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Caries clinical trials

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NCT ID: NCT06231823 Recruiting - Caries Clinical Trials

Extraction of the Compromised First Permanent Molars

FPM
Start date: January 1, 2024
Phase: N/A
Study type: Interventional

Compromised first permanent molars (FPM), whether diagnosed with severe molar incisor hypomineralization (MIH), irreversible pulpities, or necrosis, require frequent re-treatment consequently entering the restorative cycle, which leads to their inevitable extraction and implant placement. Extraction of compromised first permanent molars in 8-10-year-old children allows the mesial migration of the second permanent molars during their eruption, thereby favoring spontaneous space closure as a permanent solution.

NCT ID: NCT06140758 Completed - Caries Clinical Trials

Evaluation of the Anticaries Efficacy of Dentifrice Formulations Using an In-situ Model

Start date: July 31, 2023
Phase: N/A
Study type: Interventional

The primary objective is to compare the remineralization and demineralization inhibition potential of early subsurface carious lesions in enamel in situ after rinsing with six different aqueous slurries of toothpaste formulations.

NCT ID: NCT06140745 Completed - Caries Clinical Trials

Evaluation of Dentifrice Formulations to Remineralize Enamel and Dentine Subsurface Lesions in a Double-Blind In-Situ Clinical Trial

Start date: October 5, 2020
Phase: N/A
Study type: Interventional

To compare the remineralization and demineralization inhibition potential of early subsurface carious lesions in enamel in situ after rinsing with five different aqueous slurries of toothpaste formulations. Percent remineralization (%R), i.e. the % change in ΔZ values relative to ΔZd, will be the primary outcome measure.

NCT ID: NCT06098911 Not yet recruiting - Caries Clinical Trials

Modified Atraumatic Restorative Treatment Using CPP ACP

Start date: February 10, 2024
Phase: N/A
Study type: Interventional

To evaluate the clinical and radiographic success of using Casein Phosphopeptide Amorphous Calcium Phosphate (CPP-ACP) under glass ionomer restorations in atraumatic restorative treatment as a biomimetic approach in pediatric dentistry.

NCT ID: NCT06081816 Completed - Clinical trials for Periodontal Diseases

Third Molar: Caries, Periodontal Desease and Quality of Life

Start date: May 1, 2013
Phase:
Study type: Observational [Patient Registry]

Caries and periodontal disease are chronic diseases of the oral cavity. The incidence of caries and periodontal disease can vary depending on the position of the third molar, The aim of this study was to verify possible associations between oral health-related quality of life (QoL), periodontal disease, caries lesions and the position of the lower third molar.

NCT ID: NCT06072742 Completed - Inflammation Clinical Trials

Effect of Lifestyle on Caries and Apical Periodontitis

Start date: September 20, 2020
Phase:
Study type: Observational [Patient Registry]

This study aimed to link lifestyle factors (Mediterranean diet adherence, stress, sleep quality, physical activity) to caries and apical periodontitis in 149 university-based individuals. Data included clinical and radiographic assessments and lifestyle questionnaires. Statistical tests and logistic regression were employed to analyze the relationships between these factors and oral health conditions.

NCT ID: NCT06010732 Recruiting - Caries Clinical Trials

In Situ Comparison of the Remineralization Potential of Optimized Fluoride Dentifrice With Control Fluoride Dentifrice

Start date: October 2, 2023
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the remineralization potential of an optimized fluoride dentifrice to a control fluoride dentifrice in an in situ caries model.

NCT ID: NCT05960110 Recruiting - Caries Clinical Trials

Randomized Clinical Trial: Oral Health Package Law and Fluor Varnish Impact on Schoolchildren in Merida, Mexico

DBMX
Start date: June 22, 2023
Phase: Phase 3
Study type: Interventional

Study aimed at evaluating the impact on oral health of the "Ley del Paquete de Salud Bucal" (daily school brushing program) combined, or not, with the application of fluoride varnish in schoolchildren from 6 to 8 years old who attend public elementary schools in Mérida, Mexico. with a two-year follow-up (2023-2025).

NCT ID: NCT05748327 Active, not recruiting - Caries Clinical Trials

Trial With Two New Tooth-colored Restorative Materials in Class I/II Cavities

Start date: November 22, 2022
Phase: N/A
Study type: Interventional

This is a randomized-controlled clinical trial to investigate the success rate of two new tooth-colored restorative materials in class I and II cavities over 5 years according to FDI criteria scores (1, 2 and 3).

NCT ID: NCT05569850 Not yet recruiting - Gingivitis Clinical Trials

Efficacy of an Antibacterial Toothpaste and Patients' Satisfaction

Start date: November 1, 2022
Phase: N/A
Study type: Interventional

The primary objective of this randomized controlled clinical trial (RCCT) will be to compare the efficacy in reducing the quantity of Streptococcus mutans (S. Mutans) in saliva of a recently introduced toothpaste compared to a commercially available toothpaste. The secondary outcomes will be to assess patients' impression of the toothpastes (in terms of taste, satisfaction etc.), and to investigate potential changes in dentin hypersensitivity, plaque formation and gingival inflammation.