abortion

Start date: January 1, 2021
Phase:
Study type: Observational

The observational study is to compare vitamin D deficiency and related indicators among different spontaneous abortions in describe female reproductive health.The main question aim to answer is: the possible pathogenesis of recurrent spontaneous abortion caused by vitamin D. Participants, who visit the RSA specialty clinic, will provide medical history information, regularly exam based on the condition, following up on pregnancy status.Participants will be asked to supply vitamin D preparation and do moderate exercise outdoors, comparing the effect after treatment.

NCT ID: NCT06000306 Completed - Clinical trials for Measurable Residual Disease

MRD Monitoring by Digital Droplet PCR in the Early Period After Allo-HSCT to Predict Patients at High Risk of Relapse

Start date: January 1, 2018
Phase:
Study type: Observational

A study on the Effectiveness of digital droplet PCR in monitoring measurable residual disease during the early period after allogeneic hematopoietic stem cell transplantation to predict patients at high risk of relapse

NCT ID: NCT05998421 Completed - Acupuncture Clinical Trials

The Effects of Acupuncture on the Natural Pregnancy in Patients With Recurrent Abortion

Start date: March 1, 2022
Phase: N/A
Study type: Interventional

Recurrent spontaneous abortion (RSA) is a common pregnancy complication in women of reproductive age and the cause of RSA remains largely unclear. Acupuncture is widely used in clinical practice to treat infertility and abortion. The role of acupuncture in the treatment of infertility is still unclear. The investigators conducted a randomized, prospective, controlled clinical trial to investigate its potential impact on pregnancy outcome. Herein, the investigators not only evaluated the changes in patients' psychological stress before and after treatment but also followed up on pregnancy outcomes. In addition, changes in uterine artery blood flow were observed by ultrasound. Changes in coagulation-related indicators were also detected.