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Pregnancy clinical trials

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NCT ID: NCT06048276 Active, not recruiting - Pregnancy Clinical Trials

Miscarriage Preventing Herbal Medicines and the Risk of Birth Defects: a Population-based Cohort Study

Start date: January 1, 2023
Phase:
Study type: Observational

Using data from a population-based medicine use cohort in Xiamen, China, this retrospective cohort study will investigate whether herbal medicines used to prevent miscarriage are associated with increased risk of birth defects.

NCT ID: NCT05854992 Active, not recruiting - Clinical trials for Cardiovascular Diseases

Treatments of Migraine With Triptans in Individuals With Elevated Cardiovascular Risk and in Pregnant Women

Start date: July 5, 2022
Phase:
Study type: Observational

Researchers are evaluating the safety of triptan treatment of migraine in individuals with elevated cardiovascular risk and in pregnant women.

NCT ID: NCT05541081 Active, not recruiting - HIV Infections Clinical Trials

Investigating Point-of-care Diagnostics for Sexually Transmitted Infections and Antimicrobial Resistance in Primary Care in Zimbabwe

IPSAZ
Start date: January 12, 2023
Phase: N/A
Study type: Interventional

A prospective interventional study to evaluate a strategy of point-of-care testing for sexually transmitted infections including chlamydia, gonorrhoea, trichomoniasis, syphilis, and Hepatitis B with comprehensive case management including partner notification in antenatal settings in Harare province, Zimbabwe.

NCT ID: NCT05537259 Active, not recruiting - Pregnancy Clinical Trials

BUMPP: A Study to Better Understand Mood During the Perinatal Period

BUMPP
Start date: June 27, 2022
Phase:
Study type: Observational

The overall goal of the BUMPP study is to improve our understanding of a range of moods, feelings, and thoughts that women can experience during pregnancy and soon after they give birth. This study will examine how these moods, feelings, and thoughts are related to changes in hormonal and immune health that women experience during and after pregnancy, and to mother-baby relationships and infant development in the early postpartum months.

NCT ID: NCT05535660 Active, not recruiting - Pregnancy Clinical Trials

Lipid Profile as Predictor of Adverse Maternal and Neonatal Outcomes: A Pilot Study

Start date: July 29, 2022
Phase:
Study type: Observational

The purpose of this study is to ascertain lipid profiles during pregnancy, specifically during the 24-28 week gestation and again near term at 36 weeks gestation. The research team are investigating whether lipid profiles can predict adverse maternal and neonatal outcomes.

NCT ID: NCT05528380 Active, not recruiting - Pregnancy Clinical Trials

Development of a Lifestyle Physical Activity Intervention to Reduce Risk for Perinatal Cannabis Use

Start date: January 30, 2022
Phase: N/A
Study type: Interventional

This study will recruit 20 women who are high risk for prenatal cannabis use for a 12-week program of using the tracker and receiving a Lifestyle Physical Activity program. The primary outcomes will be self reported percent days of cannabis use and physical activity. Secondary outcomes include self -reported measures of depression and anxiety symptoms, adaptive coping, and self-efficacy for cannabis abstinence.

NCT ID: NCT04974892 Active, not recruiting - Pregnancy Clinical Trials

Aspirin and Neutrophils in Preeclampsia

Start date: April 1, 2022
Phase:
Study type: Observational [Patient Registry]

The exact mechanisms by which aspirin prevents the development of preeclampsia in high-risk patients are currently not fully known. Furthermore, a small proportion of high-risk patients who are on low-dose aspirin (LDA) still go on to develop preeclampsia (PE). This longitudinal observational study will assess the immune profile in participants who are taking low dose aspirin (LDA) in pregnancy. As part of routine care, patients at high risk of developing preeclampsia are treated with LDA from 16 weeks gestation. The study will be conducted at Barts Health National Health Service (NHS) Trust. The study population will comprise of 2 groups of participants: 1. Those who respond to LDA and do not develop preeclampsia (responders) 2. Participants who do not respond to LDA and develop preeclampsia (non responders) Participants will be consented at their booking appointment. Participants will be eligible if they have a singleton pregnancy and are aged over 18 years. They will have an additional blood sample taken at 12, 20, 28 and 36 weeks gestation. The blood samples will be tested to assess immune cell function, metabolism and genetics. This will identify cumulative changes in immunobiology at key time points in pregnancy.

NCT ID: NCT04961840 Active, not recruiting - Pregnancy Clinical Trials

A Study to Assess Maternal and Fetal Outcomes After Taking Prucalopride During Pregnancy

Start date: January 1, 2022
Phase:
Study type: Observational

This study will collect information on pregnant women diagnosed with constipation from their health care insurance claims records. It will include the following groups: - Those who took prucalopride. - Those who took other medicines for constipation. - Those who did not take any prescription medicines for constipation. The main aim of the study is to assess the risk of major birth defects with the mother's use of prucalopride during the first 3 months of pregnancy. The study uses existing health care insurance information; participants are not enrolled, treated, or required to visit the doctor during this study.

NCT ID: NCT04571684 Active, not recruiting - HIV Clinical Trials

Evaluating HITSystem 2.1 to Improve Viral Suppression in Kenya

Start date: October 5, 2020
Phase: N/A
Study type: Interventional

The goal of this project is to rigorously evaluate the efficacy of HIV Infant Tracking System 2.1 (HITSystem, an eHealth intervention that uses short message service (SMS) texts to patients and algorithm-driven electronic alerts for providers) to increase retention in guideline-adherent prevention of mother-to-child transmission of HIV services (PMTCT) and to increase viral suppression and appropriate clinical action through the extended period of 6 months postpartum, compared to standard of care PMTCT services in a matched, cluster randomized controlled trial.

NCT ID: NCT04432779 Active, not recruiting - Covid-19 Clinical Trials

Impact of COVID-19 Infection During Pregnancy on Newborns and Young Children

ELIKYA COVID
Start date: May 25, 2020
Phase:
Study type: Observational

This study aim is to assess impact of COVID-19 infection during pregnancy on outcome of pregnancy, and on developement of the child in early life.