Clinical Trials Logo

Clinical Trial Summary

To achieve painless treatment in patients with a failed primary IANB, supplementary anesthesia has been advised. The majority of the studies evaluating intrapulpal injections have been performed on asymptomatic teeth. Very limited research has been dedicated to the evaluation of different variables in intrapulpal injections in patients with symptomatic irreversible pulpitis. The aim of this study was to evaluate postoperative pain after an intrapulpal anesthesia injection given after a failed inferior alveolar nerve block (IANB), in patients with symptomatic irreversible pulpitis. This prospective, randomized, double-blind clinical trial was carried out at the Department of Conservative Dentistry and Endodontics, Faculty of Dentistry, Jamia Millia Islamia. One hundred and eight adult patients, with symptomatic irreversible pulpits in a mandibular first or second molar received an initial IANB with 2% lidocaine. Pain during the endodontic treatment was assessed using a visual analog scale (VAS). Patients experiencing pain on endodontic intervention were randomly allocated to one of the two treatment groups: one group received a supplementary intrapulpal injection while the other received a supplementary intraligamentary injection The presence of postoperative pain was assessed at 1, 2, 3, and 7 days after treatment.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT06088446
Study type Interventional
Source Jamia Millia Islamia
Contact
Status Completed
Phase N/A
Start date July 5, 2023
Completion date October 3, 2023

See also
  Status Clinical Trial Phase
Completed NCT06268912 - Cryoanalgesia for Irreversible Pulpitis N/A
Completed NCT06330519 - Impact of Different Techniques on The Efficacy of Anaesthesia in Mandibular Molars With Acute Irreversible Pulpitis Phase 4
Recruiting NCT05336682 - Evaluation of Lesion Sterilization and Tissue Repair Techniques Versus Pulpectomy in Primary Molars With Inflammed Pulp N/A
Recruiting NCT03956199 - Pulpotomy vs.Root Canal Treatment in Managing Irreversible Pulpitis N/A
Completed NCT03174860 - Effect of Preoperative Diclofenac Potassium on Articaine Buccal Infitration Success Phase 2/Phase 3
Completed NCT05853185 - Assessing Success of MTA and Pre-mixed Bioceramic in Mature Teeth With Irreversible Pulpitis With Full Pulpotomy. Phase 4
Not yet recruiting NCT03612323 - Comparison Between Intraligamentary Piroxicam and Articaine Early Phase 1
Not yet recruiting NCT02953912 - Assessment of Postoperative Pain Using Reciproc Versus One Shape Files in Patients With Irreversible Pulpitis N/A
Completed NCT04308863 - Evaluation of Chitosan Scaffold and Mineral Trioxide Aggregate Pulpotomy in Mature Permanent Molars With Irreversible Pulpitis Phase 2
Completed NCT04719247 - Clinical and Radiographic Evaluation of Turmeric, Thymus Vulgaris, Nigella Sativa and Aloe Vera as Pulpotomy Medicaments in Primary Teeth N/A
Completed NCT05582317 - Efficacy of Combination of Biodentine and Simvastatin as a Pulp Capping Materials in Vital Pulpotomy of Primary Molars N/A
Recruiting NCT05406557 - Partial Versus Miniature Pulpotomy in Teeth With Irreversible Pulpitis N/A
Recruiting NCT05402098 - Outcome Following Endodontic Treatment Using Traditional Access Versus Conservative Access N/A
Recruiting NCT05902936 - Evaluation of Nano Bioactive Glass Combined With i-PRF Scaffold in Vital Pulp Treatments N/A
Recruiting NCT03553407 - Analgesic Effect of Low Intensity Laser in Patients With Pulpitis of Mandibular Molars. N/A
Completed NCT05904184 - Comparison of Calcium Silicate-based Sealer and Epoxy Resin-based Sealer Phase 3
Not yet recruiting NCT03916900 - Postoperative Pain and Success Rate in Pulpotomy Versus Root Canal Treatment N/A
Enrolling by invitation NCT05964933 - Pulpotomy vs Root Canal Treatment for Teeth With Symptomatic Irreversible Pulpitis N/A
Withdrawn NCT04996641 - Endodontic-Restorative Pre-Radiation Therapy of Head and Neck Cancer Patients N/A
Not yet recruiting NCT02952300 - Post Operative Pain of Root Canal Preparation With Wave One and Neolix in Acute Irreversible Pulpitis N/A