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Pregnancy clinical trials

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NCT ID: NCT01007110 Completed - Pregnancy Clinical Trials

Effects of Docosahexaenoic Acid (DHA) on Fetal Cardiac Outcomes

Start date: May 2009
Phase: Phase 3
Study type: Interventional

DHA, a type of fatty acid, is important in early development, both in terms of reproductive physiology of gestation and in postnatal behavioral and cognitive function. In adults, DHA has been shown to lower triglycerides and is important to cardiovascular health and autonomic control, lowering heart rate and blood pressure and increasing heart variability. Little is known about how fatty acids impact cardiac control in infants, children or the fetus. Our hypothesis is that maternal DHA supplementation (600 mg/day) will lower fetal HR and increase fetal HRV.

NCT ID: NCT01005667 Withdrawn - Pregnancy Clinical Trials

Study to Determine if Monitoring of Labor Shortens the Time to Delivery

BirthTrack
Start date: n/a
Phase: N/A
Study type: Interventional

The purpose of this study is to test the hypothesis that using the BirthTrack for management of labor shortens the time to delivery and thus improves both maternal and perinatal outcomes.

NCT ID: NCT01005433 Completed - Clinical trials for Pregnant Women Undergoing Cesarean Delivery

Dexmedetomidine for Cesarean Delivery

Start date: December 2009
Phase: Phase 1
Study type: Interventional

Regional anesthesia has become the anesthetic of choice for cesarean section in most countries; however, some women still prefer general anesthesia techniques. There are many trials for the pharmacological modifications of the sympathetic response to surgery, including opioids, tenoxicam, ketorolac, lidocaine and paracetamol. However, opioid administration to the mother before delivery has adverse neonatal effects. This research is a novel trial on the use of dexmedetomidine for suppression of the hemodynamic and hormonal responses of cesarean delivery.

NCT ID: NCT01001689 Completed - Obesity Clinical Trials

Fit For Delivery: A Study of the Effect of Exercise Sessions and Nutritional Counselling on Pregnancy Outcome

FFF
Start date: September 2009
Phase: N/A
Study type: Interventional

"Fit for Delivery" is a randomized, controlled study to examine the effects of an intervention during pregnancy which consists of exercise groups and nutritional counselling. The investigators will assess the outcomes of gestational weight gain, postpartum weight retention, large newborns, glucose regulation, and the incidence of complications of pregnancy and delivery such as gestational diabetes and Cesarean section.

NCT ID: NCT00998712 Recruiting - Pregnancy Clinical Trials

Gestational Diabetes Mellitus and Cardiovascular Disease: The Role of Vascular Dysfunction

Start date: August 2009
Phase: N/A
Study type: Observational

The purpose of this research study is to look at whether there are differences in blood vessel function, risk for developing diabetes (high blood sugar), lipid (blood fat) levels, and levels of other blood markers between black women and white women who have or do not have gestational diabetes mellitus.

NCT ID: NCT00997074 Completed - Pain Clinical Trials

Efficacy Study of Prophylactic Ibuprofen Versus Placebo on Pain Relief and Success Rates of Medical Abortion

Start date: October 2009
Phase: Phase 3
Study type: Interventional

In the current study, we want to evaluate the prophylactic use of ibuprofen versus a placebo for medical abortion by mifepristone and misoprostol, at a gestational age of up to 7 weeks, in regard to the effect on pain relief and the overall procedure success. expected results: The prophylactic use of NSAIDs could offer significant pain relief and thereby a reduction in the need for additional pain relievers compared to the placebo, without interfering with the outcome of medical abortion

NCT ID: NCT00994357 Completed - Diabetes Clinical Trials

The Effect of Real-time Continuous Glucose Monitoring on Severe Complications to Pregnancy in Women With Diabetes

Start date: February 2009
Phase: N/A
Study type: Interventional

The purpose of the study is to investigate the effects of Real-time Continuous Glucose Monitoring on severe complications to pregnancy in women with diabetes.

NCT ID: NCT00991627 Completed - Pregnancy Clinical Trials

Different Approaches to Maternal Hypotension During Cesarean Section

Start date: September 2009
Phase: Phase 4
Study type: Interventional

The aim of this study is to compare two different therapeutic approaches to blood pressure reduction: pharmacological vs. non-pharmacological. The setting is that of patients undergoing scheduled Cesarean section under spinal anesthesia and suffering from aorta-caval compression syndrome, which causes a sudden drop in blood pressure.

NCT ID: NCT00971334 Completed - Pregnancy Clinical Trials

Noninvasive Screening for Fetal Aneuploidy: A New Maternal Plasma Marker

Start date: August 2009
Phase: N/A
Study type: Observational

The purpose of this study is to collect samples for the purpose of developing a prenatal aneuploid test using circulating cell free fetal (ccff) nucleic acid from blood samples from pregnant women who have a high-risk pregnancy undergoing invasive prenatal diagnosis by chorionic villus sampling (CVS) and/or genetic amniocentesis. The results of the ccff aneuploid test will be compared to the chromosomal analysis obtained via CVS or amniocentesis.

NCT ID: NCT00967382 Completed - Pregnancy Clinical Trials

TIPPS: Thrombophilia in Pregnancy Prophylaxis Study

TIPPS
Start date: July 2000
Phase: Phase 3
Study type: Interventional

The TIPPS trial seeks to determine the safety and effectiveness of low-molecular-weight heparin (LMWH), an anticoagulant, in preventing placenta mediated pregnancy complications and venous thromboembolism (VTE) in women with thrombophilia. Thus, the principal research question is: can LMWH prevent thrombosis in the leg veins, pulmonary arteries and placental vessels, thereby reducing the risk of deep vein thrombosis, pulmonary embolism (PE), intrauterine growth restriction (IUGR), preeclampsia, miscarriage and stillbirth?