Postpartum Anemia and Postpartum Depression

Postpartum Depression Clinical Trial

— PPADS  

Official title:

Is Postpartum Anemia an Independent Risk Factor for Development of Postpartum Depression?

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00782912
• Other study ID #: 08-155
• Status: Completed
• Start date: November 2008
• Est. completion date: October 2014

Study information

• Verified date: February 2019
• Source: St. Michael's Hospital, Toronto
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Postpartum anemia (PPA) and Postpartum depression (PPD) are common afflictions affecting women after childbirth. Both disorders have a significant impact on women's health and functional status. Despite common symptoms and characteristics, a link between these entities has not been adequately studied. The objective of this study is to determine whether postpartum anemia is an independent risk factor for the development of postpartum depression. This prospective cohort study will include all women delivered by elective term cesarean delivery. Hemoglobin and iron levels will be measured, standardized questionnaires for assessment of PPD, functional status and lactation will be administered before discharge and at 3 & 6 weeks post partum. Hemoglobin levels at each time point will be analyzed for correlation with depressive symptoms, functional status and lactation success.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 103
• Est. completion date: October 2014
• Est. primary completion date: October 2014
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• Women after term elective cesarean section

Exclusion Criteria:

• age < 16 years, preterm (< 37 weeks) delivery, multiple gestation, symptomatic anemia necessitating blood transfusion, significant fetal anomalies or infant not discharged with mother for other reason, preexisting severe chronic maternal illness, preexisting maternal depression and/or current use of antidepressants, other psychiatric illness (e.g. bipolar disease, schizophrenia) or preexisting hemoglobinopathy

Related Conditions & MeSH terms

• Anemia
• Depression
• Depression, Postpartum
• Depressive Disorder
• Postpartum Depression

Locations

Country	Name	City	State
Canada	St. Michael's Hospital	Toronto	Ontario

Sponsors (1)

Lead Sponsor	Collaborator
St. Michael's Hospital, Toronto

Country where clinical trial is conducted

Canada, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Incidence of postpartum depression		0-6 weeks postpartum
Secondary	Mean Edinburgh Postnatal Depression Scale results		0-6 weeks postpartum
Secondary	Functional status		0-6 weeks postpartum
Secondary	Lactation success		0-6 weeks postpartum