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Pregnancy clinical trials

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NCT ID: NCT05685849 Recruiting - Pregnancy Clinical Trials

Evaluation of Maternal Fetal Cardiac Structure and Function in Pregnancies With Cardiovascular Disease

Start date: January 1, 2023
Phase:
Study type: Observational

The First Affiliated Hospital of China Medical University initiated a multi-center study to evaluate the changes of maternal fetal heart structure and function in pregnancies with cardiovascular disease by echocardiography, to explore the impact of cardiovascular disease on maternal fetal heart, so as to provide an important reference for obstetric pregnancy risk stratification and management.

NCT ID: NCT05681130 Completed - Pregnancy Clinical Trials

Effect of Depression, Anxiety and Stress Scores on Embryo Transfer Success

Start date: March 1, 2022
Phase:
Study type: Observational [Patient Registry]

Psychological status of couples attending to IVF programmes is important due to possible effect on final result. Observers aim to investigate the depression, anxiety and stress scores of couples before and after the procedure.

NCT ID: NCT05666297 Not yet recruiting - Pregnancy Clinical Trials

Screening of Cardiac Abnormalities in the First Trimester of Pregnancy by Volumetric Acquisition

Start date: December 20, 2022
Phase:
Study type: Observational

Ultrasound is one of the most important tools in pregnancy both for its diagnostic capacity, but also because it is not invasive. For physiological pregnancy, the Italian guidelines provide for the execution of 3 ultrasounds: one in the first trimester (between 11 and 14 weeks), one in the second trimester (between 20 and 22 weeks) and one in the third (between 30 and 36 weeks). weeks). Screening for cardiac abnormalities is done during second trimester ultrasound, also called structural ultrasound. However, the development of three-dimensional (3D) sonography has represented a dramatic shift in obstetrics as it allows for the acquisition of a volume of data rather than conventional planar or 2D scans. This method has allowed considerable progress in the study of the fetus in the initial stages of development and has opened new windows in the knowledge of anatomical malformations at an early age. The possibility of detecting structural anomalies already during the first trimester of pregnancy allows, in fact, to provide the patient with additional time for counseling and for any genetic tests.

NCT ID: NCT05656378 Recruiting - Pregnancy Clinical Trials

A Repository to Study Host-Microbiome Interactions in Health and Disease

Start date: March 9, 2023
Phase:
Study type: Observational

Background: The microbiome is the bacteria and other microorganisms that live inside and on the body. The microbiome is important for our health. Researchers study how the microbiome help people stay healthy. They study how the microbiome affects the body when people get sick. To do this research, they need samples of the microbiome living on the bodies of many people. The purpose of this natural history study is to collect microbiome samples in a repository. These samples will be used for future research. Objective: To collect microbiome samples from the body that can be used for future research. Eligibility: People of any age. Only those older than 3 years will be seen at the NIH clinic. Design: Participants will fill out a questionnaire. Topics will include their medical history and foods they eat. Participants will be asked to give 1 or more of the following: Stool, urine, saliva, vaginal fluid, and breastmilk. These samples can be collected at home and sent to the researchers. Cells from participants cheek, nose, mouth, skin, rectum, and/or vagina. The cells may be collected by rubbing the area with a sterile cotton swab. These procedures can also be done at home. Blood. Blood may be drawn using a needle inserted into a vein in the arm. For young children, blood may be collected by a prick on the heel or finger. Intestinal tissue samples. These may be collected from participants who are having an endoscopy or colonoscopy for other reasons. Skin tissue samples. These may be collected from participants who are having biopsies for other reasons.

NCT ID: NCT05647798 Terminated - Pregnancy Clinical Trials

Intrapartum Glycemic Control in GDMA2

Start date: May 22, 2023
Phase: N/A
Study type: Interventional

This is a randomized, parallel, controlled, non-inferiority trial to assess the impact of a tight versus a more liberalized intrapartum glycemic control in gestational diabetic mothers on neonatal glycemia. National guidelines for the management of intrapartum glucose in women with GDM are lacking. This is likely due to the scarcity of high-quality data on the topic.

NCT ID: NCT05642637 Recruiting - Pregnancy Clinical Trials

Biobank Cycle Collection

BCC
Start date: December 6, 2022
Phase:
Study type: Observational

This study will provide daily urine samples from volunteers who are trying to conceive in order to maintain the SPD biobank. Study volunteers, seeking to conceive will be provided with a CE marked Clearblue Ovulation product to help them pinpoint their most fertile time and aid conception. All volunteers will provide daily early morning urine samples throughout the study period and keep a study diary of menses and pregnancy test results for up to 3 menstrual cycles. Urine samples will be received in the clinical laboratory and aliquoted and stored at -80˚C until required.

NCT ID: NCT05634967 Recruiting - Multiple Sclerosis Clinical Trials

Kesimpta (Ofatumumab) Pregnancy Registry

Start date: January 5, 2023
Phase:
Study type: Observational

The Kesimpta Pregnancy Registry is an observational, exposure cohort designed study to examine pregnancy and infant outcomes in women and infants who are exposed to Kesimpta (ofatumumab) during pregnancy to treat MS.

NCT ID: NCT05628675 Completed - Depression Clinical Trials

A Prenatal Bonding Intervention for Pregnant Women With Depression

Start date: November 17, 2022
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to test a group for pregnant women with depression that aims to help them build a stronger relationship with their unborn baby. The main questions it aims to answer are: - Is the group acceptable to pregnant women with depression? - Is it possible to run this group with pregnant women with depression? Participants will be asked to: - attend the group (which lasts 90mins) - complete questionnaires before and after the group, and 1 month later

NCT ID: NCT05621512 Recruiting - Pregnancy Clinical Trials

Workplace Intervention Among Pregnant Hospital Employees

Start date: September 1, 2021
Phase: N/A
Study type: Interventional

The aim of this study is to reduce sick leave and improve wellbeing. This is measured as physical and mental health, general work ability, work-life balance, manager support and completed work adjustments among pregnant health care professionals. It is hypothesised that pregnant employees participating in preventive sessions with their manager and a midwife in addition to the hospital standard pregnancy policy management will have less sick leave and report better wellbeing compared to the reference group.

NCT ID: NCT05620056 Completed - Pregnancy Clinical Trials

A Population-based Study of Drug Exposures and Adverse Pregnancy Outcomes in China (DEEP)

Start date: January 1, 2013
Phase:
Study type: Observational

The DEEP cohort is the first population-based cohort of pregnant population in China that longitudinally documents drug uses throughout the pregnancy life course and adverse pregnancy outcomes.