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Post-operative Pain clinical trials

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NCT ID: NCT06104254 Recruiting - Post Operative Pain Clinical Trials

Education Importance and Pain Belief Differences Among Patients Who Underwent Orthopedic Surgery

Start date: November 1, 2023
Phase: N/A
Study type: Interventional

The assessment of pain plays a crucial role in pain management. Nurses are instrumental in the identification, evaluation, and initiation of pain management strategies. In the literature, it is strongly recommended to provide education about postoperative pain management to patients, their families, and those responsible for patient care. Additionally, the development of a pain management plan and goals is advocated. The optimal timing, content, and objectives of patient education depend on the type of pain (acute or chronic), the availability and effectiveness of treatment, and the patient's level of education and literacy. Educating individuals undergoing elective surgery or outpatient treatment about the likelihood and magnitude of acute pain they may experience, as well as informing them about available methods to prevent or alleviate this pain, is critical for pain management. Shindo et al. conducted a study suggesting that perioperative pain education significantly reduces postoperative opioid use. According to the Health Belief Model, an individual's perception of health is influenced by their perception of the value of health, beliefs about illness, and beliefs about the consequences of illness. Therefore, when a patient's health beliefs and attitudes are determined, health education and treatment planning can be tailored more appropriately.

NCT ID: NCT06089512 Completed - Analgesia Clinical Trials

Comparison of Midpoint Transverse Process to Pleura Block and Thoracic Paravertebral Block

Start date: November 1, 2022
Phase: N/A
Study type: Interventional

In this study, hypothesis is that the MTPB (mid point transverse process block), which is easier and has fewer complications in patients aged 18-80 undergoing video-assisted thoracic surgery (VATS), provides analgesia as effective as PVB.

NCT ID: NCT06089200 Completed - Post Operative Pain Clinical Trials

TAP Block vs Spinal Orphine for Postoperative Caesarean Section Analgetics

Start date: February 23, 2023
Phase: Phase 2
Study type: Interventional

The goal of this randomized controlled trial is to compare the effect of TAP block vs spinal morphine for post caesarean section analgesics. The main questions it aims to answer are: - Which post op analgesic method works better for patients who underwent caesarean section - The number of additional opioid needed

NCT ID: NCT06088420 Recruiting - Post Operative Pain Clinical Trials

Analgesic Efficacy of Different Nerve Blocks in Postoperative Cesarean Section

Start date: October 2023
Phase: N/A
Study type: Interventional

comparing analgesic efficacy of different nerve blocks on post operative cesarean sections.

NCT ID: NCT06086535 Recruiting - Post Operative Pain Clinical Trials

Intercostal Nerve Cryoanalgesia vs BRILMA Block for Minithoracotomy on Cardiac Surgery

Start date: February 18, 2023
Phase:
Study type: Observational

Patients undergoing cardiac surgery by minithoracomy present severe acute postoperative pain. Cryoanalgesia of the intercostal nerves and BRILMA block can provide a solution for this postoperative pain. The main aim of this study is to compare the postoperative analgesia provided by BRILMA block and intercostal nerve cryoanalgesia in patients undergoing cardiac surgery by minitoractomia.

NCT ID: NCT06082479 Completed - Inflammation Clinical Trials

The Effect of Intra Oral Cryotherapy in Patients With Symptomatic Apical Periodontitis

Start date: September 1, 2022
Phase: N/A
Study type: Interventional

The participants were divided into two groups: Group I (cryotherapy) (n =10) after the completion of the mechanical preparation intra oral cryotherapy was applied. Group II (control) (n =10) received standard root canal treatment without the application of any type of cryotherapy.

NCT ID: NCT06079047 Recruiting - Post Operative Pain Clinical Trials

Perineural Dexamethasone in the Adductor Canal Block

Start date: December 15, 2023
Phase: N/A
Study type: Interventional

Postoperative pain management in total knee arthroplasty (TKA) surgery is a real challenge for the anesthesiologist. Effective pain control must be provided while preserving the mobility to ensure early rehabilitation. The adductor canal block is an effective way to induce sensory block without motor block. However, the major disadvantage of this block is the duration of sensory block which may be insufficient for postoperative pain management in TKA surgery. Many studies have focused on finding molecules that can prolong sensory block without the need for a perineural catheter and dexamethasone is among the most studied molecules(1, 2). Hence, our study aims to evaluate the added value of perineural dexamethasone in the adductor canal block in TKA surgery. [

NCT ID: NCT06077214 Recruiting - Clinical trials for Bariatric Surgery Candidate

Liposomal Bupivacaine for Post-operative Pain Control in Adolescent Bariatric Patients

Start date: January 31, 2023
Phase: Phase 1
Study type: Interventional

Liposomal bupivacaine (trade name Exparel) is a local analgesic that is designed to produce more long-term pain control. Bupivacaine, a widely used local analgesic, is stored within liposomes, which break down in soft tissue over time. Typical length of therapeutic effect for standard bupivacaine is up to 6 hours. The liposomal formulation of bupivacaine, however, has a length of therapeutic effect of up to 72 hours. Typical post-operative incisional pain is known to last for several days in most cases and is thought to peak between 1-2 days after surgery. Therefore, the benefit of most short-acting local analgesics does not overlap with the period of most need.

NCT ID: NCT06071988 Recruiting - Pain Clinical Trials

Long Term Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Traumatic or Post-operative Peripheral Neuropathy

Start date: November 2, 2023
Phase: Phase 3
Study type: Interventional

Over the last years a rising medical need for treatment of chronic pain was identified. Based on previous findings indicating the pain modulating effects of cannabinoids in chronic pain disorders, this clinical trial investigates the long term efficacy and tolerability of the THC-focused nano endocannabinoid system modulator AP707 in patients with chronic pain disorders due to traumatic or post-operative peripheral neuropathy. Patients receive AP707 or placebo over the course of 14 weeks as an add-on to the standard of care. Changes in pain intensity, quality of life and sleep and others measures are monitored through different scales to assess the efficacy of AP707 in patients with chronic pain due to traumatic or post-operative peripheral neuropathy.

NCT ID: NCT06071936 Recruiting - Pain Clinical Trials

Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Traumatic or Post-operative Peripheral Neuropathy

Start date: November 2, 2023
Phase: Phase 3
Study type: Interventional

Over the last years a rising medical need for treatment of chronic pain was identified. Based on previous findings indicating the pain modulating effects of cannabinoids in chronic pain disorders, this clinical trial investigates the efficacy and tolerability of the THC-focused nano endocannabinoid system modulator AP707 in patients with chronic pain disorders due to traumatic or post-operative peripheral neuropathy. Patients receive AP707 or placebo over the course of 14 weeks as an add-on to the standard of care. Changes in pain intensity, quality of life and sleep and others measures are monitored through different scales to assess the efficacy of AP707 in patients with chronic pain due to traumatic or post-operative peripheral neuropathy.