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Reversible Pulpitis clinical trials

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NCT ID: NCT05878249 Active, not recruiting - Reversible Pulpitis Clinical Trials

Role Of Wound Lavage in Direct Pulp Capping Of Permanent Teeth With Carious Exposure

Start date: November 1, 2022
Phase: N/A
Study type: Interventional

the purpose of the study is to investigate the outcome of wound lavage agents Sodium hypochlorite and Ethylenediaminetetraacetic acid (EDTA) in direct pulp capping of mature permanent teeth with carious exposure.

NCT ID: NCT05167123 Completed - Deep Caries Clinical Trials

Pulp Capping in Primary Molars Using TheraCal (LC)

Start date: September 1, 2019
Phase: Phase 4
Study type: Interventional

A randomized clinical trial that aims to evaluate clinical and radiographic success rates of indirect pulp capping and direct pulp capping in primary molars with reversible pulpitis using a light-cured tri-calcium silicate base material (TheraCal (LC)).

NCT ID: NCT05145686 Completed - Reversible Pulpitis Clinical Trials

The Role of Matrix Metalloproteinases on the Primary Teeth Pulpotomy Treatments

Start date: January 1, 2018
Phase: Phase 1/Phase 2
Study type: Interventional

Matrix metalloproteinases (MMPs) are important zinc enzyme group that responsible for reducing extracellular matrix components. It has been reported that MMPs play an important role in pulpal inflammation. The aims of this in vivo study was to compare the expression levels of MMP-2, -8 and -9 in primary molars with reversible and irreversible pulpitis and to compare the clinically and radiographically success of MTA and Biodentine materials at the end of 18 months.

NCT ID: NCT05144711 Recruiting - Caries Clinical Trials

Management of Deep Carious Lesions in Adults

Start date: October 3, 2021
Phase: N/A
Study type: Interventional

Dental caries is one of the most prevalent non-communicable disease. However, despite its prevalence there is no consensus on how much caries to remove prior to placing a restoration to achieve optimal outcomes. Evidence for selective compared to complete nonselective excavation suggests there may be benefit for selective removal in sustaining tooth vitality while histological studies reveal that the remaining dentine is actually infected and may cause loss of vitality in long term. The aim of this study is to randomly compare selective to non-elective excavation methods in carious mature permanent teeth with symptoms of reversible pulpitis

NCT ID: NCT04807244 Not yet recruiting - Clinical trials for Irreversible Pulpitis

Treatment of Deep Carious Lesions With Selective Caries Removal, Partial or Full Pulpotomy

Vitapulp
Start date: April 1, 2021
Phase: N/A
Study type: Interventional

The optimal treatment of deep caries lesions extended to the inner third of dentin is still under discussion. Cariologists prefer selective caries removal, meanwhile endodontists recommend partial pulpotomy. So far, no clinical trial compared both interventions against each other. Additionally, current literature indicates alternative treatment options for irreversible pulpitis besides conventional orthograde root canal treatments like the partial or full pulpotomy. Existing clinical studies on this topic were using different clinical protocols, especially with regards to the accepted time to achieve hemostasis. It is still unclear, if the pulpal bleeding time prior to the capping procedure affects the outcome of partial or full pulpotomy.

NCT ID: NCT04617600 Not yet recruiting - Reversible Pulpitis Clinical Trials

Survival Rate After TheraCal PT Pulpotomy Versus MTA Pulpotomy in Children With Vital Primary Molars.

Start date: March 1, 2022
Phase: N/A
Study type: Interventional

The aim of the study is to assess the effect of TheraCal PT pulpotomy versus MTA pulpotomy on the survival rate of cariously exposed vital primary molars.

NCT ID: NCT04374214 Active, not recruiting - Reversible Pulpitis Clinical Trials

Effect of Simvastatin as Pulpotomy Agent in Cariously Exposed Permanent Molars

Start date: December 1, 2018
Phase: N/A
Study type: Interventional

The study will compare the outcome of complete pulpotomy in mature permanent mandibular molars with deep carious lesions by using Mineral Trioxide Aggregate and Simvastatin -alpha tricalcium phosphate as medicament agent

NCT ID: NCT04365270 Completed - Caries Clinical Trials

Antibacterial Effect and Clinical Performance of Chitosan Modified Glass Ionomer

Start date: January 15, 2019
Phase: Phase 3
Study type: Interventional

The study is a randomized clinical trial that assesses the clinical success and the antibacterial effect on carious dentine of glass ionomer when modified with Chitosan and/or Titanium dioxide nano particles vs the control group of modification with Chlorhexidine as control when used in primary molars

NCT ID: NCT04167943 Completed - Reversible Pulpitis Clinical Trials

Conservative Pulp Therapy of Primary Molars Using TheraCAL

Start date: November 25, 2019
Phase: Phase 3
Study type: Interventional

The study is a clinical trial that assesses the clinical and radiographic success rates of 3 conservative pulp therapy treatments in primary molars compared to conventional pulpotomy using a bioactive dual cured calcium silicate cement (TheraCAL PT).

NCT ID: NCT03741816 Recruiting - Reversible Pulpitis Clinical Trials

Indirect Pulp Capping With Biodentine and TheraCal LC in Permanent Mature Molars

Start date: January 7, 2019
Phase: N/A
Study type: Interventional

Management of deep carious lesions in permanent mature molars with reversible pulpitis represents a challenge for clinicians. Vital pulp therapy includes indirect and direct pulp capping, partial pulpotomy and full pulpotomy. Indirect pulp capping is a procedure in which a material is placed on a thin layer of remaining soft dentin that, if removed, might expose the pulp. The objective is dentin bridge formation and pulp vitality preservation. The aim of this randomized clinical trial is to evaluate the success rate of indirect pulp capping with Biodentine and TheraCal LC in mature permanent molars with deep carious lesions at one-year follow-up examination. The null hypothesis tested will be that there is no statistically significant difference in success rate between both materials in indirect pulp capping of permanent mature molars with deep carious lesions.