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Pulpitis clinical trials

View clinical trials related to Pulpitis.

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NCT ID: NCT04374214 Active, not recruiting - Reversible Pulpitis Clinical Trials

Effect of Simvastatin as Pulpotomy Agent in Cariously Exposed Permanent Molars

Start date: December 1, 2018
Phase: N/A
Study type: Interventional

The study will compare the outcome of complete pulpotomy in mature permanent mandibular molars with deep carious lesions by using Mineral Trioxide Aggregate and Simvastatin -alpha tricalcium phosphate as medicament agent

NCT ID: NCT04365270 Completed - Caries Clinical Trials

Antibacterial Effect and Clinical Performance of Chitosan Modified Glass Ionomer

Start date: January 15, 2019
Phase: Phase 3
Study type: Interventional

The study is a randomized clinical trial that assesses the clinical success and the antibacterial effect on carious dentine of glass ionomer when modified with Chitosan and/or Titanium dioxide nano particles vs the control group of modification with Chlorhexidine as control when used in primary molars

NCT ID: NCT04331964 Completed - Pulpitis Clinical Trials

The Use of Platelet-Rich Fibrin in Partial Pulpotomy Procedure

Start date: May 1, 2020
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the clinical and histological pulp responses when MTA and a combined of MTA/PRF is used as pulp-capping agents after partial pulpotomy.

NCT ID: NCT04319549 Not yet recruiting - Clinical trials for Acute Irreversible Pulpitis With Apical Periodontitis

Ketorolac Irrigant on Post Operative Pain

Start date: August 1, 2020
Phase: N/A
Study type: Interventional

Endodontic post-treatment pain management is one of the most challenging problems in the clinical practice of endodontics. Although this pain is decreased after root canal treatment, there may be residual symptoms due to inflammation. It has been reported that up to 80% of patients with preoperative pain, will report pain after endodontic treatment, which might range from mild to severe. Management of endodontic pain should involve all steps of treatment including preoperative pain control through accurate diagnosis and reduction of anxiety, intraoperative pain control through effective and profound local anesthetic, operative techniques and that can be achieved through a variety of pharmacologic agents. Many mechanisms have been proposed to explain the reason for postoperative pain including the sensitization of nociceptors by inflammatory mediators. Among these chemical inflammatory mediators are the prostaglandins which is the terminal product of arachidonic acid metabolism, through the cyclooxygenase (COX) pathway. Endodontic treatment can cause the release of inflammatory mediators (e.g. prostaglandins, leukotrienes, bradykinin, platelet- activating factor and substance P) into the surrounding periapical tissues, causing pain fibers to be directly stimulated (by bradykinin for instance) or sensitized (by prostaglandins). In addition, the vascular dilation and increased permeability as a consequence of periradicular inflammation, cause edema and increased interstitial tissue response. Single-visit root canal treatment is common in some endodontic practices. However, one of the main concerns with this approach has been the fear of post- operative pain. Mechanical, chemical and microbiological injuries to the peri- radicular tissues during root canal treatment have been suggested as possible causes of post-operative pain. The role of irrigating solutions used during root canal treatment to help control post-operative pain is unclear. While certain studies have observed a reduction in post-operative pain with particular types and concentrations of irrigating solutions, other studies have reported no difference in post-operative pain with the different irrigating solutions .

NCT ID: NCT04308863 Completed - Clinical trials for Pulpitis - Irreversible

Evaluation of Chitosan Scaffold and Mineral Trioxide Aggregate Pulpotomy in Mature Permanent Molars With Irreversible Pulpitis

Start date: November 15, 2018
Phase: Phase 2
Study type: Interventional

The aim of this study is to evaluate the clinical and radiographic outcomes of Chitosan scaffold and Mineral trioxide aggregate (MTA) when used as pulpotomy agents in mature permanent teeth with irreversible pulpitis.

NCT ID: NCT04243733 Recruiting - Clinical trials for Irreversible Pulpitis

MTA vs CEM Pulpotomy in Young Permanent Molars

Start date: October 10, 2018
Phase: N/A
Study type: Interventional

The aim of the study The purpose of this present clinical study will be to assess : " the successful clinical outcome of CEM cement in comparison to MTA in the pulpotomy of young permanent molar teeth with irreversible pulpitis . " the successful radiographic outcome of CEM cement in comparison to MTA in the pulpotomy of young permanent molar teeth with irreversible pulpitis.

NCT ID: NCT04228913 Completed - Pain Clinical Trials

Effect of Different Obturation Techniques on Postoperative Pain

Start date: August 31, 2017
Phase: Phase 4
Study type: Interventional

This study evaluated the postoperative pain after the endodontic treatment by using three different obturation techniques. ( Cold lateral condensation (CLC), thermoplasticized solid-core carrier method (GuttaCore) and cold free-flow compation tecnique ( GuttaFlow2))

NCT ID: NCT04211519 Completed - Endodontic Disease Clinical Trials

Analysis of Bacterial Microbiome of Endodontically Infected Primary and Permanent Teeth

Start date: September 1, 2017
Phase: N/A
Study type: Interventional

Recognition of community profiles in endodontic infections may allow a better understanding of the pathogenesis of the disease and the establishment of more effective treatment protocols. Therefore, the aim of the present study was to investigate bacterial diversity in endodontically infected primary and permanent teeth using 16S rRNA gene sequencing and QIIME 2TM (Quantitative Insights Into Microbial Ecology 2) bioinformatics pipeline

NCT ID: NCT04202406 Completed - Clinical trials for Symptomatic Irreversible Pulpitis

Preoperative Acetaminophen- Caffeine- Codeine Combination and Anaesthetic Success in Patients With Acute Pulpitis

Start date: January 9, 2021
Phase: N/A
Study type: Interventional

The aim of the study is to evaluate the effect of preoperative administration of acetaminophen- codeine -caffeine combination on the success of the inferior alveolar nerve block versus bacetaminophen alone or placebo in patients with symptomatic irreversible pulpitis.

NCT ID: NCT04186897 Completed - Clinical trials for Symptomatic Irreversible Pulpitis

Occlusal Reduction Effect on Postendodontic Pain

Start date: September 2014
Phase: N/A
Study type: Interventional

The aim of this study, thus, was to assess the effect of occlusal reduction on postendodontic pain after the first (post-instrumentation) and the second (post-obturation) visit in mandibular posterior teeth with symptomatic irreversible pulpitis and sensitivity to percussion treated in two visits.