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Pulpitis - Irreversible clinical trials

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NCT ID: NCT06201871 Recruiting - Clinical trials for Pulpitis - Irreversible

Effect of Alcohol Consumption on the Success Rates

Start date: January 2, 2024
Phase: N/A
Study type: Interventional

This prospective, randomized, double-blind clinical trial will be carried out Conservative Dentistry, Faculty of Dentistry, Jamia Millia Islamia. Seventy adult patients (35 alcoholic and 35 non-alcoholics) with symptomatic irreversible pulpits in a mandibular first or second molar will receive an IANB with 2% lidocaine. In case of pain during treatment, the procedure will be stopped, and the patients will be asked to rate the pain on the Heft-Parker scale. The injection shall be considered as successful if the patient reports pain scores less than 55 on the HP scale.

NCT ID: NCT06146686 Recruiting - Clinical trials for Pulpitis - Irreversible

Single Rotary File Pulpectomy in Primary Molars

Start date: February 1, 2024
Phase: N/A
Study type: Interventional

The aim of this study is to compare the clinical effectiveness of a single rotary file system versus a multiple rotary files system in pulpectomy of primary molars

NCT ID: NCT06002698 Recruiting - Clinical trials for Pulpitis - Irreversible

Full Pulpotomy Versus Root Canal Treatment for Teeth With Symptomatic Irreversible Pulpitis

Start date: August 8, 2023
Phase: N/A
Study type: Interventional

Background The European Society of Endodontology (ESE) and the American Association of Endodontists (AAE) position statements on the management of deep caries and exposed pulp recommended adoption and promotion of strategies aimed at preserving the pulp, but also acknowledged the need for well-designed and adequately powered randomised control trials to provide the evidence needed to support vital pulp treatment (VPT) and change clinical practice. Objectives 1. To undertake a randomised controlled clinical trial comparing full pulpotomy with root canal treatment for mature maxillary and mandibular posterior teeth with signs and symptoms indicative of irreversible pulpitis and normal apical tissues in adults. 2. Undertake a cost-effectiveness analysis to examine the potential long-term costs and benefits of pulpotomy. 3. Undertake a process evaluation to assess the acceptability of the intervention to both dentists and patients, while exploring the barriers and enablers to implementation.

NCT ID: NCT05902936 Recruiting - Clinical trials for Apical Periodontitis

Evaluation of Nano Bioactive Glass Combined With i-PRF Scaffold in Vital Pulp Treatments

Start date: March 1, 2023
Phase: N/A
Study type: Interventional

With consideration of the previous studies regarding the properties of i-PRF, it will be used in combination with another bioactive material: (Nano-BAG) versus using of i-PRF only as a pulpotomy material with using a premixed bioceramic putty as a coronal sealing material in both cases, to evaluate if there is a difference in the success rate of pulpotomy in case of using Nano-BAG in combination with i-PRF So, in this study the investigators will use Nano-BAG in combination with i-PRF as a material for pulpotomy in cases of mature permanent mandibular molars and compare its outcomes with using i-PRF only and in both cases pulpotomy material will be covered with a layer of premixed bioceramic putty for coronal sealing.

NCT ID: NCT05840913 Recruiting - Drug Effect Clinical Trials

Different Volumes of Articaine for Inferior Alveolar Nerve Block in Irreversible Pulpitis

IANB
Start date: April 30, 2023
Phase: Phase 2
Study type: Interventional

This is a randomized clinical trial comparing the anaesthetic efficacy of 1.8 and 3.6 mL of Articaine for inferior alveolar nerve block when treating mandibular molars with Irreversible Pulpitis

NCT ID: NCT05726357 Recruiting - Clinical trials for Pulpitis - Irreversible

Pulpotomy vs Root Canal Treatment for Teeth With Symptomatic Irreversible Pulpitis

Start date: April 1, 2023
Phase: N/A
Study type: Interventional

high-quality evidence is needed to add to current knowledge and also assess the long-term outcomes for full/complete pulpotomy after carious pulpal exposure in patients with signs and symptoms indicative of irreversible pulpitis

NCT ID: NCT05406557 Recruiting - Clinical trials for Pulpitis - Irreversible

Partial Versus Miniature Pulpotomy in Teeth With Irreversible Pulpitis

Start date: May 12, 2022
Phase: N/A
Study type: Interventional

This study will compare the outcome of partial and miniature pulpotomy in mature permanent molars with symptomatic partial irreversible pulpitis

NCT ID: NCT05402098 Recruiting - Clinical trials for Pulpitis - Irreversible

Outcome Following Endodontic Treatment Using Traditional Access Versus Conservative Access

Start date: May 12, 2022
Phase: N/A
Study type: Interventional

This study will compare the outcome of endodontic treatment using conservative or traditional access design in permanent molars with clinical signs indicative of irreversible pulpitis

NCT ID: NCT05336682 Recruiting - Clinical trials for Pulpitis - Irreversible

Evaluation of Lesion Sterilization and Tissue Repair Techniques Versus Pulpectomy in Primary Molars With Inflammed Pulp

Start date: September 20, 2022
Phase: N/A
Study type: Interventional

Group I (Experimental group I): Lesion Sterilization and Tissue Repair with radicular instrumentation. Coronal and accessible radicular pulp tissue are extirpated using rotary files. After proper drying, the paste is placed in the cavity and canals. Group II (Experimental group II): Lesion Sterilization and Tissue Repair with no radicular instrumentation. Only the coronal pulp is removed, the pulpal floor is covered with triple antibiotic paste with propylene glycol mix. Group III (Control group): Conventional pulpectomy. Pulp tissue extirpation is done. Biomechanical preparation is done using rotary files with frequent irrigation with Chlorhexidine. The canals are dried using sterile absorbent paper points followed by obturation by the paste of Zinc oxide and eugenol.

NCT ID: NCT05279781 Recruiting - Caries Clinical Trials

Outcome of Pulpotomy Versus Root Canal Therapy

Start date: April 1, 2019
Phase: N/A
Study type: Interventional

Root canal therapy (RCT) is indicated once the pulp is diagnosed with irreversible pulpitis. Despite favorable success rate reported for RCT in vital cases, it is time consuming, and might increases fracture susceptibility of teeth. With the advancement of materials and better understanding of pulpal healing, vital pulp therapy is practiced as an alternative treatment with high success rate. The aim of this study is to explore the outcome, quality of life and patient satisfaction after full pulpotomy compared to RCT.