Can Oxytocin Level Predict Postpartum Depression?

Status Completed

Clinical Trial Summary

The goal of this research study is to understand the relationship between the hormone oxytocin and postpartum mood.

Clinical Trial Description

Postpartum depression (PPD) affects some one in five new mothers, and adversely influences maternal adaptation to motherhood. While it is known that women with a prior history of depression, or depression during pregnancy, are at elevated risk for postpartum depression, many women with no prior history of depression or other risk factors go on to develop depression in the postpartum period. Considering the grave consequences of postpartum depression on maternal infant bonding and childhood psychological development, it is critical to develop reliable methods to identify which women, who are not depressed during pregnancy, will become depressed after delivery. The biological pathways leading to depression at any time in life, including around pregnancy, are still poorly characterized. Oxytocin (OT), a hormone involved in delivery and lactation, has received recent attention regarding its additional role in maternal emotions and care taking behaviors after birth. The primary goal is explore the relationship between plasma oxytocin and postpartum mood. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02020148
Study type	Observational
Source	Northwestern University
Contact
Status	Completed
Phase
Start date	December 2013
Completion date	August 2015

View Details

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