The Relationship Between Oxytocin Level and Postpartum Depression

Postpartum Depression Clinical Trial

Official title:

The Relationship Between Oxytocin Level Measured During Pregnancy and Postpartum Depression Symptoms

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04427410
• Other study ID #: TYL-2019-12476
• Status: Completed
• Start date: July 20, 2019
• Est. completion date: February 20, 2020

Study information

• Verified date: June 2020
• Source: Cukurova University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

There are studies in the literature that associate oxytocin level with postpartum depression. This study was carried out to investigate the relationship between oxytocin levels measured during pregnancy and postpartum depression symptoms.

Description:

Introduction and purpose: There are studies in the literature that associate oxytocin level with postpartum depression. This study was carried out to investigate the relationship between oxytocin levels measured during pregnancy and postpartum depression symptoms.

Method: The study was conducted with 70 women who met the research criteria. Data collection was done in two interviews. The first meeting is 30-38 at the week of gestation, the second interview is 4-12 at the week of postpartum. It was done between weeks. In each interview, a data collection form was applied first and then a saliva sample was taken. Data collection form; The questions prepared by the researchers consisted of the Edinburgh Postnatal Depression Scale (EPDS) and Beck Depression Inventory (BDI). The data were analyzed using SPSS 22.0 program and the significance value was taken as p <0.05.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 70
• Est. completion date: February 20, 2020
• Est. primary completion date: October 20, 2019
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• 18 years of age or older, and having a pregnancy of 30 weeks or more

Exclusion Criteria:

• previous mental illness history, miscarriage or stillbirth history, multiple pregnancy, fetal malformation, antidepressant or anxiolytic drug use, existing chronic disease,preterm labor is the development of maternal or neonatal complications at birth, hospitalization in the neonatal intensive care unit or congenital disease.

Related Conditions & MeSH terms

• Depression
• Depression, Postpartum
• Depressive Disorder
• Oxytocin Deficiency
• Postpartum Depression
• Prenatal Stress

Intervention

Diagnostic Test:
• Salivary test
Salivary test for measured of oxytocin levels

Locations

Country	Name	City	State
Turkey	Cukurova University	Adana	Saricam

Sponsors (2)

Lead Sponsor	Collaborator
Cukurova University	Ayseren Cevik

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Oxytocin levels	Oxytocin levels in pregnancy and postpartum period	3-6 month