The Effect of Peripartum Magnesium Sulfate Use on the Occurrence of Postpartum Depression

Postpartum Depression Clinical Trial

Official title:

The Effect of Peripartum Magnesium Sulfate Use on the Occurrence of Postpartum Depression

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05751746
• Other study ID #: B-2209-780-302
• Status: Recruiting
• Start date: January 30, 2023
• Est. completion date: February 28, 2024

Study information

• Verified date: February 2023
• Source: Seoul National University Bundang Hospital
• Contact: Su Yeon Kim, Dr.
• Phone: +82-10-3325-2690
• Email: kittyrockz[@]nate.com
• Is FDA regulated: No
• Study type: Observational [Patient Registry]

Clinical Trial Summary

This is an observational study that will be conducted on pregnant women under vaginal delivery or cesarean section. The magnesium sulfate will be given to appropriate participants with a protocol that obstetrician are already using in our hospital. After delivery, participants are asked to answer sequential questionnaires to assess postpartum depression.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 108
• Est. completion date: February 28, 2024
• Est. primary completion date: December 31, 2023
• Accepts healthy volunteers: No
• Gender: Female
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Pregnant women who will do delivery.

• Gestational week >= 30 week

• Singleton

Exclusion Criteria:

• History of depression

Related Conditions & MeSH terms

• Depression
• Depression, Postpartum
• Depressive Disorder
• Postpartum Depression

Intervention

Drug:
• Magnesium sulfate
Magnesium sulfate will be administered following a protocol that obstetricians already use in our hospital.

Locations

Country	Name	City	State
Korea, Republic of	Seoul National University Bundang Hospital	Seongnam-si	Gyeonguido

Sponsors (1)

Lead Sponsor	Collaborator
Seoul National University Bundang Hospital

Country where clinical trial is conducted

Korea, Republic of, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	postpartum depression	depression diagnosis using K-EPDS(Korean version of Edinburgh Postnatal Depression Scale) on a scale of 7 to 30 points.	6 week after discharge
Primary	postpartum depression severity	depression severity using K-EPDS; mild (7~13 points), moderate (14~19 points), severe (20~30 points)	6 week after discharge
Secondary	postpartum depression	depression diagnosis using K-EPDS(Korean version of Edinburgh Postnatal Depression Scale) on a scale of 7 to 30 points.	2week after discharge
Secondary	postpartum depression severity	depression severity using K-EPDS; mild (7~13 points), moderate (14~19 points), severe (20~30 points)	2 week after discharge