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Pregnancy Related clinical trials

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NCT ID: NCT04714905 Completed - Pregnancy Related Clinical Trials

Better Understanding the Metamorphosis of Pregnancy (BUMP)

BUMP
Start date: February 23, 2021
Phase:
Study type: Observational [Patient Registry]

Pregnancy is a commonly occurring medical event. Women who are pregnant may experience pregnancy-related symptoms and complications. However, there is a relative lack of multi-dimensional data on large populations of pregnant patients. The Study Investigators aim to derive novel insights and deeper understanding of maternal physiology and pathology through the analysis of an unprecedented breadth and depth of data collected from connected devices (i.e., wearables, smart home scale, mobile apps, etc.), additional virtual study assessments and support calls, and information derived from standard of care clinical visits. They will share these insights to empower patients to better care for themselves. The Investigators hope to know how leveraging the data collected from connected devices in addition to information obtained from routine clinical care helps researchers and clinicians better understand pregnancy related symptoms, conditions, and complications.

NCT ID: NCT04712994 Completed - HIV Infections Clinical Trials

PrEPARE: PrEP in Pregnancy, Accelerating Reach and Efficiency

Start date: May 1, 2021
Phase: N/A
Study type: Interventional

This study tests strategies for improving PrEP implementation in maternal and child health clinics using a difference-in-difference approach.

NCT ID: NCT04711317 Completed - Anesthesia Clinical Trials

Pre-oxygenation With High-flow Nasal Cannula in Caesarian Section Under General Anesthesia

PRIOROB
Start date: March 3, 2021
Phase: N/A
Study type: Interventional

The investigators and other groups have demonstrated that high-flow nasal oxygen used during preoxygenation for emergency surgery is at least equally effective as preoxygenation compared to standard tight fitting mask. The investigators also have data from a recent study that indicates that high-flow nasal oxygen might decrease the risk of clinically relevant desaturation below 93% of arterial oxygen saturation. The studies investigating the concept of high-flow nasal oxygen has up to this date excluded pregnant women. Pregnant woman is a patient group with known difficulties to maintain adequate saturation levels during apnoea. Due to smaller functional residual capacity their oxygen stores after preoxygenation are smaller compared to patients with a normal body mass index. The pregnant woman also have a higher oxygen demand and metabolism due to the growing placenta and the fetus. Pregnant women are therefore a patient group where a method that could prolong time until desaturation would be even more valuable and potentially could save lives. Based on the above, the investigators now aim to conduct a clinical pilot study, where pregnant women undergoing caesarian section under general anesthesia are pre and perioxygenated with high-flow nasal oxygen. Data from that group will be compared with patients preoxygenated in a traditional manner with tight facemask. This study is done to evaluate an established technique on a patient category that in theory could gain a lot from it.

NCT ID: NCT04703270 Completed - Pregnancy Related Clinical Trials

Understanding COVID-19 Infection in Pregnant Women and Their Babies

periCOVID
Start date: January 4, 2021
Phase:
Study type: Observational

This national study will recruit expectant mothers with and without positive nasopharyngeal swabs for SARS-CoV-2, and aims to determine the seroepidemiology of SARS-CoV-2 amongst expectant mothers and their infants in the U.K.

NCT ID: NCT04694664 Completed - Pregnancy Related Clinical Trials

COVID-19 Vaccine Confidence Among Pregnant Women and Mothers

VCCOVID
Start date: October 1, 2020
Phase:
Study type: Observational

The purpose of this study is to assess the level of vaccine confidence and influencers among pregnant women and mothers of school-aged children during the COVID-19 pandemic.

NCT ID: NCT04658810 Completed - Pregnancy Related Clinical Trials

Assessment of Post-traumatic Stress Disorder (PTSD) in Patients Monitored for Cytomegalovirus (CMV) Seroconversion During Pregnancy,

PTSD CMV
Start date: May 2, 2021
Phase:
Study type: Observational

Reports of maternal seroconversion to CMV during pregnancy can be extremely stressful. This virus is little known to the general public and searching for information on the Internet quickly leads to a consultation of a site mentioning the risk of severe psychomotor retardation in the event of prenatal cytomegalovirus infection. The psychological repercussions in the event of prenatal CMV infection with criteria of severity, leading or not to a request for IMG, is undeniable, but no study has investigated the consequences of seroconversion to CMV without transmission of the virus to the patient fetus, or in the case of transmission without criteria of seriousness, on the patient's experience during and after her pregnancy. Such a study would, if necessary, improve the care and support of these future mothers

NCT ID: NCT04651309 Completed - Pregnancy Related Clinical Trials

Assessment of Labour Progress by Intrapartum Ultrasound

Start date: August 27, 2019
Phase: N/A
Study type: Interventional

Assessment of labor progress via digital exams is considered the standard of care in most delivery rooms. However, this method can be stressful, painful and imprecise and multiple exams increase the risk for chorioamnionitis. Trans-perineal ultrasound (TPUS) was found to be an objective noninvasive way to monitor labor progress. The study aim is to investigate whether, in nulliparous women, the use of TPUS during labor can reduce the number of vaginal exams and the incidence of chorioamnionitis.

NCT ID: NCT04638504 Completed - Pregnancy Related Clinical Trials

Comparison of Brachial Artery Dilatation, Uterine Artery Doppler, Umbilical Artery Doppler and 1st-trimester Visceral Adipose Tissue Measurement in Obese and Normal Pregnant Women

Start date: November 19, 2020
Phase:
Study type: Observational

Brachial artery flow-mediated in obese and normal-weight pregnant women dilation of uterine artery doppler and umbilical artery doppler results comparison of

NCT ID: NCT04635839 Completed - Pregnancy Related Clinical Trials

Heparin Prophylaxis Dosing for Antepartum Hospitalizations (HEPDOSE)

Start date: December 15, 2020
Phase: Phase 4
Study type: Interventional

This study is a randomized control trial to compare gestational age-based dosing with standard dosing of unfractionated heparin for thromboprophylaxis of hospitalized antepartum patients. The investigators aim to determine the effect of dosing on receipt of neuraxial anesthesia and pregnancy outcomes and evaluate the pharmacokinetics and pharmacodynamics of unfractionated heparin in pregnancy.

NCT ID: NCT04633395 Completed - Insomnia Clinical Trials

Treating Pregnancy Related Insomnia With Music

Start date: December 1, 2020
Phase: N/A
Study type: Interventional

This study aims to examine the effects of 4 weeks music listening at bedtime on sleep quality during the third trimester of pregnancy.