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Prediabetic State clinical trials

View clinical trials related to Prediabetic State.

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NCT ID: NCT04734132 Completed - PreDiabetes Clinical Trials

Effects of Moringa Oleifera Leaves on Glycemia, Lipemia and Inflammatory Profile in Prediabetic Patients

NUTRIMOL-DB
Start date: January 22, 2019
Phase: N/A
Study type: Interventional

Moringa oleifera (MO) is a traditional food in tropical and subtropical areas and has attained a growing interest for its medicinal properties. It's a nutrient-rich vegetable, high in protein and polyphenol content. The MO dry leaves and leaf extracts have been shown to exert numerous in vitro activities and in vivo effects, including the hypoglycemic effect. Thus, MO could be an alternative to prevent or treat diabetes. Studies in humans, however, are still limited. This proposal aims to study the efficacy of Moringa oleifera to improve the control of glycaemia in subjects with prediabetes. A 3-month dietary intervention with MO dry leave capsules will be performed and compared to placebo.

NCT ID: NCT04722354 Active, not recruiting - Pre Diabetes Clinical Trials

Abscisic Acid Effects on Glucose Homeostasis and Insulin Sensitivity

ABA
Start date: March 8, 2021
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine the effects of oral abscisic acid (ABA) on glucose metabolism in subjects with defined prediabetes.

NCT ID: NCT04705779 Active, not recruiting - Obesity Clinical Trials

The HARMONY Study: A Intervention to Reduce Cardiometabolic Risk in African American Women

Start date: May 20, 2021
Phase: N/A
Study type: Interventional

This study will test whether a culturally-tailored nutrition and exercise intervention designed for African-American women will lead to sustained improvements in exercise and healthy eating through improvements in self-management mediators: mindfulness, stress management, positive reappraisal, self-regulation, and self-efficacy.

NCT ID: NCT04705558 Recruiting - PreDiabetes Clinical Trials

Combination of Ketogenic Diet and Exercise on Prediabetes in Female With Normal Weight

Start date: July 20, 2020
Phase: N/A
Study type: Interventional

Individuals with prediabetes have a high risk of developing type 2 diabetes. The purpose of this study was to compare the effect of combination of ketogenic diet and aerobic exercise interventions versus ketogenic diet alone on the glucose level in prediabetes female with normal weight.

NCT ID: NCT04702477 Completed - Diabetes Clinical Trials

Mindfulness Training and Group Counseling Among Prediabetes and Diabetes Patients

Start date: August 1, 2018
Phase: N/A
Study type: Interventional

Examining a number of health outcomes in those with diabetes and prediabetes before and after a group-based mindfulness intervention.

NCT ID: NCT04688359 Completed - Clinical trials for Cardiovascular Risk Factor

Effectiveness of Nurse-coordinated Follow-up Program in Primary Care for People at Risk for T2DM

Start date: November 1, 2021
Phase: N/A
Study type: Interventional

Previous Icelandic studies regarding prevalence of diabetes have mostly used data from the capital area. Information on the proportion of people at risk at developing T2DM or having undiagnosed T2DM among people living in rural Northern Iceland is unknown. Clinical guidelines recommend that patients with prediabetes (diabetes warning signs) should be referred to a counselling program. The study will evaluate effectiveness of nurse-coordinated Guided Self-Determination (GSD) follow up program toward health promotion, for people at risk of T2DM.

NCT ID: NCT04666636 Recruiting - PreDiabetes Clinical Trials

Mechanisms for Activation of Beige Adipose Tissue in Humans

Start date: December 7, 2020
Phase: Phase 2
Study type: Interventional

Mirabegron (Myrbetriq®, Astellas) is a highly specific and well-tolerated ß3 agonist marketed for overactive bladder. This trial will assess the effects of mirabegron on glucose tolerance and adipose tissue in prediabetic patients

NCT ID: NCT04657367 Recruiting - Obesity Clinical Trials

Polish Registry of Diabetes (PolReD)

PolReD
Start date: February 3, 2020
Phase:
Study type: Observational [Patient Registry]

The aim of this project is to create a registry of diabetic patients, containing a detailed clinical profile of each patient, along with omics data, which will be analyzed using artificial intelligence algorithms, and their results will be implemented in the form of new recommendations of care for high-risk patients and those already suffering from diabetes. The study will be conducted prospectively. The project participants will be patients with diabetes, patients at high risk of developing diabetes and a control group of normoglycemic patients who will participate in study visits at the Clinical Research Center of the Medical University of Bialystok.

NCT ID: NCT04653220 Completed - Obesity Clinical Trials

Metabolic Response Evaluation of Low-sugar Snack Bars

Start date: November 13, 2019
Phase: N/A
Study type: Interventional

To determine the post-prandial metabolic response and biomarker response, following the consumption of newly developed low glycaemic index (GI) snack bars. The snack bars are formulated with different combinations and ratios of ingredients and food structures. The low sugar products maintaining glucose homeostasis and preventing metabolic problems may have commercial potential as a novel functional ingredient in a variety of fields, including nutrition, medicine, and agriculture.

NCT ID: NCT04653207 Completed - Obesity Clinical Trials

The Dose Effects of Isomaltulose and Sucrose on Glycaemic and Insulinemic Response

Start date: March 1, 2018
Phase: N/A
Study type: Interventional

This study will determine the glycaemic and insulinaemic response and sensory profile of the drinks with various ratios sucrose:isomaltulose. The information will be useful for manufacturers of beverages to produce blood glucose friendlier drinks. The information will also be useful for dieticians and clinicians in recommending foods and drinks for people with diabetes. The information will also be useful to the public for making better food choices. The data will also provide insights on how the different ratios of sweeteners may affect glycaemic and insulinaemic indices (GI and II).